Age Defy Concentrated Serum
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Safi Age Defy Concentrated SerumIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
A light-feeling, volatile (meaning it does not absorb into the skin but evaporates from it) silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A super versatile and common mineral powder that comes in different particle sizes. It is a multi-tasker used to improve skin feel, increase product slip, give the product light-reflecting properties, enhance skin adhesion or serve as an anti-caking agent.
It is also the most commonly used "base" material for layered composite pigments such as pearl-effect pigments. In this case, mica is coated with one or more metal oxides (most commonly titanium dioxide) to achieve pearl effect via the physical phenomenon known as interference.
We don't have description for this ingredient yet.
A superabsorbent polymer (big molecule from repeated subunits) that has crazy water binding abilities. Sometimes its referred to as "waterlock" and can absorb 100 to 1000 times its mass in water.
As for its use in cosmetic products, it is a handy multi-tasker that thickens up water-based formulas and also has some emulsifying and emulsion stabilizing properties.
A silicone emulsifier that helps to create water in silicone emulsions.
A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent.
A white, elastomeric silicone powder that gives a nice silky and powdery feel to the products. It also has some oil and sebum absorption capabilities.
Porous spherical microbeads (tiny little balls) that can give an elegant silky texture to the products. They are also used to scatter light to reduce the look of fine lines on the skin, as well as to absorb excess oil and give a matt finish.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Though its name does not reveal it, Carnosine is a peptide, a small, two amino acid (β-Ala-His) one. It is naturally present in high concentrations in muscle and brain tissues, but the one used in cosmetic products is biomimetic, meaning that it is synthetically produced in a lab to copy the natural thing.
A 2017 review paper on topical peptides writes about Carnosine that it is a "well-documented aqueous antioxidant with wound healing activity".
Other than that we can write about manufacturer-done in-vitro (in the lab, not on real people) studies that show Carnosine to have anti-glycation properties. Glycation is the not-so-nice process that happens when we bombard our body with too much sugar that results in damaged body proteins and eventually in more wrinkles.
Also, a manufacturer done in vitro study shows that carnosine might have collagen-boosing magic power. However, the 2017 research paper also mentions that even though Carnosine is a small molecule, it is water soluble and does not penetrate the skin past the top layers so we have some doubt if the collagen-boosting works in real life. We could find one anti-aging study made on real people that mentions Carnosine, but it was combined with a bunch of other anti-aging actives so it is pretty much impossible to know what Carnosine did or did not.
One last thing to mention is that there is also a manufacturer done clinical study (done on real people) that shows carnosine being effective against the damages caused by infrared (IR) radiation. (source)
An ingredient that is created from the attachment of the water-loving sugar molecule, glucose, and an oil-loving 20 carbon long fatty chain. This makes it a partly water- and partly oil-soluble material, meaning it functions as an emulsifier helping oil and water to mix.
Most often, it comes to the formula coupled with two fatty alcohol friends, Arachidyl and Behenyl alcohol, to make up an emulsifier trio trade named Montanov 202. As described by its manufacturer, the main thing of Montanonv 202 is that it gives creams a unique evanescent and light feel with a matt finish. It also leaves the skin soft, but not oily, is hypoallergenic and non-comedogenic making it perfect for both oily and sensitive skin formulas.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
Far from the tin cans you find in the supermarket, Tin Oxide is mostly used when dealing with so-called effect pigments, tricky composite pigments that can do color travel (change color depending on the viewing angle) or give multiple color effect.
It's often found alongside Mica (as a base material) and Titanium Dioxide (as a coating) to give a glossy, pearlescent effect. Together, they make up a trademarked technology called RonaFlair Blanace from the German manufacturer Merck. According to their info, this combination can balance out undesirable tones in the skin, making it a popular choice for brightening products and highlighters.
Other than that, CosIng (the official EU INCI database) lists its uses as being a bulking agent (to increase the volume of products), as well as a physical exfoliant or an opacifying agent, but being part of composite effect pigments is a much more common use case.
Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it in excruciating detail.
So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it THDA in short).
It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown. In addition, vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in the case of THDA, it's in-vitro and done by an ingredient supplier.
With this context in mind let's see what THDA might be able to do. First, it is stable (if pH < 5), easy to formulate, and a joy to work with for a cosmetic chemist.
Second, because it's oil-soluble, its skin penetration abilities seem to be great. So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the skin (that is usually important to do some anti-aging work). There is also in-vitro data showing that it converts to AA in the skin.
Third, THDA seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by more than 80% in human melanoma cell cultures.
So this all sounds really great, but these are only in-vitro results at this point. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% THDA. The authors theorized that the 10% AA is released slowly from the silicon delivery system and probably stays in the upper layer of the skin to give antioxidant benefits, while THDA penetrates more rapidly and deeply and gives some wrinkle-reducing benefits. The study was a small (10 patients), double-blind experiment, and the formula did show some measurable anti-aging results. However, it is hard to know how much pure vitamin C or THDA can be thanked.
Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet).
A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.
It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration.
The GHK part is the important one as it's a type I collagen fragment. When collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more.
Therefore, Palmitoyl Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin.
In Matrixyl 3000, Palmitoyl Tripeptide-1 is coupled with Palmitoyl Tetrapeptide-7 and the duo works in synergy to reduce wrinkles and give younger looking skin. According to the manufacturer's in-vivo (made on real people) test, applying 3% Matrixyl 3000 twice a day for 2 months resulted in all of the following things:
- 39.4% reduction in surface occupied by deep wrinkles
- 32.9% reduction in main wrinkle density
- 19.9% reduction in main wrinkle average depth
- 16% improvement in roughness
- 16.2% in lifting effect
- 5.5% improvement in elasticity
- 15.5% improvement in skin tone
Manufacturer results, of course, always have to be taken with a pinch of salt, but if you like peptides, the Matryxil 3000 duo is one of the best-proven and most well-known ones and it's something that is worth trying.
A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration.
It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time.
It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. It's often combined with IT-preservative, phenoxyethanol.
Ci 77891 is the color code of titanium dioxide. It's a white pigment with great color consistency and dispersibility.
Red Iron Oxide is the super common pigment that gives the familiar, "rust" red color. It is also the one that gives the pink tones in your foundation. Chemically speaking, it is iron III oxide (Fe2O3).
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| what‑it‑does | solvent |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emollient | solvent |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | colorant |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | emulsifying |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | antioxidant | cell-communicating ingredient |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | chelating |
| what‑it‑does | colorant | abrasive/scrub | viscosity controlling |
| what‑it‑does | antioxidant | skin brightening |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | antimicrobial/antibacterial |
| what‑it‑does | perfuming |
| what‑it‑does | preservative |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | preservative | antimicrobial/antibacterial |
| what‑it‑does | colorant |
| irritancy, com. | 0, 0 |
| what‑it‑does | colorant |
| irritancy, com. | 0, 0 |