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SkinMedica Glypro Antioxidant Serum

Glypro Antioxidant Serum

This rejuvenating serum contains a glycolic compound that stimulates healthy skin renewal while diminishing the signs of aging. A potent blend of antioxidants in this serum also helps defend against harmful free radicals. With continued use, this silky serum works to hydrate and refresh skin, revealing a softer, smoother and more radiant complexion.
Uploaded by: maca on

Highlights

#alcohol-free #fragrance & essentialoil-free
Alcohol Free
Fragrance and Essential Oil Free

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water/Aqua/Eau solvent
Glycolic Acid exfoliant, buffering superstar
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Isononyl Isononanoate emollient
Phenyl Trimethicone emollient
Cyclomethicone emollient 0, 0
Cassia Angustifolia Seed Polysaccharide
Bis-Hydroxyethoxypropyl Dimethicone emollient
C14-22 Alcohols
C12-20 Alkyl Glucoside emulsifying, surfactant/​cleansing
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Camellia Oleifera Leaf Extract antioxidant, soothing goodie
Punica Granatum Extract
Glycyrrhiza Glabra (Licorice) Root Extract soothing, skin brightening superstar
Anthemis Nobilis Flower Extract soothing, perfuming goodie
Aloe Barbadensis Leaf Extract soothing, emollient, moisturizer/​humectant goodie
Stevia Rebaudiana Leaf/Stem Extract
Sodium Pca skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Urea skin-identical ingredient, moisturizer/​humectant goodie
Trehalose moisturizer/​humectant goodie
Polyquaternium-51 moisturizer/​humectant
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Xanthan Gum viscosity controlling
Cetearyl Alcohol emollient, viscosity controlling, emulsifying, surfactant/​cleansing 1, 2
Ceteareth-33 surfactant/​cleansing, emulsifying
Mannitol moisturizer/​humectant goodie
Cyclodextrin chelating
Yeast Extract (Faex Extract) moisturizer/​humectant goodie
Disodium Succinate surfactant/​cleansing
Olea Europaea (Olive) Leaf Extract perfuming
Polysilicone-11
Lecithin emollient, emulsifying goodie
Polyacrylate-13
Polyisobutene viscosity controlling
Polysorbate 20 emulsifying, surfactant/​cleansing 0, 0
Hexylene Glycol solvent, emulsifying, perfuming, surfactant/​cleansing 0-1, 0-2
Caprylyl Glycol moisturizer/​humectant, emollient
Triacetin antimicrobial/​antibacterial, solvent 0, 0
Ammonium Hydroxide buffering
Disodium Edta chelating
Ethylhexylglycerin preservative
Phenoxyethanol preservative
Potassium Sorbate preservative

SkinMedica Glypro Antioxidant Serum
Ingredients explained

Also-called: Aqua;Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Glycolic Acid - superstar
What-it-does: exfoliant, buffering
  • It’s the most researched AHA with the most proven skin benefits
  • It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
  • It can help skin’s own collagen production that results in firmer, younger skin
  • It can fade brown spots caused by sun damage or PIH
  • Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
  • Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
  • Slight stinging or burning with a stronger AHA product is normal
  • If your skin is very sensitive, rosacea prone choose rather a BHA or PHA product
Read all the geeky details about Glycolic Acid here >>

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: emollient

An emollient ester with a rich and creamy but non-greasy skin feel. It makes skin supple and protects dry skin. 

What-it-does: emollient

A silicone fluid that gives a nonoily, easy to spread emolliency to the formulas. It is also used as a water repellent additive and to reduce the tackiness and stickiness of other ingredients. It also imparts gloss, softness and better manageability to hair.

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

Cyclomethicone is not one type of silicone, but a whole mixture of them: it's a mix of specific chain length (4 to 7) cyclic structured silicone molecules. (There seems to be a confusion on the internet whether Cyclomethicone and Cyclopentasiloxane are the same. They are not the same, but Cyclopentasiloxane is part of the mixture that makes up Cyclomethicone). 

All the silicones in the Cyclomethicone mixture are volatile, meaning they evaporate from the skin or hair rather than stay on it. This means that Cyclomethicone has a light skin feel with none-to-minimal after-feel.  It also makes the formulas easy to spread and has nice emollient properties.

We don't have description for this ingredient yet.

What-it-does: emollient

We don't have description for this ingredient yet.

What-it-does: emulsion stabilising

A 100% vegetable origin emulsifier that usually comes to the formula with its buddy called C12-20 Alkyl Glucoside. The duo is trade-named Montanov L and works as an effective oil in water emulsifier. It creates ultra-soft, light texture, has excellent dermo-compatibility and is readily biodegradable.

