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Prana Spaceuticals Don't Cramp On Me Cream

Don't Cramp On Me Cream

This cream helps to alleviate pms discomfort.
Uploaded by: hannahh on

Prana Spaceuticals Don't Cramp On Me Cream
Ingredients explained

Also-called: Aqua;Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Also-called: Aloe Leaf Extract;Aloe Barbadensis Leaf Extract | What-it-does: soothing, emollient, moisturizer/humectant

The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though  oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.

Coconut Oil - goodie
Also-called: Cocos Nucifera Oil | What-it-does: emollient, perfuming | Irritancy: 0 | Comedogenicity: 4

There is definitely some craze going on for coconut oil both in the healthy eating space (often claimed to be the healthiest oil to cook with but this is a topic for another site) and in the skin and hair care space. 

We will talk here about the latter two and see why we might want to smear it all over ourselves. Chemically speaking, coconut oil has a unique fatty acid profile. Unlike many plant oils that mostly contain unsaturated fatty acids (fatty acids with double bonds and kinky structure such as linoleic or oleic), coconut oil is mostly saturated (fatty acids with single bonds only) and its most important fatty acid is Lauric Acid (about 50%).  Saturated fatty acids have a linear structure that can stack nice and tight and hence they are normally solid at room temperature. Coconut oil melts around 25 °C so it is solid in the tub but melts on contact with the skin. 

Also-called: Methylsulfonylmethane, MSM;Dimethyl Sulfone

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant

A chemically chopped up version of wheat protein that consists mainly of amino acids (the building blocks), peptides (a couple of amino acids together), and proteins (lots of amino acids together). 

It has moisturizing and film-forming properties and  might be able to counteract the irritating effects of cleansing agents in cleansers and shampoos. It can also condition and repair damaged hair leaving it soft, silky and smooth.

What-it-does: emollient, viscosity controlling | Irritancy: 0 | Comedogenicity: 2-3

A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).

Also-called: Evening Primrose Oil, EPO;Oenothera Biennis Oil | What-it-does: soothing, emollient | Irritancy: 2 | Comedogenicity: 3

The oil coming from the seeds of the nice, little, yellow-flowered plant called Evening Primrose. Similar to other plant oils, it's loaded with nourishing and moisturizing fatty acids. It's a very rich source of linoleic acid (66-76%), and also contains the soothing and healing superstar fatty acid, gamma-linolenic acid (aka GLA, 7-12%) (Btw, the richest known source of GLA is the borage oil, but evening primrose still counts as a very good source of it). It also contains oleic acid, but not too much around 6-15%.

Since the 1980's, EPO is a well-known food supplement and there are quite a lot of studies examining what happens if you take it orally. It seems to be helpful with a bunch of  things: atopic dermatitis, dry eyes, brittle nails, sunburn and even acne.

Shea Butter - goodie
Also-called: Butyrospermum Parkii Butter | What-it-does: emollient

Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.

But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat. 

Also-called: Tocopheryl Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

  • It’s naturally in our skin and behaves there like a sponge
  • It can bind up to 1000 times its own weight in water
  • It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
  • High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
  • Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
  • Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
  • Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
Read all the geeky details about Hyaluronic Acid here >>

What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

Lecithin - goodie
What-it-does: emollient, emulsifying

A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes

Also-called: Green Tea;Camellia Sinensis Leaf Extract | What-it-does: antioxidant, soothing
  • Green tea is one of the most researched natural ingredients
  • The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
  • There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
  • Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
  • Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis
Read all the geeky details about Camellia Sinensis Leaf Extract here >>

Also-called: Horse Chestnut;Aesculus Hippocastanum Seed Extract | What-it-does: soothing

Horse Chestnut is an often-used ingredient thanks to a couple of nice magic properties. It contains the active ingredient called escin that helps to maintain healthy blood circulation and strengthen capillaries. This makes horse chestnut useful for rosacea-prone skin and it’s also often used in toners for a fresh skin feeling. 

It also has some anti-inflammatory and wound healing properties, so all in all, a nice one to spot on the ingredient list. 

