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md formula P.H.D Coldtox Pro-Active Facial Serum

Coldtox Pro-Active Facial Serum

A light serum that works to cool, firm and protect the skin
Uploaded by: sundari.uk on

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Aqua (Water) solvent
Polysilicone-11
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Maltodextrin
Sodium Polyacrylate viscosity controlling, emollient
Benzyl Alcohol preservative, perfuming, solvent, viscosity controlling
Butylene Glycol moisturizer/​humectant, solvent, viscosity controlling 0, 1
Hydrogenated Polydecene emollient, perfuming, solvent
Salicylic Acid exfoliant, anti-acne, soothing, preservative superstar
Creatine
Phenoxyethanol preservative
Menthol soothing icky
Parfum (Fragrance) perfuming icky
Macrocystis Pyrifera Extract
Laureth-12 emulsifying, surfactant/​cleansing
Collagen Amino Acids skin-identical ingredient, moisturizer/​humectant goodie
Alcohol antimicrobial/​antibacterial, solvent, viscosity controlling icky
Menthyl Lactate
Hydrolyzed Wheat Protein moisturizer/​humectant goodie
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
PVP viscosity controlling 0, 0
Disodium EDTA chelating
Trideceth-6 emulsifying, surfactant/​cleansing
Dehydroacetic Acid preservative
Lecithin emollient, emulsifying goodie
Carbomer viscosity controlling 0, 1
Benzyl Salicylate perfuming icky
Ethylhexylglycerin preservative
Hexyl Cinnamal perfuming icky
Polysorbate 20 emulsifying, surfactant/​cleansing 0, 0
Limonene perfuming, solvent icky
Potassium Sorbate preservative
Chlamydocapsa Extract
Palmitoyl Tripeptide-1 cell-communicating ingredient goodie
Palmitoyl Tetrapeptide-7 cell-communicating ingredient goodie

md formula P.H.D Coldtox Pro-Active Facial Serum
Ingredients explained

Also-called: Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

A type of silicone elastomer (rubber-like material with both viscosity and elasticity) whose major function is forming a nice film on the skin.

It is also cosmetically very elegant with a non-tacky, non-oily and smooth skin feel. It also works as a stable delivery system of active materials, has sebum absorption and control properties and upon application, it transforms into a matte appearance with a powdery after feel.

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding). 

A superabsorbent polymer (big molecule from repeated subunits) that has crazy water binding abilities. Sometimes its referred to as "waterlock" and can absorb 100 to 1000 times its mass in water. 

As for its use in cosmetic products, it is a handy multi-tasker that thickens up water-based formulas and also has some emulsifying and emulsion stabilizing properties. 

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.

No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.  

What-it-does: moisturizer/humectant, solvent, viscosity controlling | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

Also-called: Alphaflow | What-it-does: emollient, perfuming, solvent

A hydrocarbon-based emollient that can come in different viscosities from silky-light through satiny-smooth to luxurious, rich. It forms a non-occlusive film on the surface of the skin and brings gloss without greasiness to the formula. It's a very pure and hypoallergenic emollient that's also ideal for baby care products. 

Salicylic Acid - superstar
Also-called: BHA | What-it-does: exfoliant, anti-acne, soothing, preservative
  • It's one of the gold standard ingredients for treating problem skin
  • It can exfoliate skin both on the surface and in the pores
  • It's a potent anti-inflammatory agent
  • It's more effective for treating blackheads than acne
  • For acne combine it with antibacterial agents like benzoyl peroxide or azelaic acid
Read all the geeky details about Salicylic Acid here >>

We don't have description for this ingredient yet.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

Menthol - icky
What-it-does: soothing

Menthol needs no introduction: it's the thing that causes the cooling sensation so well-known both from cosmetic products as well as a bunch of other things like chocolate, chewing gum, toothpaste or cigarette. It's a natural compound that comes from the essential oil of Mentha species (peppermint oil contains 40-50% menthol) and it gives them their typical minty smell and flavor.

As for skincare, menthol seems to be a mixed bag. Apart from the cool cooling sensation (that might last up to 70 mins!), it also has painkilling, itch reducing, antibacterial, antifungal and even penetration enhancing properties. On the other hand, it also seems to act as a skin irritant that increases trans-epidermal water loss (the water that evaporates from the outer layer of the skin) and thus contributes to drying out the skin.

Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.  

Also-called: Kelp Extract

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Amino acids are important natural moisturizing factors (NMFs), that can be found naturally in the skin where they help the epidermis (upper layer of the skin) to stay nice and hydrated

Amino acids are also the building blocks of proteins, such as collagen, so when you thoroughly chop up a big collagen molecule, you end up with an amino acid mixture, like this guy we are writing about. Btw, if you chop it up less thoroughly, you get hydrolyzed collagen, a kind of peptide mixture with smallish chains of amino acids. 

Alcohol - icky
Also-called: Ethanol | What-it-does: antimicrobial/antibacterial, solvent, viscosity controlling, astringent

Simply alcohol refers to ethanol and it's a pretty controversial ingredient. It has many instant benefits: it's a great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial. No wonder it's popular in toners and oily skin formulas. 

The downside is that it can be very drying if it's in the first few ingredients on an ingredient list. 

