Laser Whitening Program
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ISOI Laser Whitening ProgramIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Simply alcohol refers to ethanol and it's a pretty controversial ingredient. It has many instant benefits: it's a great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial. No wonder it's popular in toners and oily skin formulas.
The downside is that it can be very drying if it's in the first few ingredients on an ingredient list.
Some experts even think that regular exposure to alcohol damages skin barrier and causes inflammation though it's a debated opinion. If you wanna know more, we wrote a more detailed explanation about what's the deal with alcohol in skincare products at alcohol denat. (it's also alcohol, but with some additives to make sure no one drinks it).
A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance. It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability.
It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler.
A pretty well-known and often used ingredient with the magic ability to fade brown spots. It's used traditionally in Japan and can be found naturally in a couple of plants, including the leaves of pear trees, wheat and bearberry.
Arbutin seems to work its magic and hinder the pigmentation process at the second step of it. An enzyme called tyrosinase is needed to create melanin (the pigment that causes the brown spots) and while several other skin lightening agents work to inhibit the synthesis of tyrosinase itself (like vitamin C or licorice), arbutin lets tyrosinase be and rather hinders the melanin-forming activity of the enzyme. (So it might be a good idea to combine arbutin with some direct tyrosinase inhibitors for more skin lightening effect.)
All in all, arbutin is one of the better-known skin brightening agents, that's probably worth a try if pigmentation is an issue for you.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
The flower water coming from the flowers of the Damask Rose. In general, flower waters (also called hydrosols) are diluted versions of essential oils coming from the same plant. They contain the same components but in much-reduced concentrations.
Similar to its big sister, rose oil, rose water also has a lovely, relaxing scent. It contains some antioxidant and antimicrobial compounds, as well as some fragrant components.
If your skin is super sensitive, it is a good idea to choose products without fragrant floral waters.
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The extract coming from the bark of the White Willow, a big (25 m/80 ft.) tree that likes to live on riverbanks. It's famous for containing anti-inflammatory natural salicylates (this powder, for example, is standardized to contain 53-65%), a close chemical relative to famous exfoliant salicylic acid.
Thanks to its salicin content, willow bark is often touted as a natural alternative to salicylic acid, though it's quite questionable how effective it is as a chemical exfoliant in the tiny amounts used in cosmetics. Apart from soothing salicin, it also contains flavonoids and phenolic acids that give willow bark tonic, astringent, and antiseptic properties.
Centella Asiatica - or sometimes also called Gotu Kola or Cica - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.
Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).
One of the biological activities of the centellosides is to be able to stimulate GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells), and especially hyaluronic acid synthesis in our skin. This is probably one of the reasons why Centella Asiatica Extract has nice skin moisturizing properties that was confirmed by a 25 people, four weeks study along with Centella's anti-inflammatory effects.
Madecassoside can also help in burn wound healing through increasing antioxidant activity and enhancing collagen synthesis. Asiaticoside was shown to increase antioxidant levels on rats skin when applied at 0.2%.
Centella Asiatica also often shows up in products that try to treat cellulite or striae. Of course, it cannot make a miracle but it might have some effect via regulating microcirculation and normalizing the metabolism in the cells of connective tissues.
Bottom line: Gotu Kola is a great plant ingredient with proven wound healing, anti-inflammatory, and antioxidant properties. Nice to spot on any ingredient list.
A traditional Chinese herbal medicine loaded with potent antioxidant and anti-inflammatory flavonoids such as baicalin, baicalein, and wogonin.
If that would not be enough, Skullcap Root is also claimed to have antimicrobial and antifungal properties (also against P.acnes and Malassezia furfur) as well as some skin-brightening activity. A multi-functional skin-goodie.
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You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. It's sweet and yellow and not only used for licorice all sorts but it's also a skincare superstar thanks to two magic properties:
Nr. 1 magic property is that it has skin-lightening or to say it another way depigmenting properties. The most active part is called glabridin. The topical application (meaning when you put it on your face) of 0.5% glabridin was shown to inhibit UVB caused pigmentation of guinea pigs. Another study even suggested that licorice is more effective than the gold standard skin-lightening agent hydroquinone. All in all, licorice is considered to be one of the safest skin lightening agents with the fewest side effects.
There is just one catch regarding glabridin and licorice: the amount of glabridin in commercial licorice extracts can vary a lot. We have seen extracts with only 4% glabridin as well as 40% glabridin. The latter one is a very-very expensive ingredient, so if you are after the depigmenting properties try to choose a product that boasts its high-quality licorice extract.
Nr. 2 magic property is that licorice is a potent anti-inflammatory. Glabridin has also some soothing properties but the main active anti-inflammatory component is glycyrrhizin. It’s used to treat several skin diseases that are connected to inflammation including atopic dermatitis, rosacea or eczema.
Oh, and one more thing: glabridin seems to be also an antioxidant, which is just one more reason to be happy about licorice root extract on an ingredient list.
Bottom line: Licorice is a great skincare ingredient with significant depigmenting, anti-inflammatory and even some antioxidant properties. Be happy if it's on the ingredient list. :)
The oil coming from the pulp of the sea buckthorn berry. It has a pretty unique fatty acid composition: 65% is a combination of the rare Omega-7, aka palmitoleic acid and the more common palmitic acid. Fatty acids give the oil nice moisturizing and skin-protecting abilities.
