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SkinMedica Ha5 Rejuvenating Hydrator

Ha5 Rejuvenating Hydrator

Provides immediate smoothing in the appearance of fine lines and wrinkles, and supports the skin's natural ability to replenish its own hyaluronic acid for overall skin health. Appropriate for all skin types
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Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water/Aqua solvent
Dimethicone emollient 0, 1
Hdi/Trimethylol Hexyllactone Crosspolymer
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Bis-PEG-8 Dimethicone surfactant/​cleansing
Polysilicone-11
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer viscosity controlling
Sodium Hyaluronate Crosspolymer skin-identical ingredient, antioxidant, moisturizer/​humectant goodie
Hydrolyzed Hyaluronic Acid moisturizer/​humectant goodie
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Vitis Vinifera (Grape) Flower Cell Extract
Vibrio Alginolyticus Ferment Filtrate abrasive/​scrub
Alteromonas Ferment Extract soothing goodie
Porphyridium Cruentum Extract
Whey Protein cell-communicating ingredient goodie
Plankton Extract
Trehalose moisturizer/​humectant goodie
Urea skin-identical ingredient, moisturizer/​humectant goodie
Serine skin-identical ingredient goodie
Algin viscosity controlling 4, 4
Caprylyl Glycol moisturizer/​humectant, emollient
Pullulan
Disodium Phosphate buffering
Potassium Phosphate buffering
Pentylene Glycol solvent, moisturizer/​humectant
Polymethylsilsesquioxane
Glyceryl Polyacrylate
Sodium Citrate chelating, buffering
Sea Water moisturizer/​humectant, solvent
Sucrose Palmitate emollient, emulsifying, surfactant/​cleansing
Tocopheryl Acetate antioxidant 0, 0
Hydroxyacetophenone antioxidant
Polysorbate 60 emulsifying, surfactant/​cleansing
Propanediol solvent, moisturizer/​humectant
Potassium Sorbate preservative
Citric Acid buffering
Isohexadecane emollient, solvent
Polysorbate 80 emulsifying, surfactant/​cleansing 0, 0
Silica viscosity controlling
Decyl Glucoside surfactant/​cleansing
Tromethamine buffering
Ethylhexylglycerin preservative
Phenoxyethanol preservative
Disodium EDTA chelating

SkinMedica Ha5 Rejuvenating Hydrator
Ingredients explained

Also-called: Aqua;Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

A handy spherical powder that's often combined with fellow spherical powder, Polymethylsilsesquioxane to form a high-performing texturizing duo. The duo is claimed to provide excellent slip, fluidity and overall skin feel and gives soft focus and wrinkle correction to the formula. It also has strong de-tackifying and anti-caking properties. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

What-it-does: surfactant/cleansing

We don't have description for this ingredient yet.

A type of silicone elastomer (rubber-like material with both viscosity and elasticity) whose major function is forming a nice film on the skin.

It is also cosmetically very elegant with a non-tacky, non-oily and smooth skin feel. It also works as a stable delivery system of active materials, has sebum absorption and control properties and upon application, it transforms into a matte appearance with a powdery after feel.

A copolymer is a big molecule that consists not of one but of two repeating subunits. This particular copolymer is a handy helper ingredient to form nice gel textures.

It usually comes to the formula combined with emollients (such as  C13-14 Isoparaffin, Isohexadecane, Isononyl Isononanoate or Squalane) and can be used as an emulsifier and/or thickener to produce milky gel emulsions with a soft and non-tacky skin feel. 

It's a special "cross-linked" from of IT-moisturizer, hyaluronic acid (HA). Cross-linked means that "normal" HA pieces (1-2 million Da molecular weight) are chemically bound togeather to create a big, "infinite" mesh.

The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. This water filled crosslinked HA gel forms a smooth film on the skin and continuously delivers the bound water, so it gives long-term moisturizing benefits.

What-it-does: moisturizer/humectant

Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to retain water, making it plump and elastic. As HA is a polymer, the subunits can be repeated many times (as a high-molecular-weight version), or just a few times (as a low-molecular-weight version).

We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. Hydrolyzed Hyaluronic Acid can also come in different molecular-weight versions with different properties:

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

We don't have description for this ingredient yet.

