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Apidermin Expert SerumIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A light emollient ester (C8-10 fatty acids connected to C12-18 fatty alcohols) that absorbs quickly and leaves a dry but silky finish on the skin. In terms of skin feel, it is similar to Dicaprylyl Carbonate, another commonly used light emollient.
A clear, almost colorless (or slightly yellowish) oily liquid (an ester to be precise) that's used as a medium spreading emollient. It gives skin a nice and smooth after-feel and it's very good at reducing oiliness or greasiness coming from other heavier oils in the formula.
When it comes to cosmetic oils and hype, argan oil is for sure leading the way. Dubbed as the "liquid gold of Morocco", we have to admit we have some trouble determining why this oil enjoys such a special miracle status. Not that it's not good, it is good, even great but reading the research about argan and a bunch of other plant oils we just do not see the big, unique differentiating factor (though that might be our fault not reading enough, obvs.)
So, argan oil comes from the kernel of the argan fruit that comes from the argan tree that grows only in Morocco. The tree is slow growing and getting the oil is a hard job. The traditional process is that the ripe argan fruits fall from the tree, then goats eat them up and poop out the seeds. The seeds are collected and smashed with a stone to get the kernels inside. This part is the hard one as the seeds have extremely hard shells. Once the kernels are obtained, the oil is pressed out from them (the kernels contain about 50% oil).
As for skincare, argan oil is loaded with lots of skin goodies (but so are many other plant oils): it contains 80% nourishing and moisturizing unsaturated fatty acids, mainly oleic (38-50%), linoleic (28-38%) and palmitic (10-18%). It also contains a relatively large amount of antioxidant vitamin E (600-900 mg/kg, about twice as much as olive), small amounts of antioxidant phenols (including caffeic acid, ferulic acid, and epicatechin), as well as some rare sterols with soothing and anti-inflammatory properties.
Thanks to all the above goodness in argan oil, it can greatly nourish and moisturize the skin and hair. It's also claimed to be able to neutralize collagen-damaging free radicals, help reduce scars, and revitalize and improve skin elasticity. You can even read that argan might help acne-prone skin, but being a high oleic oil, we would be careful with that.
All in all, argan oil is a real goodie but we do not fully understand the special miracle status it enjoys.
We don't have description for this ingredient yet.
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>
A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky.
It works over a wide pH range and is used between 0.5-1.2%.
A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A handy helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right.
For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.
BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.
Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.
It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the king being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince George, two steps away from the throne. Retinyl palmitate will be then Prince Charlotte (George's little sister), quite far (3 steps) away from the throne.
By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:
retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid
As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective.
What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD, director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre.
Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here. It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA.
We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!
Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.
- Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
- It has to be converted in the skin to retinoic acid to work its magic
- Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
- A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
- It makes skin less wrinkled, smoother, firmer and tighter
- It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
- Possible side effects and irritation are also much less than with retinoic acid
- Do not use whilst pregnant
Thanks to Nivea, Q10 is a pretty well-known ingredient and the fame and Beiersdorf's (the parent company of Nivea) obsession with it are not for no reason. It's an antioxidant found naturally in human cells where it plays a big role in energy production.
In fact, it's so important for energy production that if taken as an oral supplement it has a caffeine-like effect and if taken at night you will probably not sleep very well (so you should take it in the morning). Q10 supplementation is not a bad idea: it not only gives you energy but research also shows that oral Q10 increases the Q10 level of the skin (of course, it decreases with age like pretty much every good thing in the skin) and may help to reduce wrinkles. If you are not for supplements, dietary sources include fish, spinach, and nuts.
As for skincare, Q10 comes in the form of a yellow, oil-soluble powder that's shown to absorb into the upper layer of the skin and act there like an awesome antioxidant. It not only has preventative effects but might also be able to reduce the depth of wrinkles, though 0.3% Q10 was used in the study that counts as really high (products containing that much should be very yellow!).
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
It's a "bioengineered" from of skin building block N-acetylglucosamine-6-phosphate (NAG6P) that is used by the skin to synthesize important skin-identical humectants like GAGs and hyaluronan.
