Soothing Cream Moisturizer
Ingredients overview
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Biopelle Soothing Cream MoisturizerIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
We don't have description for this ingredient yet.
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>
If you are into the K-Beauty trend, you must have bumped into snail slime like a thousand times. Korean brands love the ingredient and tout it for its miraculous repair and hydration properties. It's claimed to be able to repair everything from dry patches, acne breakouts to signs of aging and we are happy to say that it might be just true.
So snail slime is the yucky stuff that snails (in cosmetics the secretion of Cornu Aspersum, the garden snail is used) produce when they are in stress (it's not the same as the one they secret to be able to move nicely and smoothly). As the cosmetic chemists at the Beauty Brains blog write, "chemically speaking, snail slime is a complex mixture of proteoglycans, glycosaminoglycans, glycoprotein enzymes, hyaluronic acid, copper peptides, antimicrobial peptides and trace elements including copper, zinc, and iron." English translation equals it's loaded with a bunch of good-for-the-skin stuff.
As for scientific proof that snail slime does something for the skin, we did find a couple of studies to go by. A Spanish radiation oncologist, Rafael Abad Iglesias MD discovered for the first time that snail mucin can be used to treat radiation dermatitis (skin irritation caused by radiotherapy, a form of cancer treatment). He did a clinical study with 100 patients and reported a "statistically significant clinical improvement in erythema, itching and burning pain" in the group treated with snail slime.
A 2007 study examined the molecular basis for the great regeneration properties of the ingredient. It found that snail slime (SS) indeed does a bunch of positive things that could be the reason for its great repair abilities. First, it has serious antioxidant properties thanks to two great antioxidant enzymes, superoxide dismutase and glutathione s-transferase. Second, SS induces fibroblast proliferation, that's particularly important during wound healing. Third SS was also found to downregulate MMP, an evil enzyme that's out there to destroy skin-firming collagen. These properties add up to give SS not only wound healing and regenerative properties but also serious anti-aging potential.
Regarding anti-aging, a 2013 study in the Journal of Drugs in Dermatology examined the effect of SS on photoaged skin. The 14-week, double-blind, 25 participant study found that "there was a significant degree of improvement in fines lines", though the participants did not report a significant difference in the quality of their skin.
All in all, we think that snail slime definitely deserves the skin goodie status it already enjoys in the K-beauty space. If you have no problem with somewhat strange, yucky things or animal derived ingredients in your products, it's worth a try.
An often used emollient with a light and silky feel. It's very mild to both skin and eyes and spreads nicely and easily. It's often used in sunscreens as it's also an excellent solvent for sunscreen agents.
A 100% natural and plant-derived moisturizer that mimics the natural carbohydrate fraction found in the upper layer of the skin. Its special magic power is to bind to the skin stronger and longer than other moisturizer ingredients do so it can keep the skin hydrated longer than usual.
Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.
Hexylene Glycol is also part a preservative blend named Lexgard® HPO, where it helps the effectiveness of current IT-preservative, phenoxyethanol.
We don't have description for this ingredient yet.
A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities.
A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky.
It works over a wide pH range and is used between 0.5-1.2%.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
Fancy name for fruit sugar. It has nice water-binding properties and helps to keep skin hydrated.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
A fancy name for sugar. Luckily when you put it on your skin it's good for you not like when you eat it. :) It has water-binding properties, which means that it helps to keep your skin nice and hydrated.
The extract coming from the Indian Frankincense, a medium-sized tree native to India. Mostly the gum-resin is used that is obtained from an incision made on the trunk of the tree. It contains about 30-60% resin, 5-10% fragrant essential oil, and the rest is made up of polysaccharides (mostly arabinose, galactose, xylose).
The biologically most active components of the resin are boswellic acids that have anti-inflammatory properties. According to manufacturer info, the boswellic acids rich resin extract is also a potent inhibitor of elastase (an enzyme that breaks down proteins, including collagen) and has antiGAGase activity (protecting the important natural moisturizing factors, glycosaminoglycans in the skin) meaning that it can help the skin to stay firm for a longer time.
The reason why we did not award Boswellia Serrata Extract a goodie status is that this INCI name is not clear enough on the type of the extract. It might be a boswellic acids rich, anti-inflammatory extract (that is a goodie) or it might be a fragrant essential oil rich extract used in perfumery or aromatherapy that can be a problem for sensitive skin types.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
A type of lipid that's the major (about 75%) component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient.
It has a water-loving head with two water-hating tails and this structure gives the molecule emulsifying properties. It is also often used to create liposomes, small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and help its absorption.
