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Khadi Retinol 2.5% Serum

Retinol 2.5% Serum

Professional anti- aging formula with hyaluronic acid and Vitamin E.
Uploaded by: thrishamirzashaik on

Khadi Retinol 2.5% Serum
Ingredients explained

Also-called: Form of Retinoids | What-it-does: cell-communicating ingredient | Irritancy: 1-3 | Comedogenicity: 1-3

It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the queen being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince William, two steps away from the throne. Retinyl palmitate will be then little Prince George, quite far (3 steps) away from the throne. 

By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:

  • It’s naturally in our skin and behaves there like a sponge
  • It can bind up to 1000 times its own weight in water
  • It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
  • High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
  • Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
  • Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
  • Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
Read all the geeky details about Hyaluronic Acid here >>

Also-called: Part of Olivem 1000 | What-it-does: emulsifying

An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000. 

Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles as an active ingredient with significant moisturizing, barrier-repairing and soothing properties.

Also-called: Part of Olivem 1000 | What-it-does: emulsifying

An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>

Also-called: Form of Vitamin C, SAP | What-it-does: antioxidant, anti-acne

The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.

Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. One solution is to create stable derivatives that can be absorbed into the skin, convert there to AA and do all the magic AA is proven to do (which is being an antioxidant, a collagen booster, and a skin brightener).

Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

Also-called: Wheat Germ Oil;Triticum Vulgare Germ Oil | What-it-does: emollient, moisturizer/humectant

We don't have description for this ingredient yet.

Also-called: Hamamelis Virginiana Extract | What-it-does: soothing, antioxidant, antimicrobial/antibacterial, astringent

Witch hazel is a smallish tree (up to 5m) that's native to North-America, has nice yellow flowers and is similar to the hazelnut bush (hence the name).  

As for skincare, it's loaded with active components that have a bunch of magic properties, like astringent, anti-inflammatory, antioxidant and anti-bacterial. It's also a well-known vasoconstrictor (it makes the blood vessels narrower) and promotes the healing of broken skin by tightening up the skin proteins and thus creating a protective covering.

Also-called: Aloe Leaf Extract;Aloe Barbadensis Leaf Extract | What-it-does: soothing, emollient, moisturizer/humectant

The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though  oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

Also-called: Jojoba Oil;Simmondsia Chinensis Seed Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0-2

Jojoba is a drought resistant evergreen shrub native to South-western North America. It's known and grown for jojoba oil, the golden yellow liquid coming from the seeds (about 50% of the weight of the seeds will be oil).  

At first glance, it seems like your average emollient plant oil: it looks like an oil and it's nourishing and moisturizing to the skin but if we dig a bit deeper, it turns out that jojoba oil is really special and unique: technically - or rather chemically - it's not an oil but a wax ester (and calling it an oil is kind of sloppy). 

Also-called: Tea Tree Oil, TTO;Melaleuca Alternifolia Leaf Oil | What-it-does: soothing, anti-acne, antioxidant, antimicrobial/antibacterial, perfuming

The famous tea tree oil. One of the best known essential oils which comes from Australia where it has been used for almost 100 years for its antiseptic and anti-inflammatory actions. Legend has it that the medicinal benefits of the oil were considered so important that Australian soldiers were supplied with some tea tree oil in their World War II military kit.

Similar to other essential oils, tea tree oil is a very complex chemical mixture consisting of about 100 components, the major ones being terpinen-4-ol (40%), γ-Terpinene (23%) and α-Terpinene (10%). Terpinen-4-ol is considered to be the main active component but as a great article in Clinical Microbiology Reviews states "while some TTO components may be considered less active, none can be considered inactive" and most components contribute to TTO's strong antibacterial, antiviral and antifungal effects

Also-called: Green Tea;Camellia Sinensis Leaf Extract | What-it-does: antioxidant, soothing
  • Green tea is one of the most researched natural ingredients
  • The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
  • There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
  • Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
  • Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis
Read all the geeky details about Camellia Sinensis Leaf Extract here >>

Also-called: Moringa Seed Oil | What-it-does: emollient

The oil coming from the seeds of the Moringa tree, a big white-flowered tree native to India. It's a yellow oil similar to olive oil. It's rich in nourishing and moisturizing fatty acid, oleic (75%) and also contains behenic acid (up to 8%) that makes moringa very stable and gives the oil a long shelf life

It blends easily with essential oils and can also help to stabilize scents so it's a popular oil in the perfume industry. 

Also-called: Gotu Kola, Tiger Grass;Centella Asiatica Extract | What-it-does: soothing, antioxidant, moisturizer/humectant

Centella Asiatica - or gotu kola as normal people call it  - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.

Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).

Also-called: Equisetum Arvense Extract | What-it-does: soothing, emollient, astringent

We don't have description for this ingredient yet.

Also-called: Rosemary Leaf Oil;Rosmarinus Officinalis Leaf Oil | What-it-does: antioxidant, antimicrobial/antibacterial

The essential oil coming from the leafs of the lovely herb, rosemary. It contains several fragrant components, including the well-known irritant, camphor (around 15%). It has a nice smell, is a potent antioxidant and it's also an antimicrobial agent.

If your skin is sensitive, it's probably a good idea to avoid it.

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

This ingredient name is not according to the INCI-standard. :( What, why?!

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

You may also want to take a look at...

what‑it‑does cell-communicating ingredient
irritancy, com. 1-3, 1-3
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
what‑it‑does emulsifying
Part of Olivem 1000, a natural emulsifier duo that is known for forming biomimetic liquid crystal structures. It doubles as an active ingredient with barrier repairing and soothing properties. [more]
what‑it‑does emulsifying
An ester coming from sorbitol and the fatty acids of olive oil. It often comes to the formula coupled with Cetearyl Olivate and the two together help water and oil to blend (emulsifier). It's a natural and Ecocert approved duo.
what‑it‑does antioxidant | anti-acne
The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it. Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. [more]
what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
what‑it‑does emollient | moisturizer/humectant
what‑it‑does soothing | antioxidant | antimicrobial/antibacterial
With Hazel - loaded with active components (hamamelitannin, catechins, gallic acid) that have astringent, anti-inflammatory, antioxidant or anti-bacterial properties. Also well-known vasoconstrictor and promotes skin healing. [more]
what‑it‑does soothing | emollient | moisturizer/humectant
The extract coming from the juice containing leaves of the Aloe vera plant with moisturizing, emollient and anti-inflammatory properties. [more]
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does emollient
irritancy, com. 0, 0-2
Jojoba oil - a wax ester (chemically not a real oil), that's very similar to human sebum. It's uniquely excellent at helping the skin with its protective barrier and helping it to stay moisturized. [more]
what‑it‑does soothing | anti-acne | antioxidant | antimicrobial/antibacterial | perfuming
The famous tea tree oil. One of the best known essential oils which comes from Australia where it has been used for almost 100 years for its antiseptic and anti-inflammatory actions. [more]
what‑it‑does antioxidant | soothing
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
what‑it‑does emollient
An emollient plant oil that is rich in nourishing and moisturizing fatty acid, oleic (75%) and also contains behenic acid (up to 8%) that makes moringa very stable and gives the oil a long shelf life. [more]
what‑it‑does soothing | antioxidant | moisturizer/humectant
Centella Asiatica - or gotu kola as normal people call it  - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema. Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits [more]
what‑it‑does soothing | emollient
what‑it‑does antioxidant | antimicrobial/antibacterial
The essential oil coming from the leafs of rosemary. It has a nice smell, is a potent antioxidant and it's also an antimicrobial agent. Contains several fragrant components, including potential skin irritant, camphor (around 15%).
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]