Chemically speaking, it is a mixture of fatty alcohols with 14 to 22 carbon atoms in their fatty chains. 

A 100% vegetable origin emulsifier that usually comes to the formula with its buddy called C14-22 Alcohols. The duo is called Montanov L and two together help to create ultra-soft light formulas.

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

Also-called: tea oil camellia;Camellia Oleifera Leaf Extract | What-it-does: antioxidant, soothing

Camellia Oleifera is a type of green tea plant that's mostly known for the oil that comes from its seeds. As for the leaves, it has similar properties as the better known and more often used Camellia Sinensis leaves. You can read all the geeky details about green tea  and why it's awesome by clicking here, but in short, it has antioxidants and anti-inflammatory magic properties.

What-it-does: astringent

We don't have description for this ingredient yet.

Also-called: Licorice Root;Glycyrrhiza Glabra Root Extract | What-it-does: soothing, skin brightening

You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. It's sweet and yellow and not only used for licorice all sorts but it's also a skincare superstar thanks to two magic properties:

Nr. 1 magic property is that it has skin-lightening or to say it another way depigmenting properties. The most active part is called glabridin. The topical application (meaning when you put it on your face) of 0.5% glabridin was shown to inhibit UVB caused pigmentation of guinea pigs. Another study even suggested that licorice is more effective than the gold standard skin-lightening agent hydroquinone. All in all, licorice is considered to be one of the safest skin lightening agents with the fewest side effects.

Also-called: Roman Chamomile Flower Extract | What-it-does: soothing, perfuming

There are two primary types of Chamomile, the German and the Roman. Both has soothing properties, but the German one contains more anti-inflammatory actives (like chamazulene). The anti-inflammatory action of the Roman Chamomile is due to phenolic compounds and -  according to manufacturer info- it also has some nice skin toning properties.

Also-called: Aloe Leaf Extract | What-it-does: soothing, emollient, moisturizer/humectant

The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though  oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.

We don't have description for this ingredient yet.

Sodium Pca - goodie
Also-called: Sodium Pyrrolidone Carboxylic Acid;Sodium PCA | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium salt form of PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. 

Urea - goodie
Also-called: Carbamide | What-it-does: skin-identical ingredient, moisturizer/humectant

Yes, it's the thing that can be found naturally in pee. And in the skin. It is an awesome natural moisturizing factor, aka NMF.  NMFs are important components that help the skin to hold onto water and keep it plump, elastic and hydrated. Urea makes up about 7% of NMFs next to other things such as amino acids (40%), PCA (12%) or Lactate (12%).

What makes urea special, is that it is not only a simple moisturizer, but it is thought to be a "small-molecule regulator of epidermal structure and function" meaning that it has a bunch of extra biological activities. It acts as a mild keratolytic agent (some of its moisturizing action is thought to come from urea's ability to break down bonds in the protein called filaggrin and thus freeing up amino acids in the skin), enhances antimicrobial peptide expression and improves skin barrier function

Trehalose - goodie
What-it-does: moisturizer/humectant

A type of sugar that has water-binding properties and helps to keep your skin hydrated

What-it-does: moisturizer/humectant

A biocompatible copolymer (a big molecule that consists of more than one type of building blocks) that has the same structure as important cell membrane ingredient, phospholipid. It's a good skin moisturizer, leaves a silky, smooth feel on the skin and can help to reduce irritation caused by some not-so-nice ingredients (like surfactants).

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

What-it-does: emollient, viscosity controlling, emulsifying, emulsion stabilising, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

We don't have description for this ingredient yet.

Mannitol - goodie
What-it-does: moisturizer/humectant

A type of sugar molecule, that has water-binding properties and helps to keep your skin hydrated

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant

You probably know yeast from the kitchen where you put it into milk with a little sugar and then after a couple of minutes brownish bubbles form. That is the fungi fermenting the sugar

As for skin care, yeast contains beta-glucan that is a great soothing ingredient and also a mild antioxidant.  The yeast extract itself is a silky clear liquid that has some great moisturizing, skin protecting and film-forming properties on the skin. 

What-it-does: surfactant/cleansing

We don't have description for this ingredient yet.

Also-called: Olive Leaf | What-it-does: perfuming

We don't have description for this ingredient yet.

A type of silicone elastomer (rubber-like material with both viscosity and elasticity) whose major function is forming a nice film on the skin.

It is also cosmetically very elegant with a non-tacky, non-oily and smooth skin feel. It also works as a stable delivery system of active materials, has sebum absorption and control properties and upon application, it transforms into a matte appearance with a powdery after feel.