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant

A chemically chopped up version of wheat protein that consists mainly of amino acids (the building blocks), peptides (a couple of amino acids together), and proteins (lots of amino acids together). 

It has moisturizing and film-forming properties and  might be able to counteract the irritating effects of cleansing agents in cleansers and shampoos. It can also condition and repair damaged hair leaving it soft, silky and smooth.

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

Also-called: Poly Vinyl Pyrollidone | What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 0

These three letters stand for Poly Vinyl Pyrollidone, a big molecule created from repeated units of Vinyl Pyrrolidone, aka VP. Its main thing is being an important film former. It was the first synthetic polymer introduced as a hair fixative in the 1950s instead of insect-derived Shellac. 

So PVP likes to attach itself to surfaces such as the hair and the skin and forms a nice, thin, even film there. The film is useful for holding a hairstyle or extending the wear of color cosmetics and sunscreens. The disadvantage of PVP is that the film is a bit brittle and that PVP loves water (hygroscopic) that tends to destroy the film. This is the reason why hair styled with a PVP based product loses its style in high humidity. To fix this problem, there are now several versions of VP containing film formers that are less sensitive to humidity, for example, the molecule called VP/VA Copolymer

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

We don't have description for this ingredient yet.

Also-called: Geogard 111A | What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi and has only milder effect against bacteria. 

It is Ecocert and Cosmos approved, works quite well at low concentrations (0.1-0.6%) and is popular in natural products.

Lecithin - goodie
What-it-does: emollient, emulsifying

A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes

What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 1

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

What-it-does: perfuming

It’s a common fragrance ingredient that has a light floral smell.  It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid if your skin is sensitive.

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

What-it-does: perfuming

A common fragrance ingredient that smells like jasmine. It is one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. Best to avoid if your skin is sensitive.

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

Limonene - icky
What-it-does: perfuming, solvent, deodorant

A super common and cheap fragrance ingredient. It's in many plants, e.g. rosemary, eucalyptus, lavender, lemongrass, peppermint and it's the main component (about 50-90%) of the peel oil of citrus fruits.

It does smell nice but the problem is that it oxidizes on air exposure and the resulting stuff is not good for the skin. Oxidized limonene can cause allergic contact dermatitis and counts as a frequent skin sensitizer

What-it-does: preservative

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4). 

But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.

We don't have description for this ingredient yet.

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinterleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
A type of silicone elastomer (rubber-like material with both viscosity and elasticity) whose major function is forming a nice film on the skin. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding). 
what‑it‑does viscosity controlling | emollient
A big polymer (a molecule from repeated subunits) with crazy water binding abilities. Used as a thickening and emulsion stabilizing agent. [more]
what‑it‑does preservative | perfuming | solvent | viscosity controlling
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically. No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. [more]
what‑it‑does moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does emollient | perfuming | solvent
A hydrocarbon-based emollient that can come in different viscosities from silky-light to luxurious, rich. It forms a non-occlusive film on the surface of the skin. [more]
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores and it's a potent anti-inflammatory agent. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does soothing
Menthol needs no introduction: it's the thing that causes the cooling sensation so well-known both from cosmetic products as well as a bunch of other things like chocolate, chewing gum, toothpaste or cigarette. It's a natural compound that comes from the essential oil of Mentha species (peppermint oil contains 40-50% menthol) and it gives them their typical minty smell a [more]
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]
what‑it‑does emulsifying | surfactant/cleansing
what‑it‑does skin-identical ingredient | moisturizer/humectant
Amino acids are important natural moisturizing factors (NMFs), that can be found naturally in the skin where they help the epidermis (upper layer of the skin) to stay nice and hydrated. Amino acids are also the building blocks of proteins, such as collagen, so when you thoroughly chop up a big collagen molecule, you end up with an amino acid mixture, like this guy we are writing about. [more]
what‑it‑does antimicrobial/antibacterial | solvent | viscosity controlling
Simple alcohol that's a great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent, and antimicrobial. In large amount can be very drying. [more]
what‑it‑does moisturizer/humectant
A chemically chopped up version of wheat protein with moisturizing and film-forming properties. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does viscosity controlling
irritancy, com. 0, 0
These three letters stand for Poly Vinyl Pyrollidone, a big molecule created from repeated units of Vinyl Pyrrolidone, aka VP. Its main thing is being an important film former. [more]
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does emulsifying | surfactant/cleansing
what‑it‑does preservative
A preservative that works mainly against fungi and has only milder effect against bacteria. Popular in natural products.  [more]
what‑it‑does emollient | emulsifying
It's quite the multi-tasker: an emollient and water-binding ingredient but also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.  [more]
what‑it‑does viscosity controlling
irritancy, com. 0, 1
A handy white powder that magically converts a liquid into a nice gel formula. [more]
what‑it‑does perfuming
It’s a common fragrance ingredient that has a light floral smell.  It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does perfuming
A common fragrance ingredient that smells like jasmine. It is one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. [more]
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0, 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
what‑it‑does perfuming | solvent
A super common fragrance ingredient found naturally in many plants including citrus peel oils, rosemary or lavender. It autoxidizes on air exposure and counts as a common skin sensitizer. [more]
what‑it‑does preservative
A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast. [more]
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]