A little helper ingredient that can be a thickener, a humectant, a foam booster, an adhesion promoter and a filler. It's a blend of polysaccharides that helps to moisturize and soften the skin.
A type fo sugar, usually refined from cane or beet sugar. On the skin, it has water-binding properties and helps to keep your skin hydrated.
Yes, it's the thing that can be found naturally in pee. And in the skin. It is an awesome natural moisturizing factor, aka NMF. NMFs are important components that help the skin to hold onto water and keep it plump, elastic and hydrated. Urea makes up about 7% of NMFs next to other things such as amino acids (40%), PCA (12%) or Lactate (12%).
What makes urea special, is that it is not only a simple moisturizer, but it is thought to be a "small-molecule regulator of epidermal structure and function" meaning that it has a bunch of extra biological activities. It acts as a mild keratolytic agent (some of its moisturizing action is thought to come from urea's ability to break down bonds in the protein called filaggrin and thus freeing up amino acids in the skin), enhances antimicrobial peptide expression and improves skin barrier function.
Being a mild keratolytic agent and strong moisturizer means that high-percentage (10-40%) urea treatments are found effective in a bunch of skin disorders connected to excessive dryness and malfunctioning skin barrier such as ichthyosis, xerosis, psoriasis, eczema and seborrheic dermatitis.
Overall, just like glycerin, urea is a real oldie but a goodie, a nice ingredient in any moisturizer.
It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. Together with ceramides and fatty acids, they play a vital role in having a healthy skin barrier and keeping the skin hydrated.
Apart from being an important skin-identical ingredient, it's also an emollient and stabilizer.
A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). Can be derived from coconut or palm kernel oil.
A non-essential amino acid (a building block of skin proteins like collagen or elastin) that hydrates the skin.
A non-essential amino acid (important building block of collagen and elastin) that hydrates the skin. It is also used to set the pH of the cosmetic product (buffering).
Glutamic acid is a little molecule and non-essential (our body can synthesize it) amino acid with the important job of being a neurotransmitter in the human body meaning that it helps your nervous system work correctly.
As for what it's doing in cosmetics, Glutamic acids' main thing (similar to other amino acids) is being a humectant moisturizer and skin-conditioning agent (sidenote: if you attach lots of glutamic acid molecules, you get polyglutamic acid that is claimed to be a better than hyaluronic acid humectant). It also seems to affect skin barrier repair, however, it is not clear-cut in which direction.
The complication is that glutamic acid has two distinct forms, L-glutamic acid and D-glutamic acid, that are the mirror images of each other (think of it like your left and right hand). Studies show that a topical application of L-glutamic acid on damaged skin delayed skin repair, while D-glutamic acid application sped up skin repair. As both forms are used by the industry, it is a bit uncertain what you are getting with just glutamic acid on the ingredient list (but if it is a Shiseido group product, it is probably the goodie D-form :)).
Other than that, Glutamic acid can also be used as a pH adjuster and can be processed via biological pathways into pyrrolidone carboxylic acid, the sodium salt of which is a goodie and one of your skin’s natural moisturizing factors.
There is not too much info out there about Hexyl Nicotinate. It's an emollient, moisturizer ingredient. Also according to this study it increases blood flow.
The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon.
Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing that when exposed to sunlight, MP treated skin cells suffered more harm than non-MP treated skin cells. The study was not done with real people on real skin but still - using a good sunscreen next to MP containing products is a good idea. (Well, in fact using a sunscreen is always a good idea. :))
A very common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon.
A little helper ingredient that is used to adjust the pH of the product. It also helps to keep products stay nice longer by neutralizing the metal ions in the formula (they usually come from water).
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
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| what‑it‑does | solvent |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | antioxidant | moisturizer/humectant |
| what‑it‑does | emollient | antimicrobial/antibacterial |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | solvent | emulsifying | perfuming | surfactant/cleansing |
| irritancy, com. | 0-1, 0-2 |
| what‑it‑does | solvent |
| what‑it‑does | viscosity controlling |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | soothing |
| what‑it‑does | emollient |
| what‑it‑does | preservative |
| what‑it‑does | skin-identical ingredient | emollient |
| what‑it‑does | viscosity controlling | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant | soothing |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 2, 2 |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | emollient |
| what‑it‑does | preservative |
| irritancy, com. | 0, 0 |
| what‑it‑does | preservative | perfuming |
| irritancy, com. | 0, 0 |
| what‑it‑does | chelating | buffering |
| what‑it‑does | perfuming |