Copper Amino Isolate Serum 5%
Ingredients overview
Highlights
Key Ingredients
Skim through
NIOD Copper Amino Isolate Serum 5%Ingredients explained
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
- GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
- It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
- It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
- It has significant anti-inflammatory and antioxidant effect
- There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
- It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
- There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
It's a pretty new anti-aging ingredient that is a "safe and pre-activated source of energy to feed aging skin cells".
It's part of an anti-aging complex trade named Neodermyl, where methylglucoside phosphate is combined with the essential amino acids proline, lysine and also copper. This complex is claimed to be able to increase the collagen I and III production of skin and even more surprisingly, also the elastin production. Both slow down with age and beeing able to boost the skin's own production of these super important proteins results in improved skin firmness and elasticity.
This is a very big deal, especially the elastin part, as there is not yet a clinically proven active ingredient that is able to boost the skin's own elastin production. There are also very few ones (think vitamin C, glycolic acid, and retinol) that are proven to boost collagen. The claims about Neodermyl are not yet confirmed in independent studies but the manufacturer did do some very convincing testing that showed a visible reduction of wrinkle depth and volume in just 15 days. If you are into anti-aging, this is a new active that might be worth a try.
An essential amino acid - mineral complex that is part of the pretty new anti-aging complex called Neodermyl. The manufacturer claims that the complex is able to boost skin's own collagen I and III as well as elastin production. Read more details at methylglucoside phosphate.
A helper ingredient that usually comes to the formula coupled with PEG-40 Hydrogenated Castor Oil. The two together work as surfactants and oil solubilizers. It's a non-sticky duo that works at low concentration and is often used to solubilize fragrance components into water-based formulas.
A mildly viscous, amber-colored liquid with fatty odor, made from Castor Oil and polyethylene glycol (PEG).
If it were a person, we’d say, it’s agile, diligent & multifunctional. It’s mostly used as an emulsifier and surfactant but most often it is used to solubilize fragrances into water-based formulas.
A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. It's often combined with IT-preservative, phenoxyethanol.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
It's a special "cross-linked" from of IT-moisturizer, hyaluronic acid (HA). Cross-linked means that "normal" HA pieces (1-2 million Da molecular weight) are chemically bound togeather to create a big, "infinite" mesh.
The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. This water filled crosslinked HA gel forms a smooth film on the skin and continuously delivers the bound water, so it gives long-term moisturizing benefits.
Btw, crosslinking HA was developed for dermal fillers (as crosslinking helps their longevity), and this guy is the topical version of FDA approved dermal filler called Hylan B gel. Smearing crosslinked version all over ourselves is a newish thing, and incoming evidence so far suggests that it's a great idea, even better than normal HA.
A very recent, 2016 research article compared the topical moisturizing effect of crosslinked HA (not Hylan B gel specifically, but something called Resilient HA or RHA), HMW-HA and LMW-HA and found that "TEWL (that is trans-epidermal water loss, the water that evaporates from the skin) was reduced by 27.8% with RHA, and by 15.6% with HMW HA, but increased by 55.5% with LMW HA." (You can read much more about HMW and LMW HA here in the geeky details section.)
All in all, we think Sodium Hyaluronate Crosspolymer is an awesome version of HA, probably superior to traditional versions, so be happy to spot it on the ingredient list.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A little helper ingredient that can boost the performance and enhance the delivery of active ingredients in a formula. It can penetrate deep layers of the skin helping actives to do the same.
It's especially useful to help active ingredients for self-tanning (DHA), anti-acne or skin-whitening to penetrate deeper and work better.
A nice odorless liquid used mainly as a superior solubilizer and efficacy booster for cosmetic active ingredients such as skincare bigshot vitamin C, self-tanning active DHA or the anti-acne gold standard, benzoyl peroxide.
Other than that it can also be used in hair care products where it gives a longer-lasting and more uniform coloring. According to a manufacturer, it might even prevent the formation of split ends.
A peptide consisting of four amino acids (arginine, glutamine, glycine, and proline). It's part of an active peptide complex called "Renaissance" that is supposed to increase skin compactness and firmness.
You can read more about "Renaissance" at Zinc Palmitoyl Nonapeptide-14.
A synthetic peptide containing 11 amino acids consisting of alanine, glutamine, glycine, isoleucine, lysine, proline and valine. It's part of an active peptide complex called "Renaissance" that is supposed to increase skin compactness and firmness.