According to the manufacturer's in-vitro and ex-vivo (made in the lab not on real people) tests, NovHyal can boost GAGs production both in the upper and middle layer of the skin by 84% in 10 days. It can also increase hyaluronic acid synthesis by 282% in just 2 days. Sounds good, though some in-vivo tests (made on real people) would be nice.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
A helper ingredient that is used as a bulking and viscosity controlling agent. It is also an emulsion stabilizer in water-in-oil emulsions, where water droplets are dispersed in the continuous oil phase and not the other way round.
It can also be used as a heat generating agent in water-less formulas as it has an instant heat-generating chemical reaction with water.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
We don't have description for this ingredient yet.
A chemically chopped up version of wheat protein that consists mainly of amino acids (the building blocks), peptides (a couple of amino acids together), and proteins (lots of amino acids together).
It has moisturizing and film-forming properties and might be able to counteract the irritating effects of cleansing agents in cleansers and shampoos. It can also condition and repair damaged hair leaving it soft, silky and smooth.
We don't have description for this ingredient yet.
A non-essential amino acid (meaning that our body can produce it) that's also one of the major building blocks of collagen. According to the Futurederm blog, it might be able to improve wrinkles when combined with other amino acids, glycine and leucine
Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.
In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can do for the skin.
A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing.
Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former. Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs.
A fancy name for sugar. Luckily when you put it on your skin it's good for you not like when you eat it. :) It has water-binding properties, which means that it helps to keep your skin nice and hydrated.
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
A natural polysaccharide (big sugar molecule) coming from red edible seaweeds. It is used as a helper ingredient for its gelling, thickening and stabilizing properties.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
It's a pretty new anti-aging ingredient that is a "safe and pre-activated source of energy to feed aging skin cells".
It's part of an anti-aging complex trade named Neodermyl, where methylglucoside phosphate is combined with the essential amino acids proline, lysine and also copper. This complex is claimed to be able to increase the collagen I and III production of skin and even more surprisingly, also the elastin production. Both slow down with age and beeing able to boost the skin's own production of these super important proteins results in improved skin firmness and elasticity.
This is a very big deal, especially the elastin part, as there is not yet a clinically proven active ingredient that is able to boost the skin's own elastin production. There are also very few ones (think vitamin C, glycolic acid, and retinol) that are proven to boost collagen. The claims about Neodermyl are not yet confirmed in independent studies but the manufacturer did do some very convincing testing that showed a visible reduction of wrinkle depth and volume in just 15 days. If you are into anti-aging, this is a new active that might be worth a try.
An essential amino acid - mineral complex that is part of the pretty new anti-aging complex called Neodermyl. The manufacturer claims that the complex is able to boost skin's own collagen I and III as well as elastin production. Read more details at methylglucoside phosphate.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
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what‑it‑does | solvent |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | emollient |
what‑it‑does | emollient |
what‑it‑does | antioxidant | emollient |
what‑it‑does | emollient |
what‑it‑does | skin-identical ingredient | emollient |
irritancy, com. | 0, 1 |
what‑it‑does | viscosity controlling |
what‑it‑does | solvent |
what‑it‑does | moisturizer/humectant | emollient |
what‑it‑does | chelating |
what‑it‑does | buffering |
what‑it‑does | cell-communicating ingredient |
irritancy, com. | 1-3, 1-3 |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | antioxidant |
what‑it‑does | preservative |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | moisturizer/humectant |
what‑it‑does | moisturizer/humectant |
what‑it‑does | viscosity controlling |
what‑it‑does | viscosity controlling |
what‑it‑does | moisturizer/humectant |
what‑it‑does | moisturizer/humectant |
what‑it‑does | viscosity controlling |
what‑it‑does | skin-identical ingredient |
what‑it‑does | skin-identical ingredient |
what‑it‑does | skin-identical ingredient |
what‑it‑does | moisturizer/humectant |
what‑it‑does | moisturizer/humectant | solvent |
irritancy, com. | 0, 1 |
what‑it‑does | viscosity controlling |
what‑it‑does | preservative |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | perfuming |