Advanced Anti-aging C-pdrn® + Retinol Serum
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Rejuran Advanced Anti-aging C-pdrn® + Retinol SerumIngredients explained
Aloe Vera is one of today’s magic plants. It does have some very nice properties indeed, though famous dermatologist Leslie Baumann warns us in her book that most of the evidence is anecdotal and the plant might be a bit overhyped.
What research does confirm about Aloe is that it’s a great moisturizer and has several anti-inflammatory (among others contains salicylates, polysaccharides, magnesium lactate and C-glucosyl chromone) as well as some antibacterial components. It also helps wound healing and skin regeneration in general. All in all definitely a goodie.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Cucumber is a nice, non-irritating plant extract that’s known for it’s soothing and emollient properties. It’s not something new to put it on our face: even Cleopatra used it to “preserve her skin”.
It’s commonly believed that cucumber is the answer to puffy eyes, but there is no research confirming this. What research does confirm is that it contains amino acids and organic acids that’s helpful for the skin’s acid mantle. There is also an enzyme (called shikimate dehydrigenase) in the pulp that’s shown to have anti-inflammatory properties.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
We don't have description for this ingredient yet.
We feel that this one is a bit under the radar probably because the Borage plant is not very well known. Maybe because its name isn't as cool as some others, it's hard to compete with kukui or baobab, not to mention murumuru. But let us tell you when it comes to skin care, borage seed oil is one of the best oils that can happen to your skin. Especially, if it's dry, sensitive, easily irritated, often itchy or eczema prone.
So what is so special about it? It is the richest known plant source of the super important essential fatty acid, gamma-linolenic acid (GLA). GLA is soothing and nourishing, and can repair even severely dry and irritated skin, but it's pretty rare and borage contains by far the most of it (17-28%). Next to GLA, it also contains more common fatty acids, like linoleic (36%), oleic (18%) or palmitic acid (10%).
If your skin is dry and sensitive, this one is totally for you.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
When it comes to cosmetic oils and hype, argan oil is for sure leading the way. Dubbed as the "liquid gold of Morocco", we have to admit we have some trouble determining why this oil enjoys such a special miracle status. Not that it's not good, it is good, even great but reading the research about argan and a bunch of other plant oils we just do not see the big, unique differentiating factor (though that might be our fault not reading enough, obvs.)
So, argan oil comes from the kernel of the argan fruit that comes from the argan tree that grows only in Morocco. The tree is slow growing and getting the oil is a hard job. The traditional process is that the ripe argan fruits fall from the tree, then goats eat them up and poop out the seeds. The seeds are collected and smashed with a stone to get the kernels inside. This part is the hard one as the seeds have extremely hard shells. Once the kernels are obtained, the oil is pressed out from them (the kernels contain about 50% oil).
As for skincare, argan oil is loaded with lots of skin goodies (but so are many other plant oils): it contains 80% nourishing and moisturizing unsaturated fatty acids, mainly oleic (38-50%), linoleic (28-38%) and palmitic (10-18%). It also contains a relatively large amount of antioxidant vitamin E (600-900 mg/kg, about twice as much as olive), small amounts of antioxidant phenols (including caffeic acid, ferulic acid, and epicatechin), as well as some rare sterols with soothing and anti-inflammatory properties.
Thanks to all the above goodness in argan oil, it can greatly nourish and moisturize the skin and hair. It's also claimed to be able to neutralize collagen-damaging free radicals, help reduce scars, and revitalize and improve skin elasticity. You can even read that argan might help acne-prone skin, but being a high oleic oil, we would be careful with that.
All in all, argan oil is a real goodie but we do not fully understand the special miracle status it enjoys.
The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.
Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. One solution is to create stable derivatives that can be absorbed into the skin, convert there to AA and do all the magic AA is proven to do (which is being an antioxidant, a collagen booster, and a skin brightener).
SAP (the vit C derivative, not the enterprise software, obvs) is a promising derivative that has great stability up to pH 7. The challenge with it though is skin penetration. Unfortunately, it seems to be limited, or to quote a great article from the Journal of Cosmetic Dermatology "topically applied ascorbyl phosphate salts are, at very best, poorly absorbed in comparison with AA". Regarding conversion to AA, there seems to be no data about it, so we can neither deny nor confirm it.
We have better news regarding the three magic abilities of vitamin C: there is in-vivo (tested on real people) data showing that SAP does have photo-protective (aka antioxidant) properties, though less than pure AA. SAP might also aid collagen boosting; in-vitro (made in the lab) data shows that it works, but is less effective than another vitamin C derivative, called MAP (that seems to be as effective as pure AA). As for skin-brightening, there is a trade publication with in-vivo data showing that SAP can fade brown spots.
Another thing SAP might be able to do is to help with acne. A 2005 study showed in vitro (in test tubes) that 1% SAP has a strong antimicrobial activity on evil acne causing P. acnes and it also showed in vivo (on real people) that 5% SAP can strongly improve the inflammatory and non-inflammatory lesions of acne vulgaris. In fact, the results were comparable or even slightly better than with 5% benzoyl peroxide.
And there is even more regarding SAP and acne. A nice double-blind study from 2009 showed that 5% SAP reduced the inflammatory lesions by 20.14% and 48.82% within 4 and 8 weeks respectively and when combined with 0.2% retinol the results were even better. With this combination treatment, the improvement was 29.28% after 4 weeks and 63.10% after 8 weeks of application.
Aside from research studies, anecdotal evidence also supports SAP being a promising vitamin C derivative. One of the best-selling (vitamin C) serums in Sephora is the Ole Henriksen Truth Serum, while on Amazon it's the OzNaturals Vitamin C 20 Serum. Another popular choice is the Mad Hippie Vitamin C serum, and all of these contain vitamin C in the form of SAP.
Overall, we think SAP is a goody! In terms of anti-aging, it's probably not as effective as pure Ascorbic Acid, but it's totally worth a try. However, if your skin is acne-prone, SAP is your form of Vitamin C and it's a must-try.
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
We don't have description for this ingredient yet.
Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:
- It can help with wound healing
- It’s a good anti-inflammatory agent
- It might even help with skin’s own collagen production and improve skin firmness and elasticity
- It helps with barrier repair and protection
- It might be even useful for the hair helping with hair thickness and hair growth
- Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
- It has to be converted in the skin to retinoic acid to work its magic
- Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
- A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
- It makes skin less wrinkled, smoother, firmer and tighter
- It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
- Possible side effects and irritation are also much less than with retinoic acid
- Do not use whilst pregnant
It's a pretty new peptide trade-named MATRIXYL™ synthe’6. The manufacturer claims that it can boost the production of 6 major components of the skin matrix (collagen I, III, IV, fibronectin, hyaluronic acid and laminin 5) that result in more even skin and fewer wrinkles particularly on the forehead and crow's feet. Using 2% of the active for two months daily, women reported a decrease in wrinkles by 31% up to 100%.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
A nice little helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. It's derived from cellulose, the major component of the cell wall of green plants. It is compatible with most co-ingredients and gives a very good slip to the formulas.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
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what‑it‑does | soothing | moisturizer/humectant |
what‑it‑does | soothing |
what‑it‑does | soothing | emollient |
what‑it‑does | emollient |
what‑it‑does | perfuming | viscosity controlling |
what‑it‑does | soothing | emollient |
what‑it‑does | soothing | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | soothing | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | antioxidant | emollient |
what‑it‑does | antioxidant | anti-acne |
what‑it‑does | soothing |
irritancy, com. | 0, 0 |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | viscosity controlling |
what‑it‑does | viscosity controlling |
what‑it‑does | viscosity controlling |
irritancy, com. | 0, 1 |
what‑it‑does | emollient |
irritancy, com. | 0, 1 |
what‑it‑does | solvent |
what‑it‑does | preservative |