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Josh Rosebrook Active Infusion Oil

Active Infusion Oil

This micronutrient, fatty acid rich, plant oil blend absorbs quickly and cushions the delivery of the actives into the skin while antioxidant rich, in-house made herb and mushroom extracts offer concentrated phytonutrients to help support, regenerate and protect skin structure and luminosity.
Uploaded by: hhesver on

Josh Rosebrook Active Infusion Oil
Ingredients explained

Also-called: Jojoba Oil;Simmondsia Chinensis Seed Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0-2

Jojoba is a drought resistant evergreen shrub native to South-western North America. It's known and grown for jojoba oil, the golden yellow liquid coming from the seeds (about 50% of the weight of the seeds will be oil).  

At first glance, it seems like your average emollient plant oil: it looks like an oil and it's nourishing and moisturizing to the skin but if we dig a bit deeper, it turns out that jojoba oil is really special and unique: technically - or rather chemically - it's not an oil but a wax ester (and calling it an oil is kind of sloppy). 

So what the heck is a wax ester and why is that important anyway? Well, to understand what a wax ester is, you first have to know that oils are chemically triglycerides: one glycerin + three fatty acids attached to it. The fatty acids attached to the glycerin vary and thus we have many kinds of oils, but they are all triglycerides. Mother Nature created triglycerides to be easily hydrolyzed (be broken down to a glycerin + 3 fatty acid molecules) and oxidized (the fatty acid is broken down into small parts) - this happens basically when we eat fats or oils and our body generates energy from it.

Mother Nature also created wax esters but for a totally different purpose. Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Wax esters are on the outer surface of several plant leaves to give them environmental protection. 25-30% of human sebum is also wax esters to give us people environmental protection. 

So being a wax ester results in a couple of unique properties: First, jojoba oil is extremely stable. Like crazy stable. Even if you heat it to 370 C (698 F) for 96 hours, it does not budge. (Many plant oils tend to go off pretty quickly). If you have some pure jojoba oil at home, you should be fine using it for years. 

Second, jojoba oil is the most similar to human sebum (both being wax esters), and the two are completely miscible. Acne.org has this not fully proven theory that thanks to this, jojoba might be able to "trick" the skin into thinking it has already produced enough sebum, so it might have "skin balancing" properties for oily skin.

Third, jojoba oil moisturizes the skin through a unique dual action: on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer; on the other hand, it absorbs into the skin through pores and hair follicles then diffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple.

On balance, the point is this: in contrast to real plant oils, wax esters were designed by Mother Nature to stay on the surface and form a protective, moisturizing barrier and jojoba oil being a wax ester is uniquely excellent at doing that.

Also-called: Sunflower Oil;Helianthus Annuus Seed Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more  we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.

It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.

Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.

It's also loaded with fatty acids (mostly linoleic (50-74%)  and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil

Truth be told, there are many great plant oils and sunflower oil is definitely one of them.

Also-called: Dog-Rose Seed Oil, Rosehip Seed Oil;Rosa Canina Seed Oil | What-it-does: emollient

The oil coming from the seeds of dog-rose, a wild rose species native to Europe, northwest Africa and western Asia. It's a nice emollient, moisturizing plant oil loaded with skin-nourishing fatty acids (linoleic acid - 51%, linolenic acid - 19% and oleic acid - 20%). 

If you start to dig a bit deeper into the rosehip oil topic, you will soon see that there are lots of species of rose, and it's all a bit confusing to know what the differences and similarities between the oils of the different roses are. As far as our research can tell, here is the gist.

In skincare two major types of rosehip oil are used:

1. Rosa Rubiginosa that is a synonym for Rosa Eglanteria and for Rosa Mosqueta. We will call it RR from now on. 

2. Rosa Canina, or RC

The oil content and composition of RR and RC is similar, but there are some differences: RR contains 8% of oil, while RC contains a bit more, 10%. However, the quality of RR oil seems to be a bit better: it contains 78% essential unsaturated fatty acids while RC contains only 71%. Also, the linoleic-oleic ratio of RR is better (3.3 vs 2.5) that might be important if your skin is acne-prone (as linoleic acid is good for acne and oleic is not). 

