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SkinMedica Retinol Complex 0.5

Retinol Complex 0.5

Renews skin and diminishes the appearance of fine lines. Appropriate for all skin types pre-conditioned by using Retinol Complex 0.25 or another retinoid product.
Uploaded by: laurelm on

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Ingredient name what-it-does irr., com. ID-Rating
Water/Aqua/Eau solvent
Cetyl Ethylhexanoate emollient
Glycine Soja (Soybean) Oil emollient, perfuming 0, 3 goodie
Niacinamide cell-communicating ingredient, skin brightening, anti-acne, moisturizer/​humectant superstar
Polyacrylate-13
Caprylic/Capric Triglyceride emollient
Squalane skin-identical ingredient, emollient 0, 1 goodie
Retinol cell-communicating ingredient superstar
Palmitoyl Tripeptide-8 soothing goodie
Dunaliella Salina Extract
Magnolia Grandiflora Bark Extract antioxidant, antimicrobial/​antibacterial
Tocopherol antioxidant 0-3, 0-3 goodie
Tocotrienols
Ceramide 3 skin-identical ingredient goodie
Bisabolol soothing goodie
Phytosterols
Squalene skin-identical ingredient, antioxidant, emollient goodie
Tocopheryl Acetate antioxidant 0, 0
Oryza Sativa (Rice) Bran Wax (Oryza Sativa Cera)
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Polysorbate 20 emulsifying, surfactant/​cleansing 0, 0
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Cetyl Palmitate emollient 0, 0
Laureth-23 emulsifying, surfactant/​cleansing 0, 3
Trideceth-6 Phosphate emulsifying, surfactant/​cleansing
Sodium Hydroxide buffering
Dicaprylyl Ether emollient, solvent
Lauryl Alcohol emollient, viscosity controlling, emulsifying
Polyisobutene viscosity controlling
Dextran viscosity controlling
Potassium Sorbate preservative
Disodium EDTA chelating
Phenoxyethanol preservative
Ethylhexylglycerin preservative

SkinMedica Retinol Complex 0.5
Ingredients explained

Also-called: Aqua;Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

What-it-does: emollient

An odorless and colorless emollient ester (cetyl alcohol + ethylhexanoic acid) that gives a velvety and silky feel to the skin. It has great spreadability and a non-oily feel. It's a popular ingredient in makeup removers.

Also-called: Soybean Oil | What-it-does: emollient, perfuming | Irritancy: 0 | Comedogenicity: 3

The emollient plant oil coming from the soybean. It is considered to be a nice, cost-effective base oil with moisturizing properties. As for its fatty acid profile, it contains 48-59% barrier-repairing linoleic acid, 17-30% nourishing oleic acid and also some (4.5-11%) potentially anti-inflammatory linolenic acid

Niacinamide - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

A helper ingredient that functions as a film-forming polymer (big molecule from repeated subunits).

It usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. The three togeather have excellent thickening properties with remarkable emulsifying-stabilising abilities. They also have a nice silicone feel with glide-on spreading. 

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular. 

Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

Retinol - superstar
Also-called: Vitamin A, Form of Retinoids | What-it-does: cell-communicating ingredient
  • Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
  • It has to be converted in the skin to retinoic acid to work its magic
  • Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
  • A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
  • It makes skin less wrinkled, smoother, firmer and tighter
  • It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
  • Possible side effects and irritation are also much less than with retinoic acid
  • Do not use whilst pregnant
Read all the geeky details about Retinol here >>

Also-called: Neutrazen | What-it-does: soothing

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

We don't have description for this ingredient yet.

Ceramide 3 - goodie
Also-called: Ceramide NP | What-it-does: skin-identical ingredient

One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.

We wrote way more about ceramides at ceramide 1, so click here to know more.

Bisabolol - goodie
Also-called: Alpha-Bisabolol | What-it-does: soothing

It's one of the active parts of Chamomile that contains about 30% of bisabolol. It's a clear oily fluid that is used in skincare as a nice anti-inflammatory and soothing ingredient. 