Witch Hazel - goodie
Also-called: Witch Hazel Extract;Hamamelis Virginiana Extract | What-it-does: soothing, antioxidant, antimicrobial/antibacterial, astringent

Witch hazel is a smallish tree (up to 5m) that's native to North-America, has nice yellow flowers and is similar to the hazelnut bush (hence the name).  

As for skincare, it's loaded with active components that have a bunch of magic properties, like astringent, anti-inflammatory, antioxidant and anti-bacterial. It's also a well-known vasoconstrictor (it makes the blood vessels narrower) and promotes the healing of broken skin by tightening up the skin proteins and thus creating a protective covering.

Also-called: Calendula Extract, Marigold Extract;Calendula Officinalis Extract | What-it-does: soothing, antioxidant

The extract coming from the popular garden plant Calendula or Marigold. It's used traditionally as a skin-repairing and soothing plant extract

Click here to read more at the calendula flower extract

We don't have description for this ingredient yet.

Also-called: Symphytum Officinale Root Extract | What-it-does: soothing

A medicinal plant with analgesic (painkilling) and anti-inflammatory magic properties. It contains allantoin and rosmarinic acid that are probably responsible for its soothing power. It's often used in the field of sports for treating bruises or sprains.

The questionable side of comfrey (that prevented us from giving it a goodie rating) is that it also contains pyrrolizidine alkaloids (PA). That guy has some proven toxic effect so for example in Germany the permissibale dose of PA is 100 μg/day and if the dose is between 10-100 μg/day the treatment is limited to 4-6 weeks per year.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Vitis Vinifera Seed Extract | What-it-does: antioxidant, antimicrobial/antibacterial

We wholeheartedly support the rise of seedless grapes as fruit snacks, but when it comes to skincare, we are big fans of the seeds.

They contain the majority of the skin goodies that -  similar to green tea - are mostly polyphenols (but not the same ones as in tea). The most abundant ones in grape are called proanthocyanidins, and 60-70% of them are found in the seeds (it's also often abbreviated as GSP - grape seed proanthocyanidins). In general, the darker the fruit, the more GSPs and other flavonoids it contains.

Also-called: Peppermint Oil;Mentha Piperita Oil | What-it-does: perfuming

The essential oil coming from steam distillation of freshly harvested, flowering peppermint sprigs. Its major component is menthol that gives the oil its well-known refreshing and cooling properties. Peppermint oil is traditionally used as an inhalant for cold and coughs and there is also some clinical data validating its use against headaches by rubbing a peppermint oil cream on the forehead. 

As for skincare, other than the nice grassy-minty smell and the refreshing sensations, we cannot write good things. It can be a skin irritant, so much so that it is a well-known counterirritant for muscle pains creating mild surface irritation to make things better in the deeper layers. But for everyday skincare, counterirritation is not something you wanna do, so we think that peppermint oil is better to avoid, especially if your skin is sensitive. 

Also-called: Palmarosa Oil;Cymbopogon Martini Oil

We don't have description for this ingredient yet.

Also-called: Eucalyptus Globulus Leaf Oil | What-it-does: perfuming, antimicrobial/antibacterial

The essential oil created by steam distilling the leaves of the Eucalyptus tree. It's a colorless, pale yellow oil with a camphoraceous aroma used traditionally in vapor rubs to treat coughs. Its name-giving main component is eucalyptol (also called 1,8-cineole, 80-91%) that has significant antibacterial and expectorant properties.   

Among essential oils, Eucalyptus Globulus counts as rather non-sensitising with an EU sensitizer total of 5% (due to limonene). However, if your skin is super-sensitive or you are allergic to fragrances, it is still better to avoid it. 

Also-called: Lemon Peel Oil;Citrus Limon Peel Oil | What-it-does: perfuming

The essential oil coming from the rind of the lemon that we make (or should make) lemonade from. In general, there are two problems with citrus peel oils: first, they are essentially the fragrant component, limonene in disguise (they are about 85-98% limonene).

Second, they contain the problematic compounds called furanocoumarins that make them mildly phototoxic. Lemon peel contains a medium amount of them, more than sweet orange but less than bergamot. Be careful with it especially if it is in a product for daytime use.  