You can read more about "Renaissance" at Zinc Palmitoyl Nonapeptide-14.
A peptide that is part of an active peptide complex called "Renaissance". It is supposed to increase skin compactness and firmness.
You can read more about "Renaissance" at Zinc Palmitoyl Nonapeptide-14.
It's part of a peptide complex called "Renaissance" whose name was inspired by "Re-birth for Skin". The manufacturer claims that his peptide powder is almost magic and can increase the ability of skin to renew, regenerate, redensify , rebuild and restore skin tissue.
The result is younger skin in 4 weeks with 38% more "skin compactness" or firmness. The peptide powder is supposed to be suitable for scar minimising as well.
A newish peptide with the promise of mimicking the effects of the skincare superstar, retinol (vitamin A) but without its negative side effects. Similar to retinol, Myristoyl Nonapeptide-3 is claimed to increase cell turnover and to promote the synthesis of collagen but without skin irritation or stinging.
To back up its claim, the German manufacturer did a so-called gene array screening test, where they examined the effect of the molecule on 96 skin-related genes. They did screening for both retinoic acid (the active form of retinol) and our guy Myristoyl Nonapeptide-3. They found that retinoic acid upregulates 21 of the 92 studied genes, and amongst those, 16 genes are also upregulated by Myristoyl Nonapeptide-3. So they trade named the molecule as Retinopeptide 189, as in a peptide that mimics the effects of retinoic acid.
To further prove their point, Symrise (the manufacturer) went ahead and did some ex-vivo testing (meaning testing on human skin explants). They compared a 0.1% retinoic acid solution with 5% and 10% Retinopeptide 189 cream and found that the 10% cream induces a significant increase (43%) in collagen-1 that is comparable to the effect of 0.1% retinoic acid (which performed even better with more than a 50% increase).
They also found that both retinoic acid 0.1% and Retinopeptide 189 5% cream increased epidermal cellular layers in the skin explants showing that both ingredients can increase cell turnover, however retinoic acid did significantly better both in active effects as well as side effects.
Unfortunately, there are currently no in-vivo test results (at least with could not find any), so if you prefer the tried and true, stick with retinol. However, if you are the adventurous type or if your skin is sensitive and cannot tolerate retinoids, Myristoyl Nonapeptide-3 is a promising alternative.
A chemically chopped up version of wheat protein that consists mainly of amino acids (the building blocks), peptides (a couple of amino acids together), and proteins (lots of amino acids together).
It has moisturizing and film-forming properties and might be able to counteract the irritating effects of cleansing agents in cleansers and shampoos. It can also condition and repair damaged hair leaving it soft, silky and smooth.
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens.
A helper ingredient that usually comes to the formula coupled with PEG-40 Hydrogenated Castor Oil. The two together work as surfactants and oil solubilizers. It's a non-sticky duo that works at low concentration and is often used to solubilize fragrance components into water-based formulas.
A mildly viscous, amber-colored liquid with fatty odor, made from Castor Oil and polyethylene glycol (PEG).
If it were a person, we’d say, it’s agile, diligent & multifunctional. It’s mostly used as an emulsifier and surfactant but most often it is used to solubilize fragrances into water-based formulas.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A 100% plant derived, natural (Ecocert approved) multi-functional ingredient that has emollient and moisturizing properties, can work as a co-emulsifier (meaning that next to other emulsifiers it can help water and oil to mix) and even more importantly has a strong antimicrobial activity.
Thanks to this last thing, it allows a lower percentage of traditional preservative or it might even be able to completely replace them.
A naturally occurring floral component with a delicate scent that can mask the odor of other raw materials but is not noticeable in the final product. It also has remarkable antimicrobial and preservative boosting abilities and can help to create "preservative-free" formulas.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. It's often combined with IT-preservative, phenoxyethanol.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
You may also want to take a look at...
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient | soothing | antioxidant |
| what‑it‑does | solvent |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | preservative | antimicrobial/antibacterial |
| what‑it‑does | preservative |
| what‑it‑does | solvent |
| what‑it‑does | skin-identical ingredient | antioxidant | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | solvent | viscosity controlling |
| what‑it‑does | solvent | moisturizer/humectant | perfuming |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | solvent | moisturizer/humectant |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | preservative |
| what‑it‑does | perfuming | solvent |
| what‑it‑does | preservative |
| what‑it‑does | preservative | antimicrobial/antibacterial |
| what‑it‑does | preservative |