EGF Limpid Foam Cleanser
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Dr HEDISON EGF Limpid Foam CleanserIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
A 14 carbon length fatty acid that can be naturally found in nutmeg, palm kernel oil, coconut oil and butter fat. It's used as a foam building cleansing agent. Paula Begoun writes that it can be a bit drying to the skin.
A soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge). It also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
The famous or rather infamous SLS (not to be confused with SLES). It is a cleansing agent known for being too good at the job and potentially irritating the skin. But, on the positive side, it can produce copious, creamy and luxurious foam compared to the more gentle and thus nowadays much more commonly used Sodium Laureth Sulfate.
In fact, SLS is so good at irritating the skin that it is very commonly used in dermatological studies just for that. It is a so-called "primary irritant", a substance that irritates the skin in one go (without prior sensitization) but doesn't do any other big harm (such as being carcinogenic or systematically toxic - those claims are not true). Also, the formula can greatly influence the irritating potential of SLS, and mixing it with other cleaning agents makes it milder.
If it's not in a cleanser, it works as an emulsifier or even as a penetration enhancer for active materials.
Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.
Hexylene Glycol is also part a preservative blend named Lexgard® HPO, where it helps the effectiveness of current IT-preservative, phenoxyethanol.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
It’s probably the most common cleansing ingredient of all. It’s usually the Chief Bubble Officer responsible for big bubbles in cleansing products through the foam it creates is a bit airy and loose and not as dense and luxurious as the foam created by infamous SLS.
As for mildness, it goes somewhere in the middle. It’s often confused with sodium lauryl sulfate (SLS), but they are absolutely not the same. The SLES molecule has a bigger water-soluble head part that makes it milder and much less irritating. It is considered absolutely ok in the amount used in cosmetic products, though if you are looking for a mild facial cleanser, you have better chances with a formula without SLES. For an average shower gel? SLES works just fine.
It's a very alkaline stuff that helps to set the pH of the cosmetic formula to be just right. It's similar to the more often used sodium hydroxide and pretty much the same of what we wrote there applies here too.
A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).
We don't have description for this ingredient yet.
A so-called diester created from two stearic acid molecules and an ethylene glycol molecule. Its main thing is being an opacifier and pearling agent in cleansing products making them white and glossy. It can also give body to creams and emulsions.
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
We don't have description for this ingredient yet.
A chelating agent that helps to preserve cosmetic products by neutralizing the metal ions (especially iron) in the formula (that usually get into there from water). Its special thing is that it also acts as a biostatic and fungistatic agent and remains active even at high pH.
It is often coupled with antimicrobial glycols (such as propanediol) to create a "preservative free preservative system" for cosmetic products.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together.
It's often paired with glyceryl stearate - the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
Sh-Oligopeptide-1 is the famous molecule, which is also called Epidermal Growth Factor or EGF. Chemically speaking, Growth Factors are largish peptides or smallish proteins, or to put it in another way, medium-length amino acid sequences (EGF consists of 53 amino acids). Biologically speaking, Growth Factors are cellular signal molecules that can stimulate cell growth, proliferation, healing and/or differentiation.
There are lots of Growth Factors and EGF is just one of them. The topic of "Growth Factors and skincare" is a big, confusing and controversial one and we will try our best to summarize the story for you, including the pros and the cons.
EGF is a special snowflake when it comes to skincare as it was the first Growth Factor that made its way into cosmetic products and it is also the most common one. The American biochemist, Stanley Cohen discovered EGF and was awarded a Noble prize in 1986 for it. As the Noble prize may signify, the molecule is significant and powerful and directly stimulates the proliferation of epidermal cells.
When it comes to Sh-Oligopeptide-1 in a cosmetic product, it has pretty well-established wound healing and skin renewal properties. It might even do more than that. According to a 2012 study on a serum containing barley bioengineered epidermal growth factor, "clinical evaluations showed statistically significant improvement in the appearance of fine lines and rhytids, skin texture, pore size, and various dyschromatic conditions apparent within the first month of use, and continuing improvement trends for the duration of the study" (which was 3 months).
This all sounds amazing, "give me some EGF Serum", we can hear you say! But as we wrote in the intro, the topic is complex and controversial so here are some of the questions that keep coming up around slathering EGF all over our face.
The first and biggest concern is that if EGF is so good at stimulating cell proliferation, how does it relate to cancer? Is the definition of cancer not "cells proliferating out of control"? Most experts agree on this answer: EGF is mitogenic (= stimulates cell proliferation) but not mutagenic (= does not alter the cell to make it cancerous). If you do not have cancer, you will not get cancer from EGF. However, if you have cancerous cells, EGF will help them to spread, just like it helps healthy cells. So if you have a lot of moles, excessive UV exposure in the past, or if you have any of the skin cancer risk factors, we suggest you should think twice about using EGF products. The same is true if you have psoriasis, a skin disease related to the abnormal growth of epidermal skin cells. You do not want to add fuel to the fire with EGF.
Other (less serious) concerns are if EGF can properly penetrate the skin (as it is a medium-sized, polar molecule, so a special delivery system is probably needed), if it can affect collagen synthesis (or just works on the surface plumping up only the upmost layers of the skin) and if it has beneficial effects at all when used in isolation versus when used in a "conditioned media" that contains lots of growth factors resembling the synergistic balance found in the skin.
Overall, our impression is that EGF is definitely a potent molecule. Some EGF products have a cult-like following adding anecdotal evidence to the clinical studies showing EGF has a beneficial effect on the skin. If you like experimenting, by all means, go ahead (unless you have psoriasis or high skin cancer risk factors), but if you are a better safe than sorry type, stick to daily SPF + a good retinoid product. This duo is still the golden standard of anti-aging.
Are you interested in Growth Factors and skincare? We have some more here:
- Human Fibroblast Conditioned Media - a growth factor cocktail used in some cosmetic products
- Insulin-like growth factor 1, aka sh-Oligopeptide -2 - a pal of EGF composed of 70 amino acids
- Vascular Endothelial Growth Factor, aka Sh-Polypeptide-9 - part of a GF cocktail trade named BIO-Placenta
When it comes to grape and skincare, the seed extract and the seed oil steals most of the show. The reason for that is that the seed contains the majority of the skin goodies, the antioxidant superstar polyphenols.
The fruit also contains some, but it's less potent. However - according to manufacturer info - the fruit extract is not only an antioxidant, but it's also a soothing, moisturizing and nourishing agent.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
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| what‑it‑does | solvent |
| what‑it‑does | surfactant/cleansing | emulsifying | perfuming |
| irritancy, com. | 0, 3 |
| what‑it‑does | surfactant/cleansing |
| what‑it‑does | surfactant/cleansing | emulsifying |
| com. | 0 |
| what‑it‑does | solvent | emulsifying | perfuming | surfactant/cleansing |
| irritancy, com. | 0-1, 0-2 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | surfactant/cleansing | emulsifying |
| what‑it‑does | buffering |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 0, 2-3 |
| what‑it‑does | surfactant/cleansing | viscosity controlling |
| what‑it‑does | emollient | emulsifying | viscosity controlling |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | abrasive/scrub |
| what‑it‑does | chelating |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | surfactant/cleansing | emulsifying |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1-2 |
| what‑it‑does | chelating |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | soothing | antioxidant | moisturizer/humectant |
| what‑it‑does | colorant |
| what‑it‑does | perfuming |