But that's not all the goodness of sea buckthorn oil. It contains antioxidant superstar, Vitamin E (in multiple forms), antioxidant (and orange color giving) pigments beta-carotene and lycopene, as well as skin-soothing and replenishing beta-sitosterol.
Btw, used undiluted, it will make your skin orange.
All in all, a goodie emollient plant oil.
We are big fans of all kinds of roses as ornamental plants but when it comes to skincare, it is a mixed bag. Before we list out the good and the not so good, here is an interesting thing.
The oil content in rose is very, very low so distilling rose essential oil requires huge amounts of rose flowers. It has such a wonderful scent that there are no comparable synthetic alternatives. You can probably guess that this means rose essential oil is expensive.... very very expensive.
So the good things: thanks to its wonderful scent the high-end perfume industry loves rose oil. Also, we (humans :)) love rose oil. We love its scent so much that it can heal headaches, depression, stress, and even grief.
Rose oil contains more than 95 compounds, among them flavonoids, anthocyanins, vitamin C, and quercetin that are all known for their medicinal properties and great antioxidant effects. Similar to many other essential oils, it has antimicrobial properties too.
Now, the not-so-good thing? Out of the 95 compounds, the major ones are citronellol and geraniol, fragrant components that might irritate sensitive skin.
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When you hear the word Soy, you probably associate it with soy sauce or tofu, not skincare. But as it turns out, the soybean has a bunch of useful active components and soybean extract is an interesting cosmetic ingredient with a wide range of possible effects.
Its main active components are antioxidant phenolic acids and flavonoids as well as small and large soy proteins. The large proteins give soybean extract nice skin smoothing and softening properties, while the small proteins (soybean trypsin inhibitor (STI) and Bowman-Birk inhibitor (BBI)) are thought to inhibit skin pigmentation and delay hair regrowth.
Regarding skin pigmentation, the soybean extract works by hindering melanosome transfer, meaning it blocks the melanin pigment from traveling up to the surface of the skin and becoming visible there. This is useful for most pigmentation situations but, if you have melasma, soy is not for you as melasma is estrogen-mediated and soy is a well-known phytoestrogen.
The most famous and bioactive flavonoids in soybeans are the isoflavones called genistein and diadzein that have potent antioxidant and anti-inflammatory properties. Genistein is also proven to inhibit UV induced redness in human skin. These isoflavones are also the ones that make soy a phytoestrogen, meaning they have a (weak) estrogenic effect. Topical estrogen is known to decrease skin thinning and collagen loss and soy might be able to do the same, especially during and after menopause when natural estrogen levels run low.
There is also some promising, but as yet not in-vivo (done on real people), research that soybean extract can stimulate both elastin and collagen synthesis and thus lead to healthier, younger-looking skin.
Overall, soybean extract is a promising and multi-functional active, a nice addition to most ingredient lists.
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- Green tea is one of the most researched natural ingredients
- The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
- There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
- Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
- Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis
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Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives.
The extract coming from the popular garden plant Calendula or Marigold. According to manufacturer info, it's used for many centuries for its exceptional healing powers and is particularly remarkable in the treatment of wounds. It contains flavonoids that give the plant anti-inflammatory and antioxidant properties.
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We don't have description for this ingredient yet.
Citronellol is a very common fragrance ingredient with a nice rose-like odor. In the UK, it’s actually the third most often listed perfume on the ingredient lists.
It can be naturally found in geranium oil (about 30%) or rose oil (about 25%).
As with all fragrance ingredients, citronellol can also cause allergic contact dermatitis and should be avoided if you have perfume allergy. In a 2001 worldwide study with 178 people with known sensitization to fragrances citronellol tested positive in 5.6% of the cases.
There is no known anti-aging or positive skin benefits of the ingredient. It’s in our products to make it smell nice.
Geraniol is a common fragrance ingredient. It smells like rose and can be found in rose oil or in small quantities in geranium, lemon and many other essential oils.
Just like other similar fragrance ingredients (like linalool and limonene) geraniol also oxidises on air exposure and becomes allergenic. Best to avoid if you have sensitive skin.
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| what‑it‑does | solvent |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | antimicrobial/antibacterial | solvent | viscosity controlling |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | antioxidant | skin brightening |
| what‑it‑does | viscosity controlling |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | perfuming |
| what‑it‑does | soothing |
| what‑it‑does | soothing |
| what‑it‑does | soothing | antioxidant | moisturizer/humectant |
| what‑it‑does | soothing | antioxidant | antimicrobial/antibacterial | moisturizer/humectant |
| what‑it‑does | soothing | skin brightening |
| what‑it‑does | antioxidant | emollient |
| what‑it‑does | antioxidant | perfuming | antimicrobial/antibacterial |
| what‑it‑does | perfuming |
| what‑it‑does | antioxidant | skin brightening | soothing | emollient |
| what‑it‑does | soothing |
| what‑it‑does | antioxidant | soothing |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | solvent |
| what‑it‑does | soothing | antioxidant | perfuming |
| what‑it‑does | antimicrobial/antibacterial |
| what‑it‑does | antimicrobial/antibacterial |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |