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This product has been discontinued. See the current version here.
Defenage 24/7 Barrier Balance Cream

24/7 Barrier Balance Cream (Discontinued)

Intense hydrating cream infused with Age-Repair Defensins®, multi-action barrier balancing ingredients and skin brightening skincare actives work together to regenerate and rejuvenate the appearance of skin. • Innovative formula helps replenish and balance the skin's natural barrier. • Revives radiance and improves overall tone and texture for remarkably smooth, even skin. • With regular use, skin looks brighter and feels firmer.
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Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water (Aqua) solvent
Carthamus Tinctorius (Safflower) Oleosomes emollient goodie
Butyrospermum Parkii (Shea) Butter emollient goodie
Macadamia Integrifolia Seed Oil emollient goodie
Niacinamide cell-communicating ingredient, skin brightening, anti-acne, moisturizer/​humectant superstar
Yeast Extract moisturizer/​humectant goodie
Ammonium Acryloyldimethyltaurate/VP Copolymer viscosity controlling
Helianthus Annuus (Sunflower) Seed Oil emollient 0, 0 goodie
Phospholipids skin-identical ingredient, emollient goodie
Alpha-Defensin 5
Beta-Defensin 3
Hyaluronic Acid skin-identical ingredient, moisturizer/​humectant goodie
Ophiopogon Japonicus Root Extract
Hydrolyzed Candida Saitoana Extract
Sea Whip Extract
Lycium Chinense Fruit Extract antioxidant
Vaccinium Angustifolium Fruit Extract soothing
Vaccinium Marcrocarpon Fruit (Cranberry) Fruit Extract
Rosmarinus Officinalis (Rosemary) Leaf Extract antioxidant, soothing, antimicrobial/​antibacterial goodie
Panthenol soothing, moisturizer/​humectant 0, 0 goodie
Alumina viscosity controlling, abrasive/​scrub
Tocopheryl Acetate antioxidant 0, 0
Ubiquinone antioxidant goodie
Alanyl Glutamine moisturizer/​humectant
Leuconostoc/Radish Root Ferment Filtrate antimicrobial/​antibacterial, preservative
Xanthan Gum viscosity controlling
Phytic Acid chelating
Polysorbate 20 emulsifying, surfactant/​cleansing 0, 0
Caprylic/Capric Triglyceride emollient
Phenoxyethanol preservative
Caprylyl Glycol moisturizer/​humectant, emollient
Ethylhexylglycerin preservative
Hexylene Glycol solvent, emulsifying, perfuming, surfactant/​cleansing 0-1, 0-2
Potassium Sorbate preservative
Sodium Chloride viscosity controlling
Fragrance perfuming icky

Defenage 24/7 Barrier Balance Cream
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Also-called: Safflower Oleosomes | What-it-does: emollient, emulsion stabilising

In general, oleosomes   are tiny-winy (micron sized) spheres that store emollient plant oils (+ some other things). In particular, Safflower Oleosomes are created from safflower seeds and carry safflower seed oil and vitamin E.

According to the manufacturer, oleosomes work both as natural emulsifiers as well as time-released delivery systems. Oleosomes on the skin do not collapse at once, but slowly and they deliver the stored emollient plant oil and vitamin E over an extended period of time giving the skin long-lasting moisture

Also-called: Shea Butter | What-it-does: emollient

Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.

But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat. 

Also-called: Macadamia Oil | What-it-does: emollient

The golden yellow oil coming from the Macadamia nut, a native Australian nut. Similar to other plant oils, it's loaded with emollient and nourishing fatty acids. It's a high oleic acid oil (50-67% oleic acid and only 0-5% linoleic acid) that makes it very emollient and ideal for dry skin types.

Its unique property is that it contains high amounts of a rare fatty acid called palmitoleic acid (12-25%) that give Macadamia oil a "cushiony" feel. It's also easily absorbed and makes the skin soft and supple. 

Niacinamide - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

Yeast Extract - goodie
What-it-does: moisturizer/humectant

You probably know yeast from the kitchen where you put it into milk with a little sugar and then after a couple of minutes brownish bubbles form. That is the fungi fermenting the sugar

As for skin care, yeast contains beta-glucan that is a great soothing ingredient and also a mild antioxidant.  The yeast extract itself is a silky clear liquid that has some great moisturizing, skin protecting and film-forming properties on the skin. 

Also-called: Aristoflex AVC | What-it-does: viscosity controlling

A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky. 

It works over a wide pH range and is used between 0.5-1.2%.

Also-called: Sunflower Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more  we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.

It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.

Phospholipids - goodie

A type of lipid that's the major (about 75%) component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient.

It has a water-loving head with two water-hating tails and this structure gives the molecule emulsifying properties. It is also often used to create liposomes, small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and help its absorption.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

  • It’s naturally in our skin and behaves there like a sponge
  • It can bind up to 1000 times its own weight in water
  • It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
  • High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
  • Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
  • Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
  • Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
Read all the geeky details about Hyaluronic Acid here >>

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: antioxidant

We don't have description for this ingredient yet.

Also-called: Blueberry Extract | What-it-does: soothing

We don't have description for this ingredient yet.

Also-called: Cranberry Fruit Extract;Vaccinium Macrocarpon Fruit Extract | What-it-does: astringent

We don't have description for this ingredient yet.

Also-called: Rosemary Leaf Extract | What-it-does: antioxidant, soothing, antimicrobial/antibacterial

The extract coming from the lovely herb, rosemary. It contains lots of chemicals, including flavonoids, phenolic acids, and diterpenes. Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. 

The leaves contain a small amount of essential oil (1-2%) with fragrant components, so if you are allergic to fragrance, it might be better to avoid it. 