What-it-does: abrasive/scrub

We don't have description for this ingredient yet.

What-it-does: soothing

A so-called exopolysaccharide (high-molecular-weight polymers) secreted by a microorganism living in hydrothermal deep vents. The manufacturer claims that it soothes and reduces irritation to sensitive skin against chemical (such as drying acne treatments or strong chemical exfoliants), mechanical (such as micro-cuts after shaving) and UVB aggressors.

We don't have description for this ingredient yet.

Whey Protein - goodie
Also-called: Milk Peptide Complex | What-it-does: cell-communicating ingredient

Protein fragments, aka peptides and growth factors derived from milk (whey). It is claimed to boost the production of important extracellular matrix components (the gooey stuff between the skin cells) such as hyaluronic acid, collagen I and fibronectin. The in-vivo (made on people) tests showed reduced wrinkles and improved firmness within two weeks by using 0.5% of Whey Protein.

We don't have description for this ingredient yet.

Trehalose - goodie
What-it-does: moisturizer/humectant

A type of sugar that has water-binding properties and helps to keep your skin hydrated

Urea - goodie
Also-called: Carbamide | What-it-does: skin-identical ingredient, moisturizer/humectant

Yes, it's the thing that can be found naturally in pee. And in the skin. It is an awesome natural moisturizing factor, aka NMF.  NMFs are important components that help the skin to hold onto water and keep it plump, elastic and hydrated. Urea makes up about 7% of NMFs next to other things such as amino acids (40%), PCA (12%) or Lactate (12%).

What makes urea special, is that it is not only a simple moisturizer, but it is thought to be a "small-molecule regulator of epidermal structure and function" meaning that it has a bunch of extra biological activities. It acts as a mild keratolytic agent (some of its moisturizing action is thought to come from urea's ability to break down bonds in the protein called filaggrin and thus freeing up amino acids in the skin), enhances antimicrobial peptide expression and improves skin barrier function

Serine - goodie

Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.

In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can do for the skin.

Also-called: Sodium Alginate | What-it-does: viscosity controlling | Irritancy: 4 | Comedogenicity: 4

A large sugar molecule (aka polysaccharide) that's used as a gelling agent and comes from brown seaweed. 

Combined with calcium salts, it forms a rigid gel used in "rubber masks". 

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

If you ever wondered what those little Listerine breath strips were made of, you found your answer! Pullulan is a polysaccharide polymer, which basically means that it’s a big molecule made up of smaller sugar molecule units.

It dissolves in water and can make a thin, elastic, and moisture-absorbing film when spread on the skin that can cause an instant tightening effect. It can also be used as a thickener to get a silicone-like feel and can be used in peel-off masks. Btw, it's made from fungus via fermentation. 

What-it-does: buffering

We don't have description for this ingredient yet.

What-it-does: buffering

It’s a little helper ingredient that helps to set the pH of a cosmetic formulation to be just right.

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

spherical texturizing powder that's used as a texture enhancer and soft focus agent. It's claimed to give silicone type softness to the formula and also works as a (temporary) wrinkle filler. 

We don't have description for this ingredient yet.

What-it-does: chelating, buffering

A little helper ingredient that is used to adjust the pH of the product. It also helps to keep products stay nice longer by neutralizing the metal ions in the formula (they usually come from water). 

Also-called: Maris Aqua | What-it-does: moisturizer/humectant, solvent

We don't have description for this ingredient yet.

A sugar ester (sucrose + palmitic acid) that works as a natural emulsifier (helps oil and water to mix). According to the manufacturer, it has a great skin-feel, improves smoothness, emolliency and even hydrates the skin.

Combined with another sugar ester, sucrose stearate, it can improve high temperature stability of Sucragel based oily gel cleansers.

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

What-it-does: antioxidant

A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

What-it-does: preservative

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4). 

But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.

What-it-does: buffering

Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA. 

So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh. 

What-it-does: emollient, solvent

A light, velvety, unique skin feel liquid that is a good solvent and also makes the skin feel nice and smooth (aka emollient). It's often used in makeup products mixed with silicones to give shine and slip to the product. It's also great for cleansing dirt and oil from the skin as well as for taking off make-up.

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

A common little helper ingredient that helps water and oil to mix together, aka emulsifier. 

