The Inkey List Caffeine Serum
The Inkey List

Caffeine Serum

THE INKEY LIST’s Caffeine Serum harnesses the anti-inflammatory, antioxidant powers of coffee to bring them to your skin.
Uploaded by: make_and_up on 27/09/2018

Ingredients overview

Propanediol
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
,
Polyglyceryl-6 Distearate
what‑it‑does emulsifying
,
Cetyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling
irritancy, com. 2 2
A fatty (the good, non-drying kind of) alcohol that makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier).
,
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
what‑it‑does viscosity controlling
A helper ingredient that's good at stabilizing water-based formulas and also serves as a thickener. It's especially recommended for low pH products, like exfoliants.
,
Jojoba Esters
what‑it‑does soothing | emollient | moisturizer/humectant
Jojoba-derived emollient wax esters (fatty acid + fatty alcohol) that make your skin feel nice and smooth. [more]
,
Glyceryl Dibehenate
what‑it‑does emollient
The combination of glycerin + two behenic acid molecules that works as an oil-gelling agent, emulsion stabilizer, and high-performance compacting agent in pressed powders.
,
Albizia Julibrissin Bark Extract, Squalane
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
,
Caffeine
what‑it‑does antioxidant
The well-known stimulant from coffee. It has nice antioxidant properties and can improve the microcirculation. Might be helpful for dark circles, puffy eyes, as well as cellulite and hair loss. [more]
, [more]
Polyglyceryl-3 Beeswax
what‑it‑does emulsifying
,
Phospholipids
what‑it‑does skin-identical ingredient | emollient
A type of lipid that's the major component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient. It's also often used to create liposomes. [more]
,
Tribehenin
what‑it‑does emollient
thickening/gelling agent, as a compacting agent for pressed powders (ATO grade), and improves heat stability of emulsions.
,
Ethylhexylglycerin
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
,
Xanthan Gum
what‑it‑does viscosity controlling | emulsifying | surfactant/cleansing
A super commonly used thickener and emulsion stabilizer. [more]
,
Glycine Soja (Soybean) Extract, Polysorbate 60
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
,
Disodium Edta
what‑it‑does chelating | viscosity controlling
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
,
Glyceryl Behenate
what‑it‑does emollient | emulsifying
The combination of glycerin + behenic acid that works as an oil-gelling, emulsion stabilizing or compacting (in pressed powders) agent. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Glycine Soja Sterols
what‑it‑does emollient
,
Leuconostoc/Radish Root Ferment Filtrate
what‑it‑does antimicrobial/antibacterial | preservative
It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. [more]
,
Hyaluronic Acid
what‑it‑does skin-identical ingredient | antioxidant | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
,
Carbomer
what‑it‑does viscosity controlling
It’s a handy white powder that magically converts a liquid into a nice gel formula. [more]
,
Darutoside, Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
,
Palmitoyl Tetrapeptide-7
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
,
Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
[less]

Highlights

Key Ingredients

Antioxidant: Caffeine
what‑it‑does antioxidant
The well-known stimulant from coffee. It has nice antioxidant properties and can improve the microcirculation. Might be helpful for dark circles, puffy eyes, as well as cellulite and hair loss. [more]
,
Hyaluronic Acid
what‑it‑does skin-identical ingredient | antioxidant | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
Cell-communicating ingredient: Palmitoyl Tetrapeptide-7
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
,
Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
Skin-identical ingredient: Squalane
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
,
Phospholipids
what‑it‑does skin-identical ingredient | emollient
A type of lipid that's the major component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient. It's also often used to create liposomes. [more]
,
Hyaluronic Acid
what‑it‑does skin-identical ingredient | antioxidant | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
Soothing: Jojoba Esters
what‑it‑does soothing | emollient | moisturizer/humectant
Jojoba-derived emollient wax esters (fatty acid + fatty alcohol) that make your skin feel nice and smooth. [more]

