Beauty Molecules Molecular Synbiotic Serum Shot
Ingredients overview
Highlights
Key Ingredients
Skim through
Bielenda Beauty Molecules Molecular Synbiotic Serum ShotIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved.
It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula.
A type of sugar that has water-binding properties and helps to keep your skin hydrated.
Ectoin is a surprisingly well-researched, multi-functional active that can do from pollution & light protection to skin hydration, soothing, and barrier repair, several things to your skin.
It is an extremolyte, a small stress-protection molecule that protects microorganisms living under extreme conditions such as salt lakes, hot springs, arctic ice, the deep sea, or deserts. It was discovered in 1985 in a microorganism living in a salt lake in the Egyptian desert.
The key skill of Ectoin is protection that applies also to the skin. Its main mode of action is binding water molecules (aka kosmotropic) and creating hydro complexes. These complexes then surround important biomolecules (e.g. cells, proteins, enzymes) and form a stabilizing hydration shell around them.
This protection mechanism means good things when it comes to our skin: Ectoin has antioxidant, anti-inflammatory, pollution& light protecting, skin hydrating, barrier repairing as well as anti-aging properties.
A placebo-controlled 10-person study examined a four-week treatment with 0.5% Ectoin in the crow's feet area and found a significant anti-wrinkle effect (-19% mean wrinkle depth) in 100% of the participants. Another double-blind, placebo-controlled clinical study with 24 participants used a 2% Ectoin cream twice a day for 4 weeks and found an improvement in all of the measured parameters, such as wrinkle volume, skin scaling, roughness, and elasticity.
Another remarkable property of Ectoin is protecting the epidermal immune cells called Langerhans cells from UV damage. 0.3% and 0.5% Ectoin cream was used twice a day for 14 days on the forearm and then irradiated with 1.5 MED UV (one and a half times the UV dose that causes detectable redness). While the untreated, UV-stressed area showed a 40% decrease in viable Langerhans cells, 0.5% Ectoin showed 100% protection (and 0.3% showed ~95% protection).
The soothing efficacy is also backed up by multiple in-vivo studies. A 20-person study compared 1% Ectoin cream to 0.25% hydrocortisone treatment on surfactant irritated skin and found similar effectiveness in reducing skin redness. Another study with 23 females with sensitive skin found that a 1% Ectoin cream helped to tolerate a 0.5% or 1% retinol treatment much better.
A tiny, 5-person study examined the long-term (7 days) skin hydration effect of 1% Ectoin. During the study, hydration levels increased up to 200% compared to placebo, and even 7 days after stopping the treatment hydration status was largely preserved. Higher concentration (5-7%) Ectoin treatments are also used as OTC medical products for the treatment of eczema or atopic skin.
The anti-pollution magic properties are also well-established and Ectoin is currently the only anti-pollution active ingredient approved for use in medical products (e.g. inhalation solutions) in Europe. Clinical studies showed a reduction of inflammations in human lungs of patients with COPD (a pulmonary disease) and pollution-induced asthma. But coming back to the skin, Ectoin protects both from PMs (Particulate Matters, including ultrafine) as well as PAHs (Polycyclic Aromatic Hydrocarbons) and heavy metals.
If that weren't enough, Ectoin is also shown to protect the skin from blue and visible light, and pigmentation resulting from environmental stress (think UV, pollution, oxidative stress).
All in all, we think Ectoin is one of those under-the-radar actives that deserves more hype than it is currently getting. As an amazing all-around skin protectant, it is a useful addition to any skincare routine.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
A skin protecting ingredient obtained by enzymatic synthesis from natural sugars (sucrose and maltose). It's claimed to be a bio-selective substrate that protects and stimulates the beneficial microbial skin flora without doing the same with pathogens and undesirable flora. It also stimulates the antimicrobial peptide release by keratinocytes (skin cells).
A helper ingredient that usually comes to the formula coupled with PEG-40 Hydrogenated Castor Oil. The two together work as surfactants and oil solubilizers. It's a non-sticky duo that works at low concentration and is often used to solubilize fragrance components into water-based formulas.
Biosaccharide Gum-1 is a pretty interesting kind of sugar ingredient that is created from sorbitol via bacterial fermentation.
According to the manufacturer it’s a “S.M.A.R.T.” sugar: it has Soothing, Moisturizing, Anti-aging, Restructuring and Touch properties. Let’s look at them quickly one by one.
Soothing: the manufacturer tested out the soothing effect in vivo (meaning on humans that is always a good thing!) by measuring how 3% Biosaccharide Gum-1 decreased the tingling sensation caused by 10% lactic acid. The result was good: the tingling was decreased by 47%.
Moisturizing: Compared to famous hyaluronic acid, it turns out that the two are great together. HA has a quicker effect and provides more instant hydration (much more hydration was measured after 1h of application), while our nice sugar has a somewhat delayed effect demonstrating stronger hydration after 3h of application. After 8 hours both had similar moisturizing effect.
Anti-aging: According to ex-vivo tests (meaning not on humans, so do not trust it too much) Biosaccharide Gum-1 can stimulate a protein in our skin called sirtuin-1. This is supposed to help our skin cells to live longer, and function better.
Resurfacing: The sirtuin-1 stimulation also results in quicker cell renewal - something that happens anyway but slows down as we age. And the quicker cell renewal is good because it helps the regeneration of the barrier function. That is especially nice for fragile, sensitive skin.
Touch: our fermented sugar is not only good to the skin, but it also feels great on the skin. It gives a nice “soft touch” feeling and makes the products pleasant to use.
The bottom line is that the above info is from the manufacturer (and we could not find any relevant independent research) so obviously take it with a grain of salt. But Biosaccharide Gum-1 does look as an interesting and promising ingredient that’s why it earned our goodie rating.
- It’s a polyhydroxy acid (PHA), that is often referred to as next generation AHA
- It gently lifts off dead skin cells form the skin surface making skin smooth and even
- In the long term it provides anti-aging benefits, like increased skin thickness and decreased wrinkles (though a tad less than even more proven superstar AHAs)
- It’s a great moisturizer and even helps to repair impaired skin barrier
- It’s antioxidant, and does not make your skin more sensitive to the sun
- It can be used even if your skin is very sensitive, rosacea prone or if you are post cosmetic procedure
We don't have description for this ingredient yet.
Centella Asiatica - or sometimes also called Gotu Kola or Cica - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.
Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).
One of the biological activities of the centellosides is to be able to stimulate GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells), and especially hyaluronic acid synthesis in our skin. This is probably one of the reasons why Centella Asiatica Extract has nice skin moisturizing properties that was confirmed by a 25 people, four weeks study along with Centella's anti-inflammatory effects.
Madecassoside can also help in burn wound healing through increasing antioxidant activity and enhancing collagen synthesis. Asiaticoside was shown to increase antioxidant levels on rats skin when applied at 0.2%.
Centella Asiatica also often shows up in products that try to treat cellulite or striae. Of course, it cannot make a miracle but it might have some effect via regulating microcirculation and normalizing the metabolism in the cells of connective tissues.
Bottom line: Gotu Kola is a great plant ingredient with proven wound healing, anti-inflammatory, and antioxidant properties. Nice to spot on any ingredient list.
It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding).
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
A non-essential amino acid (meaning that our body can produce it) that's also one of the major building blocks of collagen. According to the Futurederm blog, it might be able to improve wrinkles when combined with other amino acids, glycine and leucine
We don't have description for this ingredient yet.
A type of sugar molecule, that has water-binding properties and helps to keep your skin hydrated.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
We don't have description for this ingredient yet.
A mildly viscous, amber-colored liquid with fatty odor, made from Castor Oil and polyethylene glycol (PEG).
If it were a person, we’d say, it’s agile, diligent & multifunctional. It’s mostly used as an emulsifier and surfactant but most often it is used to solubilize fragrances into water-based formulas.
A nice little helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. It's derived from cellulose, the major component of the cell wall of green plants. It is compatible with most co-ingredients and gives a very good slip to the formulas.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
It's a very alkaline stuff that helps to set the pH of the cosmetic formula to be just right. It's similar to the more often used sodium hydroxide and pretty much the same of what we wrote there applies here too.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
A handy helper ingredient (a polymer, i.e. big molecule from repeated subunits) that is used to stabilize emulsions as well as to thicken up products. It can also stabilize foam in cleansing products.
Officially, CosIng (the official EU ingredient database) lists Aluminum Hydroxide 's functions as opacifying (making the product white and non-transparent), as well as emollient and skin protectant.
However, with a little bit of digging, it turns out Aluminum Hyroxide often moonlights as a protective coating for UV filter superstar Titanium Dioxide. Specifically, it protects our skin from the harmful effects of nasty Reactive Oxygen Species (free radicals derived from oxygen such as Superoxide and Hydrogen Peroxide) generated when Titanium Dioxide is exposed to UV light. Btw, chlorine in swimming pool water depletes this protective coating, so one more reason to reapply your sunscreen after a dip in the pool on holiday.
Other than that, Aluminum Hydroxide also often shows up in composite pigment technologies where it is used the other way around (as the base material and not as the coating material) and helps to achieve higher color coverage with less pigment.
Cellulose is an important component of the cell walls of green plants and it's the most abundant natural polymer (big molecule from repeated subunits) on Earth. If the polymer structure is not too big (less than 200 repeated units), cellulose becomes microcrystalline cellulose.
In skin care, it comes as a fine or less fine white powder. The less fine (bigger particle size) version is used as a gentle scrubbing agent (a nice natural, biodegradable alternative to now banned plastic polyethylene) and the ultra fine version is used as a helper ingredient that gives a super-silky, soft touch, reduces tackiness or greasiness and can also be used as a mattifying agent.
Combined with Cellulose Gum, it also works as a nice gelling agent.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.
No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.
In high amounts, it can be a skin irritant, but don’t worry, it’s never used in high amounts.
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
An inorganic (as in no carbon in its molecule, it is Cr2O3X(OH), the hydrated version of this guy) pigment that gives blue-green shades. It is not permitted in lip products in the US.
Yellow Iron Oxide is the super common inorganic (as in no carbon atom in the molecule) pigment that gives the yellow tones in your foundation. Blended with red and black iron oxides, it is essential in all "flesh-toned" makeup products.
Chemically speaking, it is hydrated iron III oxide and depending on the conditions of manufacture, it can range from a light lemon to an orange-yellow shade.
We don't have description for this ingredient yet.
You may also want to take a look at...
| what‑it‑does | solvent |
| what‑it‑does | solvent | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | antioxidant | soothing | moisturizer/humectant |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | exfoliant | chelating |
| what‑it‑does | soothing | antioxidant | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | preservative |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | buffering |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | buffering |
| what‑it‑does | surfactant/cleansing | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | buffering |
| what‑it‑does | buffering |
| what‑it‑does | emollient | moisturizer/humectant | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | preservative |
| what‑it‑does | preservative | perfuming | solvent | viscosity controlling |
| what‑it‑does | preservative |
| what‑it‑does | perfuming |
| what‑it‑does | colorant |
| what‑it‑does | colorant |
| irritancy, com. | 0, 0 |
| what‑it‑does | colorant |
| irritancy, com. | 0, 3 |