There is one more important thing to mention: RR oil is famous for containing the miracle active, tretinoin. Though Wikipedia puts RR and RC oil under the same article called as Rose hip seed oil, the referenced research about tretinoin content examines only Rosa Rubiginosa. We looked for a research paper explicitly stating that Rosa Canina also contains tretinoin, but could not find one, so we can neither deny nor confirm it. What we could find is a paper mentioning the tocopherols (vitamin E) and carotenoids (pro-vitamin A) content of Rosa Canina oil that gives it some nice antioxidant properties.

All in all, it is a great emollient plant oil with great fatty acids beneficial for any skin type. 

Also-called: Form of Vitamin C, Ascorbyl Isotetrapalmitate, Ascorbyl Tetraisopalmitate, ATIP | What-it-does: antioxidant, skin brightening

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it in excruciating detail.

So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it ATIP in short).

It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown. In addition, vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in the case of ATIP, it's in-vitro and done by an ingredient supplier.

With this context in mind let's see what ATIP might be able to do. First, it is stable (if pH < 5), easy to formulate and a joy to work with for a cosmetic chemist.

Second, because it's oil-soluble, its skin penetration abilities seem to be great. So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the skin (that is usually important to do some anti-aging work). There is also in-vitro data showing that it converts to AA in the skin. 

Third, ATIP seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by more than 80% in human melanoma cell cultures.

So this all sounds really great, but these are only in-vitro results at this point. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% ATIP. The authors theorized that the 10% AA is released slowly from the silicon delivery system and probably stays in the upper layer of the skin to give antioxidant benefits, while ATIP penetrates more rapidly and deeply and gives some wrinkle-reducing benefits. The study was a small (10 patients), double-blind experiment, and the formula did show some measurable anti-aging results. However, it is hard to know how much pure vitamin C or ATIP can be thanked.

Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet).

Also-called: Hemp Oil;Cannabis Sativa Seed Oil | What-it-does: emollient

We don't have description for this ingredient yet.

A little helper ingredient that can boost the performance and enhance the delivery of active ingredients in a formula. It can penetrate deep layers of the skin helping actives to do the same.

It's especially useful to help active ingredients for self-tanning (DHA), anti-acne or skin-whitening to penetrate deeper and work better.

Also-called: Granactive Retinoid, HPR, Form of Retinoids | What-it-does: cell-communicating ingredient

Hydroxypinacolone Retinoate (HPR) is the newest member of the "royal family of skincare" (see who is who on this cool retinoids family tree), the retinoid family. The queen of the family is the FDA-approved anti-aging superstar, retinoic acid, aka tretinoin and HPR seems to be a gentle but influential sister princess to the queen.

Good to know: the trade name of HPR is Granactive Retinoid. The manufacturer produces it as 10% active and 90% solvent called dimethyl isosorbide. When a product claims 2% Granactive Retinoid, it means 0.2% Hydroxypinacolone Retinoate (and 1.8% dimethyl isosorbide) on the ingredient list. 

It's a so-called retinoic acid ester, meaning that it's directly related to retinoic acid. If you've already read our description about retinol or retinyl palmitate, you know that the active ingredient our skin cells can interpret is retinoic acid. Other forms of retinoids have to be converted by our metabolic machinery to do something. That's not the case with HPR.  It binds directly to the retinoid receptors of the skin cells to work its skincare magic. 

The big promise of HPR is that it's similarly active as retinoic acid (no conversion needed, remember) but without the irritation. According to the manufacturer's tests, 24 hours of an occlusive patch with 0.5% HPR resulted in significantly lower irritation than 0.5% retinol.  Also, there was a "dramatic reduction of lines and wrinkles" after applying 0.2% HPR around the eyes twice a day for 14 days.

These results sound sooo promising that we don't blame you if you wanna run out right now and get an HPR formula to slather on your face.  But, before you do, you have to know that the info we have about HPR at the moment is mainly from the manufacturer, whose tests may or may not be accurate or properly designed (such as controlled, double-blind and conducted on an appropriate number of people). 

As HPR is pretty new there isn't that much independent research we could find yet. We found two Italian studies both examining the efficacy of HPR combined with other things (retinol in both cases, and papain in one of them) for the treatment of acne. Both studies found the formulas effective but they contained other things too, so it's hard to judge how well HPR did.

Regarding anti-aging, there is a pretty recent, Estee Lauder sponsored study that compared the in-vitro (not on real human beings but on skin models) collagen-boosting effectiveness of Hydroxypinacolone Retinoate, tretinoin, good old retinol and retinyl palmitate (RP). The results are pretty encouraging showing that  "HPR had greater levels of gene transcription than retinol and RP (RP) at the same concentrations ... however, HPR did not achieve gene transcription levels of ATRA (tretinoin)."  But, a much higher dose might be tolerated from HPR and the highest dose of HPR out-performed tretinoin. Pretty encouraging, though we are very much waiting for a study to confirm all this on real human beings.  

Bottom line: We are really happy to see some innovation happening with retinoids, and we think Hydroxypinacolone Retinoate is a super promising rising star, but it’s not fully proven yet. If you are someone who likes to experiment and try out the newest things, grab your running shoes and try some HPR containing serum now (see product list below :)). If you like the tried and true, however, stick to retinol and tretinoin for now and re-examine the question in a couple of years when (hopefully) more research will be available. 

Are you into Retinoids? Read our shiny description about other members of the retinoid family: 

Also-called: Vitamin E;Tocopherol | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

Also-called: Sea Buckthorn Berry Oil;Hippophae Rhamnoides Fruit Oil | What-it-does: antioxidant, emollient

The oil coming from the pulp of the sea buckthorn berry. It has a pretty unique fatty acid composition: 65% is a combination of the rare Omega-7, aka palmitoleic acid and the more common palmitic acid. Fatty acids give the oil nice moisturizing and skin-protecting abilities. 

But that's not all the goodness of sea buckthorn oil. It contains antioxidant superstar, Vitamin E (in multiple forms), antioxidant (and orange color giving) pigments beta-carotene and lycopene, as well as skin-soothing and replenishing beta-sitosterol

Btw, used undiluted, it will make your skin orange. 

All in all, a goodie emollient plant oil. 

*Calendula - goodie
Also-called: Calendula Extract, Marigold Extract;Calendula Officinalis Extract | What-it-does: soothing, antioxidant

The extract coming from the popular garden plant Calendula or Marigold. It's used traditionally as a skin-repairing and soothing plant extract

Click here to read more at the calendula flower extract

*Green Tea - superstar
Also-called: Green Tea;Camellia Sinensis Leaf Extract | What-it-does: antioxidant, soothing
  • Green tea is one of the most researched natural ingredients
  • The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
  • There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
  • Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
  • Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis
Read all the geeky details about Camellia Sinensis Leaf Extract here >>

This ingredient name is not according to the INCI-standard. :( What, why?!

We don't have description for this ingredient yet.

Also-called: Marula Seed Oil;Sclerocarya Birrea Seed Oil | What-it-does: emollient

If you have an interest in elephants and Africa, you have probably heard of elephants getting drunk from the fruit of the Marula tree. Though this seems to be only a legend, what is true is that the Marula fruit is really nice (and elephants do love to eat it) and there is a stone in it with several oil-rich kernels inside. 

So the Marula oil - similar to many other plant oils - is a really nice nourishing and moisturizing oil that can improve skin hydration and smoothness and it can even reduce skin redness. It's traditionally used in South Africa to massage babies with and as a body lotion for face, feet, and hands.

As for its composition, it's loaded with skin goodies: it's very rich in fatty acids, including oleic (73%), palmitic (15%), and linoleic (9%) acids. It also contains some natural antioxidants, including Vitamin E and the oil shows an outstanding oxidative stability. 

If you have dry skin that needs some pampering, Marula oil is a good choice. 

