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MG 3 Peptides + Ferment

MG
3 Peptides + Ferment

Uploaded by: ryticle on 03/06/2019

Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

Bifida Ferment Lysate is a probiotic ingredient that’s used in one of the most iconic serums in the world, the Estee Lauder Advanced Night Repair. Based on manufacturer info it potently protects against UV-induced damage in the skin and helps with DNA repair. An Estee Lauder patent from 2009 also talks about DNA repair activity.

As far as published research goes we could find one promising one. It showed that applying 10% bacterial extract to sensitive, reactive skin helped with better barrier function and decreased skin sensitivity

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Overall, it is definitely a promising ingredient, even for sensitive skin types but not the most proven one (yet).

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

Alcohol - icky
Also-called: Ethanol | What-it-does: antimicrobial/antibacterial, solvent, viscosity controlling, astringent

Simply alcohol refers to ethanol and it's a pretty controversial ingredient. It has many instant benefits: it's a great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial. No wonder it's popular in toners and oily skin formulas. 

The downside is that it can be very drying if it's in the first few ingredients on an ingredient list. 

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Some experts even think that regular exposure to alcohol damages skin barrier and causes inflammation though it's a debated opinion. If you wanna know more, we wrote a more detailed explanation about what's the deal with alcohol in skincare products at alcohol denat. (it's also alcohol, but with some additives to make sure no one drinks it).

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the cheapest and most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

What-it-does: buffering

We don't have description for this ingredient yet.

What-it-does: preservative

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4). 

But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.

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BTW, it’s also a food preservative and even has an E number, E202.

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

What-it-does: emollient

A clear, slightly yellow, odorless oil  that's a very common, medium-spreading emollient. It makes the skin feel nice and smooth and works in a wide range of formulas.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

There is not much info about this guy in itself other than it helps to thicken up products and stabilize oil-in-water emulsions. It usually comes to the formula as part of some thickener complex. For example, coupled with isohexadecane and polysorbate 80, the trio forms an instant gel upon mixing with water. 

Parfum - icky
Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face than fragrance is not your best friend - no way to know what’s really in it.  

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Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!). 

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

Tocopherol - superstar
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: emulsifying

A mild, water-loving emulsifier that's safe for sensitive skin or eye-care formulations. It helps to create low viscosity oil-in-water emulsions, ideal for milks, serums, and sprayable formulations. It's derived from natural sources and  gives a light, satiny afterfeel.    

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little of xanthan gum will make it more gel-like.  Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

Adenosine - goodie

Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:

  • It can help with wound healing
  • It’s a good anti-inflammatory agent
  • It might even help with skin’s own collagen production and improve skin firmness and elasticity
  • It helps with barrier repair and protection
  • It might be even useful for the hair helping with hair thickness and hair growth
Citric Acid - goodie
What-it-does: exfoliant, buffering

Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA. 

So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh. 

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There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin. 

But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation. 

What-it-does: buffering | Irritancy: 0 | Comedogenicity: 2

It’s a little helper ingredient that helps to set the pH of a cosmetic formulation to be just right. It’s very alkaline (you know the opposite of being very acidic): a 1% solution has a pH of around 10.

It does not have the very best safety reputation but in general, you do not have to worry about it. 

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What is true is that if a product contains so-called N-nitrogenating agents (e.g.: preservatives like 2-Bromo-2-Nitropropane-1,3-Diol, 5-Bromo-5-Nitro- 1,3-Dioxane or sodium nitrate - so look out for things with nitro, nitra in the name) that together with TEA can form some not nice carcinogenic stuff (that is called nitrosamines). But with proper formulation that does not happen, TEA in itself is not a bad guy. 

But let’s assume a bad combination of ingredients were used and the nitrosamines formed. :( Even in that case you are probably fine because as far as we know it cannot penetrate the skin. 

But to be on the safe side, if you see Triethanolamine in an INCI and also something with nitra, nitro in the name of it just skip the product, that cannot hurt.

We don't have description for this ingredient yet.

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

We don't have description for this ingredient yet.

Also-called: Pineapple Fruit Extract | What-it-does: soothing, moisturizer/humectant

A goodie fruit extract coming from the lovely pineapple. It contains a bunch of good-for-the-skin stuff:  bromelain and fruit acids  have mild exfoliant properties, and fruit sugars and amino acids give the pineapple fruit nice moisturizing and soothing properties. 