Also-called: Lavandula Angustifolia Oil | What-it-does: antimicrobial/antibacterial, perfuming

We have to start by writing how fascinated we are by the amazing lavender fields of Provance and we do love pretty much everything about lavender: its look, its color, its scent.... but, when it comes to skincare, lavender is a questionable ingredient that you probably do not want in your skincare products.

First, let us start with the pros: it has a lovely scent, so no wonder that it is popular as a fragrance ingredient in natural products wanting to be free from synthetic fragrances but still wanting to smell nice. The scent of lavender is famous for having calming and relaxing properties and some smallish scientific studies do support that. Inhaled volatile compounds seem to have a soothing effect on the central nervous system and studies have shown that lavender aromatherapy can improve patient's anxiety and experience in hospitals.   

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does soothing | emollient | moisturizer/humectant
The extract coming from the juice containing leaves of the Aloe vera plant with moisturizing, emollient and anti-inflammatory properties. [more]
what‑it‑does emollient | perfuming
irritancy, com. 0, 4
There is definitely some craze going on for coconut oil both in the healthy eating space (often claimed to be the healthiest oil to cook with but this is a topic for another site) and in the skin and hair care space. We will talk here about the latter two and see why we might want to smear it all over ourselves. [more]
what‑it‑does moisturizer/humectant
A chemically chopped up version of wheat protein with moisturizing and film-forming properties. [more]
what‑it‑does emollient | viscosity controlling
irritancy, com. 0, 2-3
A common multi-tasker fatty acid that works as an emollient, thickener and emulsion stabilizer. [more]
what‑it‑does soothing | emollient
irritancy, com. 2, 3
An emollient plant oil loaded with nourishing and moisturizing fatty acids. It's a very rich source of linoleic acid (66-76%), and also contains the soothing and healing superstar fatty acid, gamma-linoleic acid. [more]
what‑it‑does emollient
Shea butter that's considered to be a magic moisturizer and emollient. It is also soothing and rich in antioxidants. [more]
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0, 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
what‑it‑does emollient | emulsifying
It's quite the multi-tasker: an emollient and water-binding ingredient but also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.  [more]
what‑it‑does antioxidant | soothing
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
what‑it‑does soothing
Horse Chestnut - contains the active called escin that helps to maintain healthy blood circulation and strengthen capillaries and veins. It also has some anti-inflammatory and wound healing properties. [more]
what‑it‑does soothing | antioxidant | antimicrobial/antibacterial
With Hazel - loaded with active components (hamamelitannin, catechins, gallic acid) that have astringent, anti-inflammatory, antioxidant or anti-bacterial properties. Also well-known vasoconstrictor and promotes skin healing. [more]
what‑it‑does soothing | antioxidant
Marigold extract - used traditionally as a skin-repairing and soothing plant extract.  [more]
what‑it‑does soothing
A medicinal plant with analgesic (painkilling) and anti-inflammatory properties. Often used for treating bruises or sprains. Also, contains a toxic compound called pyrrolizidine alkaloids (PA), but most probably your skincare product contains so minuscule amount of PA (less than 10 μg/day) that it's not a problem. [more]
what‑it‑does antimicrobial/antibacterial | soothing
what‑it‑does antioxidant | antimicrobial/antibacterial
Grape Seed Extract - contains awesome polyphenols that are super-potent antioxidants and also have UV-protecting and anti-cancer properties. [more]
what‑it‑does perfuming
The essential oil coming from steam distillation of freshly harvested, flowering peppermint sprigs. Its major component is menthol that gives the oil its well-known refreshing and cooling properties. [more]
what‑it‑does perfuming | antimicrobial/antibacterial
The essential oil created by steam distilling the leaves of the Eucalyptus tree. It's a colorless, pale yellow oil with a camphoraceous aroma used traditionally in vapor rubs to treat coughs. [more]
what‑it‑does perfuming
The essential oil coming from the rind of the lemon. Its main component (83-97%) is limonene, the super common fragrant ingredient. [more]
what‑it‑does antimicrobial/antibacterial | perfuming
Lavender - essential oil with a calming scent and antimicrobial properties. Contains fragrant components (linalyl acetate - 50% and linalool - 35%) and might be cytotoxic from 0.25%. [more]