Show all ingredients by function

Other Ingredients

Antimicrobial/antibacterial: Leuconostoc/Radish Root Ferment Filtrate
what‑it‑does antimicrobial/antibacterial | preservative
It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. [more]
Chelating: Disodium Edta
what‑it‑does chelating | viscosity controlling
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
Emollient: Cetyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling
irritancy, com. 2 2
A fatty (the good, non-drying kind of) alcohol that makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier).
,
Jojoba Esters
what‑it‑does soothing | emollient | moisturizer/humectant
Jojoba-derived emollient wax esters (fatty acid + fatty alcohol) that make your skin feel nice and smooth. [more]
,
Glyceryl Dibehenate
what‑it‑does emollient
The combination of glycerin + two behenic acid molecules that works as an oil-gelling agent, emulsion stabilizer, and high-performance compacting agent in pressed powders.
,
Squalane
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
,
Phospholipids
what‑it‑does skin-identical ingredient | emollient
A type of lipid that's the major component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient. It's also often used to create liposomes. [more]
,
Tribehenin
what‑it‑does emollient
thickening/gelling agent, as a compacting agent for pressed powders (ATO grade), and improves heat stability of emulsions.
,
Glyceryl Behenate
what‑it‑does emollient | emulsifying
The combination of glycerin + behenic acid that works as an oil-gelling, emulsion stabilizing or compacting (in pressed powders) agent. [more]
,
Glycine Soja Sterols
what‑it‑does emollient
Emulsifying: Polyglyceryl-6 Distearate
what‑it‑does emulsifying
,
Cetyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling
irritancy, com. 2 2
A fatty (the good, non-drying kind of) alcohol that makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier).
,
Polyglyceryl-3 Beeswax
what‑it‑does emulsifying
,
Xanthan Gum
what‑it‑does viscosity controlling | emulsifying | surfactant/cleansing
A super commonly used thickener and emulsion stabilizer. [more]
,
Polysorbate 60
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
,
Glyceryl Behenate
what‑it‑does emollient | emulsifying
The combination of glycerin + behenic acid that works as an oil-gelling, emulsion stabilizing or compacting (in pressed powders) agent. [more]
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
Moisturizer/humectant: Propanediol
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
,
Jojoba Esters
what‑it‑does soothing | emollient | moisturizer/humectant
Jojoba-derived emollient wax esters (fatty acid + fatty alcohol) that make your skin feel nice and smooth. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Hyaluronic Acid
what‑it‑does skin-identical ingredient | antioxidant | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
Preservative: Ethylhexylglycerin
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
,
Leuconostoc/Radish Root Ferment Filtrate
what‑it‑does antimicrobial/antibacterial | preservative
It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. [more]
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
Solvent: Propanediol
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
Surfactant/cleansing: Xanthan Gum
what‑it‑does viscosity controlling | emulsifying | surfactant/cleansing
A super commonly used thickener and emulsion stabilizer. [more]
,
Polysorbate 60
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
Viscosity controlling: Cetyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling
irritancy, com. 2 2
A fatty (the good, non-drying kind of) alcohol that makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier).
,
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
what‑it‑does viscosity controlling
A helper ingredient that's good at stabilizing water-based formulas and also serves as a thickener. It's especially recommended for low pH products, like exfoliants.
,
Xanthan Gum
what‑it‑does viscosity controlling | emulsifying | surfactant/cleansing
A super commonly used thickener and emulsion stabilizer. [more]
,
Disodium Edta
what‑it‑does chelating | viscosity controlling
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
,
Carbomer
what‑it‑does viscosity controlling
It’s a handy white powder that magically converts a liquid into a nice gel formula. [more]

Ingredients explained

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

What-it-does: emulsifying

We don't have description for this ingredient yet.

What-it-does: emollient, emulsifying, viscosity controlling | Irritancy: 2 | Comedogenicity: 2

A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). Can be derived from coconut or palm kernel oil.

This horribly long named thing is a helper ingredient that's good at stabilizing water-based formulas and also serves as a thickener. It's especially recommended for low pH products, like exfoliants.

Jojoba-derived emollient wax esters (fatty acid + fatty alcohol) that make your skin feel nice and smooth. Chemically speaking, pure jojoba oil is also a wax ester (read our shiny explanation here), however, the ingredients called jojoba esters on the ingredient lists are made from jojoba oil and/or hydrogenated jojoba oil via interesterification. 

They have multiple versions with variable fatty acid chain length and the ingredient can have a liquid, a creamy, a soft or firm paste, or even a hard wax consistency. The common thing between all versions is, that unlike most normal triglyceride oils, jojoba esters have superior stability, provide non-greasy emolliency and are readily absorbed into the skin

What-it-does: emollient

The combination of glycerin + two behenic acid molecules that works as an oil-gelling agent, emulsion stabilizer, and high-performance compacting agent in pressed powders. We wrote a bit more at its little sis, glyceryl behenate.

Also-called: Persian Silk Tree Bark Extract, Part of Beautifeye

We don't have description for this ingredient yet.

Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

Expand to read more

Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.

The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >> 

Caffeine - goodie
What-it-does: antioxidant

Hello, our favorite molecule that helps us wake up in the morning and then keeps us going through the day. As a super well-known stimulant from coffee, tea and plenty of other soft drinks, Caffeine needs no introduction. So we will skip right to the part where we talk about what the hell it does in so-so many cosmetic products.

Looking at the research, we were surprised to find how versatile Caffeine is. It is a small, water-loving molecule with pretty good skin penetration abilties. Once in the skin, it has nice antioxidant properties, meaning that it reduces the formation of evil free radicals and it might even be useful in preventing UV-induced skin cancers. 