Also-called: Ashwagandha;Withania Somnifera Extract

We don't have description for this ingredient yet.

Also-called: Dandelion Leaf Extract;Taraxacum Officinale Leaf Extract

The extract coming from the leaves of dandelion. It's a folkloric medicine for the treatment of liver and kidney disorders and we could find several studies confirming its liver-protecting, "detoxifying" effect.

What we could not find is information on what dandelion is doing in cosmetic products. Our best info is that it "enhances the clarity of skin" by helping the detoxification of the liver (though we have to admit we are a bit sceptical about this).  

*Turmeric - goodie
Also-called: Turmeric Root Extract;Curcuma Longa Root Extract | What-it-does: antioxidant, soothing, skin brightening, perfuming

Turmeric is the yellow spice you probably know from curry and Indian food. It's also a traditional herbal medicine used in Ayurveda for its bunch of anti-something magic abilities including being anti-inflammatory, antimicrobial, antioxidant and anticarcinogenic. 

As for turmeric and skincare, we have good news: studies show that the root extract and its main biologically active component, curcumin can do multiple good things for the skin. Thanks to its anti-inflammatory and antimicrobial activity, it shows some promise for acne-prone skin and a small study from 2013 showed that it might be able to regulate sebum production

It's also a potent antioxidant and skin-brightening agent so it often shows up in anti-aging and/or radiance-boosting products. 

A colorless liquid used in small amounts as a so-called masking ingredient, meaning it can hide the natural not-so-nice smell of other cosmetic ingredients. It has a nice rose-like scent and can be found in several essential oils such as rose, neroli or geranium. It also has some antimicrobial activity and can boost the performance of traditional preservatives.

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

You may also want to take a look at...

what‑it‑does emollient
irritancy, com. 0, 0-2
Jojoba oil - a wax ester (chemically not a real oil), that's very similar to human sebum. It's uniquely excellent at helping the skin with its protective barrier and helping it to stay moisturized. [more]
what‑it‑does emollient
irritancy, com. 0, 0
Sunflower Oil - it's a great emollient that protects & enhances the skin barrier. [more]
what‑it‑does emollient
The oil coming from dog-rose. A nice emollient, moisturizing plant oil loaded with skin-nourishing fatty acids (linoleic acid - 51%, linolenic acid - 19% and oleic acid - 20%). [more]
what‑it‑does antioxidant | skin brightening
A stable, oil-soluble form of Vitamin C, that might have (in-vitro results) all the magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener). [more]
what‑it‑does emollient
what‑it‑does solvent | viscosity controlling
A helper ingredient that can boost the performance and enhance the delivery of active ingredients. It can penetrate deep layers of the skin helping actives to do the same. [more]
what‑it‑does cell-communicating ingredient
The newest member of the retinoid family. Its big promise is that it's similarly active as retinoic acid but without the irritation. For now, it's a very promising but not properly proven active both for anti-aging and acne treatment. [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does antioxidant | emollient
Sea buckthorn berry oil - contains rare omega-7 fatty acid, antioxidants, and skin-soothing plant sterols. A nice moisturising and skin protecting oil. [more]
what‑it‑does soothing | antioxidant
Marigold extract - used traditionally as a skin-repairing and soothing plant extract.  [more]
what‑it‑does antioxidant | soothing
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
what‑it‑does emollient
Marula Oil - a really nice nourishing and moisturizing oil that can improve skin hydration and smoothness and it can even reduce skin redness. It's a rich source of fatty acids (mainly oleic - 73%) and antioxidant vitamin E. [more]
Dandelion Extract - a folkloric medicine for the treatment of liver and kidney disorders. It's unclear what it does in a cosmetic product. [more]
what‑it‑does antioxidant | soothing | skin brightening | perfuming
Turmeric Root Extract that has nice anti-inflammatory, antioxidant and skin-brightening properties. [more]
A colorless liquid used in small amounts as a so-called masking ingredient, meaning it can hide the natural not-so-nice smell of other cosmetic ingredients.  [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]