We don't have description for this ingredient yet.

Squalene - goodie

Squalene is an oily liquid that originally comes from shark liver but luckily it can also be found in a couple of plant oils. Olive (0.6%), peanut (0.1%) and pumpkin (0.35%) oils contain it, though not in huge amounts. 

What contains more of it, is the sebum (the oily stuff) that our skin produces. About 13% of human sebum is squalene, which means that it’s an important skin-identical ingredient and NMF (natural moisturizing factor)

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

We don't have description for this ingredient yet.

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

A white, waxy emollient that gives "body" to skincare formulas. Comes from coconut or palm kernel oil. 

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 3

A white waxy solid that helps water and oil to mix nicely together (emulsifier). It is derived from the fatty alcohol lauryl alcohol by ethoxylating it and thus making the molecule a lot more water-soluble. In fact, Laureth-23 is mostly water-soluble acting as a solubilizer for dissolving small amounts of oily things into water-based formulas. 

We don't have description for this ingredient yet.

Also-called: lye | What-it-does: buffering

The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right. 

For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.  

What-it-does: emollient, solvent

A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel

We don't have description for this ingredient yet.

What-it-does: viscosity controlling

A polymer (big molecule from repeated subunits) that's used as a gloss improver for lipsticks and lipglosses. Its stickiness also helps lip products to stay on longer. 

Combined with polyacrylate-13 and polysorbate 20, it forms a very effective tickener-emulsifier trio.

What-it-does: viscosity controlling

We don't have description for this ingredient yet.

What-it-does: preservative

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4). 

But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does emollient
An odorless and colorless emollient ester that gives a velvety and silky feel to the skin. [more]
what‑it‑does emollient | perfuming
irritancy, com. 0, 3
The emollient plant oil coming from the soybean. It is rich in barrier repairing linoleic acid (48-59%) and is generally a good moisturizing oil. [more]
what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
A film forming polymer that usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. [more]
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0, 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
what‑it‑does cell-communicating ingredient
Vitamin A - the most proven anti-aging ingredient available OTC that can smooth wrinkles and make skin firmer. It might also be useful for acne-prone skin as it normalizes keratinization. [more]
what‑it‑does soothing
what‑it‑does antioxidant | antimicrobial/antibacterial
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does skin-identical ingredient
Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated.  [more]
what‑it‑does soothing
One of the active parts of Chamomile that is used in skincare as a nice anti-inflammatory and soothing ingredient. [more]
what‑it‑does skin-identical ingredient | antioxidant | emollient
Squalene is an oily liquid that originally comes from shark liver but luckily it can also be found in a couple of plant oils. Olive (0.6%), peanut (0.1%) and pumpkin (0.35%) oils contain it, though not in huge amounts. What contains more of it, is the sebum (the oily stuff) that our skin produces. [more]
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0, 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does emollient
irritancy, com. 0, 0
A white, waxy emollient that gives "body" to skincare formulas. Comes from coconut or palm kernel oil. 
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0, 3
A white waxy solid that helps water and oil to mix nicely together (emulsifier). It is derived from the fatty alcohol lauryl alcohol by ethoxylating it and thus making the molecule a lot more water-soluble. [more]
what‑it‑does emulsifying | surfactant/cleansing
what‑it‑does buffering
Lye - A solid white stuff that’s very alkaline and used in small amount to adjust the pH of the product.  [more]
what‑it‑does emollient | solvent
A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel. 
what‑it‑does emollient | viscosity controlling | emulsifying
what‑it‑does viscosity controlling
A polymer (big molecule from repeated subunits) that's used as a gloss improver for lipsticks and lipglosses. Combined with polyacrylate-13 and polysorbate 20, it forms a very effective tickener-emulsifier trio. [more]
what‑it‑does viscosity controlling
what‑it‑does preservative
A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast. [more]
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]