Lecithin - goodie
What-it-does: emollient, emulsifying

A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes

A helper ingredient that functions as a film-forming polymer (big molecule from repeated subunits).

It usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. The three togeather have excellent thickening properties with remarkable emulsifying-stabilising abilities. They also have a nice silicone feel with glide-on spreading. 

What-it-does: viscosity controlling

A polymer (big molecule from repeated subunits) that's used as a gloss improver for lipsticks and lipglosses. Its stickiness also helps lip products to stay on longer. 

Combined with polyacrylate-13 and polysorbate 20, it forms a very effective tickener-emulsifier trio.

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

What-it-does: solvent, emulsifying, perfuming, surfactant/cleansing | Irritancy: 0-1 | Comedogenicity: 0-2

Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable. 

Hexylene Glycol is also part a preservative blend named Lexgard® HPO, where it helps the effectiveness of current IT-preservative, phenoxyethanol

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

What-it-does: antimicrobial/antibacterial, solvent | Irritancy: 0 | Comedogenicity: 0

We don't have description for this ingredient yet.

What-it-does: buffering

We don't have description for this ingredient yet.

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

What-it-does: preservative

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4). 

But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does exfoliant | buffering
The most researched and well-known AHA exfoliant. It gently lifts off dead skin cells to reveal newer, fresher, smoother skin. In larger concentration (>10%) it's a proven collagen booster. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does emollient
An emollient ester with a rich and creamy but non-greasy skin feel. [more]
what‑it‑does emollient
A silicone fluid that gives a nonoily, easy to spread emolliency to the formulas. [more]
what‑it‑does emollient
irritancy, com. 0, 0
A mixture of 4 to 7 chain length cyclic silicones. It's a light, volatile ingredient that gives skin or hair a smooth feel and has emollient properties. [more]
what‑it‑does emollient
A 100% vegetable origin emulsifier that helps to create ultra-soft, light textures. [more]
what‑it‑does emulsifying | surfactant/cleansing
A 100% vegetable origin emulsifier that usually comes to the formula with its buddy called C14-22 Alcohols. The duo is called Montanov L and two together help to create ultra-soft light formulas.
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does antioxidant | soothing
A type of green tea that has antioxidants and anti-inflammatory properties. [more]
what‑it‑does soothing | skin brightening
You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. [more]
what‑it‑does soothing | perfuming
Roman Chamomile - thanks to its phenolic compound had some nice soothing and skin toning properties. It contains less anti-inflammatory actives than the German Chamomile. [more]
what‑it‑does soothing | emollient | moisturizer/humectant
The extract coming from the juice containing leaves of the Aloe vera plant with moisturizing, emollient and anti-inflammatory properties. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
The thing in the pee that is also a natural moisturizing factor (NMF) with mild keratolytic and strong skin moisturizing superpowers. [more]
what‑it‑does moisturizer/humectant
A type of sugar that has water-binding properties and helps to keep your skin hydrated. 
what‑it‑does moisturizer/humectant
A biocompatible copolymer with a similar structure to cell membrane ingredient, phospholipid. It's a good skin moisturizer and can also help to reduce irritation. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does emollient | viscosity controlling | emulsifying | surfactant/cleansing
irritancy, com. 1, 2
A super common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams. [more]
what‑it‑does surfactant/cleansing | emulsifying
what‑it‑does moisturizer/humectant
A type of sugar molecule, that has water-binding properties and helps to keep your skin hydrated.  [more]
what‑it‑does chelating
what‑it‑does moisturizer/humectant
A silky clear liquid that has great moisturizing, skin protecting and film-forming properties on the skin. [more]
what‑it‑does surfactant/cleansing
what‑it‑does perfuming
A type of silicone elastomer (rubber-like material with both viscosity and elasticity) whose major function is forming a nice film on the skin. [more]
what‑it‑does emollient | emulsifying
It's quite the multi-tasker: an emollient and water-binding ingredient but also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.  [more]
A film forming polymer that usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. [more]
what‑it‑does viscosity controlling
A polymer (big molecule from repeated subunits) that's used as a gloss improver for lipsticks and lipglosses. Combined with polyacrylate-13 and polysorbate 20, it forms a very effective tickener-emulsifier trio. [more]
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0, 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
what‑it‑does solvent | emulsifying | perfuming | surfactant/cleansing
irritancy, com. 0-1, 0-2
Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.  Hexylene Glycol is also part a preservative blend named Lexgard® [more]
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
what‑it‑does antimicrobial/antibacterial | solvent
irritancy, com. 0, 0
what‑it‑does buffering
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does preservative
A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast. [more]