The number at the end refers to the oil-loving part and the bigger the number  the more emulsifying power it has. 20 is a weak emulsifier, rather called solubilizer used commonly in toners while 60 and 80 are more common in serums and creams.

A white powdery thing that's the major component of glass and sand. In cosmetics, it’s often in products that are supposed to keep your skin matte as it has great oil-absorbing abilities. It’s also used as a helper ingredient to thicken up products or suspend insoluble particles. 

A vegetable origin (coconut or palm kernel oil and glucose) cleansing agent with great foaming abilities. It's also mild to the skin and readily biodegradable.

What-it-does: buffering

It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does emollient
irritancy, com. 0, 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
A handy spherical powder that gives excellent slip, fluidity and overall skin feel to the formula (often combined with Polymethylsilsesquioxane). [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does surfactant/cleansing
A type of silicone elastomer (rubber-like material with both viscosity and elasticity) whose major function is forming a nice film on the skin. [more]
what‑it‑does viscosity controlling
A big molecule used as a helper ingredient to form nice gel textures. [more]
what‑it‑does skin-identical ingredient | antioxidant | moisturizer/humectant
A special, "cross-linked" from of hyaluronic acid (HA). Claimed to have five times the water-binding capacity of normal HA, also acts as an antioxidant and gives skin long-term moisture. [more]
what‑it‑does moisturizer/humectant
Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does abrasive/scrub
what‑it‑does soothing
An exopolysaccharide secreted by a microorganism living in hydrothermal deep vents. It protects the skin against chemical, mechanical and UV aggressions. [more]
what‑it‑does cell-communicating ingredient
Protein fragments, aka peptides and growth factors derived from milk (whey). It is claimed to boost the production of important extracellular matrix components (the gooey stuff between the skin cells) such as hyaluronic acid, collagen I and fibronectin. [more]
what‑it‑does moisturizer/humectant
A type of sugar that has water-binding properties and helps to keep your skin hydrated. 
what‑it‑does skin-identical ingredient | moisturizer/humectant
The thing in the pee that is also a natural moisturizing factor (NMF) with mild keratolytic and strong skin moisturizing superpowers. [more]
what‑it‑does skin-identical ingredient
Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can d [more]
what‑it‑does viscosity controlling
irritancy, com. 4, 4
A large sugar molecule (aka polysaccharide) that's used as a gelling agent and comes from brown seaweed. Combined with calcium salts, it forms a rigid gel used in "rubber masks".  [more]
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
If you ever wondered what those little Listerine breath strips were made of, you found your answer! Pullulan is a polysaccharide polymer, which basically means that it’s a big molecule made up of smaller sugar molecule units. It dissolves in water and can make a thin, elastic, and moisture-absorbing film when spread on the skin that can cause an instant tightening effect. [more]
what‑it‑does buffering
what‑it‑does buffering
It’s a little helper ingredient that helps to set the pH of a cosmetic formulation to be just right. [more]
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
A spherical texturizing powder that's used as a texture enhancer and soft focus agent. [more]
what‑it‑does chelating | buffering
A helper ingredient that is used to adjust the pH of the product. Also helps to keep products stay nice longer by neutralizing the metal ions in the formula. 
what‑it‑does moisturizer/humectant | solvent
what‑it‑does emollient | emulsifying | surfactant/cleansing
A sugar ester (sucrose + palmitic acid) that works as a natural emulsifier. It also has a great skin-feel, improves smoothness, emolliency and even hydrates the skin. [more]
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does antioxidant
A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent.
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
what‑it‑does preservative
A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast. [more]
what‑it‑does buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
what‑it‑does emollient | solvent
A light, velvety, unique skin feel liquid that is a good solvent and also makes the skin feel nice and smooth. [more]
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0, 0
A common little helper ingredient that helps water and oil to mix together, aka emulsifier. [more]
what‑it‑does viscosity controlling
A white powdery thing that can mattify the skin and thicken up cosmetic products. [more]
what‑it‑does surfactant/cleansing
A vegetable origin (coconut or palm kernel oil and glucose) cleansing agent with great foaming abilities. It's also mild to the skin and readily biodegradable.
what‑it‑does buffering
It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]