Comprehensive Retinol 0.3% Night Serum
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Neostrata Comprehensive Retinol 0.3% Night SerumIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
A type of silicone elastomer (rubber-like material with both viscosity and elasticity) whose major function is forming a nice film on the skin.
It is also cosmetically very elegant with a non-tacky, non-oily and smooth skin feel. It also works as a stable delivery system of active materials, has sebum absorption and control properties and upon application, it transforms into a matte appearance with a powdery after feel.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A nice, multi-functional helper ingredient that's especially useful in sunscreens. It can solubilize some commonly used UV-filters like Oxybenzone or Avobenzone and it can also help to increase the SPF rating of sunscreens. It's also cosmetically elegant, has excellent spreadability and a pleasant, moisturizing skin feel. Oh, and according to Wikipedia, it even helps to stabilize famously unstable UVA-filter, Avobenzone.
An amino acid sugar that can be found in the skin and does there good and important things. One of them is that it's a precursor for the biosynthesis of superstar moisturizer, hyaluronic acid. So acetyl glucosamine itself is also an important skin-identical ingredient and natural moisturizing factor.
But that is not all, acetyl glucosamine has two other great properties proved by double-blind clinical trials. First, it's a promising ingredient against wrinkles: 2% can improve wrinkles, particularly in the eye area.
Second, the same amount can also fade - always stubborn - brown spots. (Do not expect magic, though - the photos from the study show the difference after 8 weeks of daily use. The difference is visible, but not that big. It's always good to have realistic expectations. :)) Combined with skincare superstar niacinamide the duo is synergistic and is more effective at improving hyperpigmentation, so if you are after the skin-lightening benefit look out for products that contain both.
An odorless, slightly yellowish powder that's used as a polymer microsphere (a tiny little ball from repeated subunits). It gives products an elegant, silky texture and better slip. It can also scatter light to blur fine lines while letting enough light through so that the skin still looks natural.
A white powdery thing that's the major component of glass and sand. In cosmetics, it’s often in products that are supposed to keep your skin matte as it has great oil-absorbing abilities. It’s also used as a helper ingredient to thicken up products or suspend insoluble particles.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.
There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.
As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%), it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.
- Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
- It has to be converted in the skin to retinoic acid to work its magic
- Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
- A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
- It makes skin less wrinkled, smoother, firmer and tighter
- It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
- Possible side effects and irritation are also much less than with retinoic acid
- Do not use whilst pregnant
A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing.
Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former. Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
A light, velvety, unique skin feel liquid that is a good solvent and also makes the skin feel nice and smooth (aka emollient). It's often used in makeup products mixed with silicones to give shine and slip to the product. It's also great for cleansing dirt and oil from the skin as well as for taking off make-up.
A silicone emulsifier that helps water and silicone oils to mix nicely together. It can also be used together with plant oil + silicone oil mixtures.
There is not much info about this guy in itself other than it helps to thicken up products and stabilize oil-in-water emulsions. It usually comes to the formula as part of some thickener complex. For example, coupled with isohexadecane and polysorbate 80, the trio forms an instant gel upon mixing with water.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
It's one of the active parts of Chamomile that contains about 30% of bisabolol. It's a clear oily fluid that is used in skincare as a nice anti-inflammatory and soothing ingredient.
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
This long-named, polymer molecule (big molecule from repeated subunits) is a helper ingredient that's good at emulsifying and stabilizing oils into water-based formulas. It also acts as a thickening and gelling agent that creates nice, non-sticky and supple textures. It works over a very wide pH range (3-12) and can be used to thicken up low-ph formulas, such as exfoliants. Its recommended used range is 0.3-3%.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. It's often combined with IT-preservative, phenoxyethanol.
Ci 19140 or Tartrazine is a super common colorant in skincare, makeup, medicine & food. It’s a synthetic lemon yellow that's used alone or mixed with other colors for special shades.
FDA says it's possible, but rare, to have an allergic-type reaction to a color additive. As an example, it mentions that Ci 19140 may cause itching and hives in some people but the colorant is always labeled so that you can avoid it if you are sensitive.
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| what‑it‑does | solvent |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | solvent |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | solvent |
| what‑it‑does | skin-identical ingredient | skin brightening |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | buffering |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emulsifying |
| what‑it‑does | viscosity controlling |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | chelating |
| what‑it‑does | viscosity controlling |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | preservative |
| what‑it‑does | preservative | antimicrobial/antibacterial |
| what‑it‑does | colorant |