Panthenol - goodie
Also-called: Pro-Vitamin B5 | What-it-does: soothing, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

Also-called: Aluminum Oxide, Al2O3 | What-it-does: viscosity controlling, absorbent/mattifier, abrasive/scrub

A multi-functional helper ingredient that's used mainly as a pigment carrier.  The pigment can be an inorganic sunscreen (such as titanium dioxide) or a colorant that is blended with alumina platelets and then often coated with some kind of silicone (such as triethoxycaprylylsilane). This special treatment enables pigments to be evenly dispersed in the formula and to be spread out easily and evenly upon application. It is super useful both for mineral sunscreens as well as for makeup products. 

Other than that, alumina can also be used as an absorbent (sometimes combined with the mattifying powder called polymethylsilsesquioxane), a viscosity controlling or an opacifying (reduces the transparency of the formula) agent.

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

Ubiquinone - goodie
Also-called: Coenzyme Q10 | What-it-does: antioxidant

Thanks to Nivea, Q10 is a pretty well-known ingredient and the fame and Beiersdorf's (the parent company of Nivea) obsession with it are not for no reason. It's an antioxidant found naturally in human cells where it plays a big role in energy production.

In fact, it's so important for energy production that if taken as an oral supplement it has a caffeine-like effect and if taken at night you will probably not sleep very well (so you should take it in the morning). Q10 supplementation is not a bad idea: it not only gives you energy but research also shows that oral Q10 increases the Q10 level of the skin (of course, it decreases with age like pretty much every good thing in the skin) and may help to reduce wrinkles. If you are not for supplements, dietary sources include fish, spinach, and nuts.

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

Also-called: Fermented Radish Root | What-it-does: antimicrobial/antibacterial, preservative

It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. During the fermentation process, a peptide is secreted from the bacteria that has significant antimicrobial properties

It is one of the more promising natural preservatives that can be used even alone (recommended at 2-4%), but it's not as effective as more common alternatives, like parabens or phenoxyethanol

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

What-it-does: chelating

Though its name says acid, it's not really an exfoliant. It's a plant extract with some antioxidant properties. Its main thing in cosmetic products is to neutralize the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.  It's a natural alternative to sometimes bad-mouthed chelating agents, EDTAs.

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular. 

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

What-it-does: solvent, emulsifying, perfuming, surfactant/cleansing | Irritancy: 0-1 | Comedogenicity: 0-2

Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable. 

Hexylene Glycol is also part a preservative blend named Lexgard® HPO, where it helps the effectiveness of current IT-preservative, phenoxyethanol

What-it-does: preservative

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4). 

But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.

Also-called: Salt | What-it-does: viscosity controlling

Sodium chloride is the fancy name of salt. Normal, everyday table salt

If (similar to us) you are in the weird habit of reading the label on your shower gel while taking a shower, you might have noticed that sodium chloride is almost always on the ingredient list. The reason for this is that salt acts as a fantastic thickener in cleansing formulas created with ionic cleansing agents (aka surfactants) such as Sodium Laureth Sulfate. A couple of percents (typically 1-3%) turns a runny surfactant solution into a nice gel texture.

Fragrance - icky
Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.  

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does emollient
Tiny-winy (micron sized) spheres that store emollient safflower seed oil and vitamin E. Oleosomes are both natural emulsifiers and time-released delivery systems that give the skin long-lasting moisture.  [more]
what‑it‑does emollient
Shea butter that's considered to be a magic moisturizer and emollient. It is also soothing and rich in antioxidants. [more]
what‑it‑does emollient
The golden yellow oil coming from the Macadamia nut, a native Australian nut. Similar to other plant oils, it's loaded with emollient and nourishing fatty acids. [more]
what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
what‑it‑does moisturizer/humectant
A silky clear liquid that has great moisturizing, skin protecting and film-forming properties on the skin. [more]
what‑it‑does viscosity controlling
A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. [more]
what‑it‑does emollient
irritancy, com. 0, 0
Sunflower Oil - it's a great emollient that protects & enhances the skin barrier. [more]
what‑it‑does skin-identical ingredient | emollient
A type of lipid that's the major component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient. It's also often used to create liposomes. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
what‑it‑does antioxidant
what‑it‑does soothing
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Rosemary leaf extract - Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. [more]
what‑it‑does soothing | moisturizer/humectant
irritancy, com. 0, 0
Pro-Vitamin B5 is a goodie that moisturises the skin, has anti-inflammatory, skin protecting and wound healing properties. [more]
what‑it‑does viscosity controlling | abrasive/scrub
A multi-functional helper ingredient that's used mainly as a pigment carrier helping pigments in mineral sunscreens and color cosmetics to flow freely and evenly and not to clump. [more]
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does antioxidant
Q10 - an antioxidant found naturally in human cells where it plays an important role in energy production. As for skincare, it works as an awesome antioxidant that might also be able to reduce wrinkle depth. [more]
what‑it‑does moisturizer/humectant
what‑it‑does antimicrobial/antibacterial | preservative
It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. [more]
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does chelating
Though its name says acid, it's not really an exfoliant. It's a plant extract with some antioxidant properties. Its main thing in cosmetic products is to neutralize the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0, 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does solvent | emulsifying | perfuming | surfactant/cleansing
irritancy, com. 0-1, 0-2
Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.  Hexylene Glycol is also part a preservative blend named Lexgard® [more]
what‑it‑does preservative
A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast. [more]
what‑it‑does viscosity controlling
Sodium chloride is the fancy name of salt. Normal, everyday table salt.  If (similar to us) you are in the weird habit of reading the label on your shower gel while taking a shower, you might have noticed that sodium chloride is almost always on the ingredient list. [more]
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]