There is also a pineapple extract called pineapple ceramide on the market that's claimed to be loaded with a glucose linked ceramide derivative called glucoceramide. According to the manufacturer, glucoceramide is not only a skin moisturizer but it also helps to lighten the skin and make it more smooth.

Irritancy: 0 | Comedogenicity: 0

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Carnosine - goodie

Though its name does not reveal it, Carnosine is a peptide, a small, two amino acid (β-Ala-His) one. It is naturally present in high concentrations in muscle and brain tissues, but the one used in cosmetic products is biomimetic, meaning that it is synthetically produced in a lab to copy the natural thing. 

A 2017 review paper on topical peptides writes about Carnosine that it is a "well-documented aqueous antioxidant with wound healing activity".  

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Other than that we can write about manufacturer-done in-vitro (in the lab, not on real people) studies that show Carnosine to have anti-glycation properties. Glycation is the not-so-nice process that happens when we bombard our body with too much sugar that results in damaged body proteins and eventually in more wrinkles.  

Also, a manufacturer done in vitro study shows that carnosine might have collagen-boosing magic power. However, the 2017 research paper also mentions that even though Carnosine is a small molecule, it is water soluble and does not penetrate the skin past the top layers so we have some doubt if the collagen-boosting works in real life. We could find one anti-aging study made on real people that mentions Carnosine, but it was combined with a bunch of other anti-aging actives so it is pretty much impossible to know what Carnosine did or did not. 

One last thing to mention is that there is also a manufacturer done clinical study (done on real people) that shows carnosine being effective against the damages caused by infrared (IR) radiation. (source)

We don't have description for this ingredient yet.

Also-called: Syn-Ake | What-it-does: cell-communicating ingredient

This awfully long named ingredient is, in fact, a pretty small molecule. It's a tripeptide (a three amino acid peptide)  with molecular weight less than 500 Da, meaning that it's small enough to penetrate nicely and easily into the skin.

It belongs to the "Botox in a jar" type of peptides (similar to Argireline or Leuphasyl) targeting wrinkles caused by facial movements, like laughter lines or crow’s feet. According to the manufacturer's in-vivo (made on real people) studies, 4% Syn-Ake used for 28 days resulted in 21% smoother and 15-20% less wrinkled skin with max values up to 52%. The smoothing effect was measurable on 80% of the volunteers, while the wrinkle reduction effect was evident on 73%.

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
A probiotic ingredient that might protect against UV-induced damage, help barrier repair and decrease skin sensitivity. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]
what‑it‑does antimicrobial/antibacterial | solvent | viscosity controlling
Simple alcohol that's a great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent, and antimicrobial. In large amount can be very drying. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does emollient
irritancy, com. 0, 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
what‑it‑does buffering
what‑it‑does preservative
A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast. [more]
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]
what‑it‑does moisturizer/humectant
what‑it‑does emollient
A clear, slightly yellow, odorless oil  that's a very common, medium-spreading emollient. It makes the skin feel nice and smooth and works in a wide range of formulas.
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
what‑it‑does viscosity controlling
A polymer that helps to thicken up products and stabilize oil-in-water emulsions. [more]
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does emulsifying
A mild, water-loving emulsifier that's safe for sensitive skin or eye-care formulations. It helps to create low viscosity oil-in-water emulsions. [more]
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does cell-communicating ingredient
An important compound in our body that has a vital cell-signalling role. It is wound healing, anti-inflammatory and can help with barrier repair. [more]
what‑it‑does exfoliant | buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
what‑it‑does buffering
irritancy, com. 0, 2
Helps to set the pH of a cosmetic formulation to be right. It’s very alkaline. [more]
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
what‑it‑does moisturizer/humectant | solvent
what‑it‑does soothing | moisturizer/humectant
Pineapple fruit extract that contains moisturizing and soothing fruit sugars and amino acids and mildly exfoliant fruit acids. [more]
irritancy, com. 0, 0
what‑it‑does antioxidant | cell-communicating ingredient
A biomimetic peptide with antioxidant, anti-glycation and maybe collagen boosting abilities. It also protects against damages caused by infrared radiation. [more]
what‑it‑does cell-communicating ingredient
A three amino-acid, small peptide that belongs to the "botox in a jar" type of peptides. It can smooth wrinkles caused by facial movements, like laughter lines or crow’s feet. [more]