Expand to read more

A well-known thing about Caffeine is that it improves the microcirculation of the blood vessels. Though conventional wisdom and anecdotal evidence says that this property is helpful for dark under-eye circles and puffy eyes, we have to mention that the double-blind research we have found about a 3% caffeine gel concluded that "the overall efficacy of the selected caffeine gel in reducing puffy eyes was not significantly different from that of its gel base."  But you know, the proof is in the pudding.

Another thing Caffeine is used for in body care products is its anti-cellulite effects. In theory, it can speed up the lipolysis process (the "fat burning"  by our cells) and stimulate the draining lymph system that might lead to the improvement of cellulite. But here again, the evidence that it actually makes a measurable, let alone visible,  improvement on actual human beings is limited (we could find only some animal skin studies or caffeine being combined with other actives). 

Last, but not least, we have to write about caffeine and hair growth. The theory is that it can inhibit the activity of the 5-α-reductase enzyme that plays an important role in hair loss and allows a renewed growth phase of the hair. We have found some recent and promising research to back this up. A 2017 study compared a 0.2% caffeine liquid with a 5% Minoxidil  (an FDA approved active to treat baldness) solution and found that  "a caffeine-based topical liquid should be considered as not inferior to minoxidil 5% solution in men with androgenetic alopecia", or English translation means that the caffeine liquid was pretty much as good as the FDA-approved Minoxidil stuff. Not bad!

Overall, we think that caffeine is a very versatile and biologically active ingredient. Even though some of its effects are more hyped up than backed up, it is still a nice to have on many ingredient lists. 

What-it-does: emulsifying

We don't have description for this ingredient yet.

Phospholipids - goodie

A type of lipid that's the major (about 75%) component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient.

It has a water-loving head with two water-hating tails and this structure gives the molecule emulsifying properties. It is also often used to create liposomes, small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and help its absorption.

What-it-does: emollient

It's the triglyceride of behenic acid that works as a thickening or gelling agent, as a compacting agent for pressed powders, and improves heat stability of emulsions. 

What-it-does: preservative

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little of xanthan gum will help make it more gel-like.  Used alone, it can make the formula sticky so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules called glucose and sucrose. It’s approved by Ecocert and also used in the food industry (E415). 

We don't have description for this ingredient yet.

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

What-it-does: emollient, emulsifying

The combination of glycerin + behenic acid that comes either in a fine powder or waxy solid form. Together with the di- and triglyceride of behenic acid, the trio has remarkable gelling properties helping cosmetic chemists to create ultra-soft and non-tacky waterfree gels. They also have great emulsion stabilizing properties, and work as high-performance compacting agents for makeup products that come in the form of pressed powders.

It's also vegetable origin, and Ecocert certified.

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

Expand to read more

It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

Also-called: Soybean Sterols | What-it-does: emollient

We don't have description for this ingredient yet.

Also-called: Fermented Radish Root | What-it-does: antimicrobial/antibacterial, preservative

It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. During the fermentation process, a peptide is secreted from the bacteria that has significant antimicrobial properties

It is one of the more promising natural preservatives that can be used even alone (recommended at 2-4%), but it's not as effective as more common alternatives, like parabens or phenoxyethanol

Hyaluronic Acid - goodie
  • It’s naturally in our skin and behaves there like a sponge
  • It can bind up to 1000 times its own weight in water
  • It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist
  • High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
  • Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
  • Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
  • Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
Read all the geeky details about Hyaluronic Acid here >>

What-it-does: viscosity controlling

It’s a handy white powder that magically converts a product into a nice gel formula. If you see gel in the name of a moisturiser type thing, chances are carbomer will be in the ingredient list. 

It’s not too common, but sometimes there is also a number after it. The reason for it is that carbomer in itself actually refers to a group of stuff and the number shows the weight and type of the molecule. 

We don't have description for this ingredient yet.

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinteleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

Expand to read more

It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

Expand to read more

The GHK part is the important one as it's a type I collagen fragment. When collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more.

Therefore, Palmitoyl Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. 

In Matrixyl 3000, Palmitoyl Tripeptide-1 is coupled with Palmitoyl Tetrapeptide-7  and the duo works in synergy to reduce wrinkles and give younger looking skin. According to the manufacturer's in-vivo (made on real people) test, applying 3% Matrixyl 3000 twice a day for 2 months resulted in all of the following things:

  • 39.4% reduction in surface occupied by deep wrinkles
  • 32.9% reduction in main wrinkle density
  • 19.9% reduction in main wrinkle average depth
  • 16% improvement in roughness
  • 16.2% in lifting effect
  • 5.5% improvement in elasticity
  • 15.5% improvement in skin tone

Manufacturer results, of course, always have to be taken with a pinch of salt, but if you like peptides, the Matryxil 3000 duo is one of the best-proven and most well-known ones and it's something that is worth trying.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

Expand to read more

Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

You may also want to take a look at...