Cicabiafine Anti-irritation Moisturizing Body Cream
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Biafine Cicabiafine Anti-irritation Moisturizing Body CreamIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
The famous or maybe rather infamous mineral oil. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. It is a very controversial ingredient with pros and cons and plenty of myths around it. So let us see them:
The pros of mineral oil
Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert.
It is a great emollient and moisturizer working mainly by occlusivity. Occlusivity is one of the basic mechanisms of how moisturizers work and it means that mineral oil sits on top of the skin and hinders so-called trans-epidermal water loss, i.e water evaporating out of your skin. When compared to heavy-duty plant oil, extra virgin coconut oil, the two of them were equally efficient and safe as moisturizers in treating xerosis, a skin condition connected to very dry skin.
The other thing that mineral oil is really good at is being non-irritating to the skin. The chemical composition of plant oils is more complex with many more possible allergens or irritating components, while mineral oil is simple, pure and sensitivity to it is extremely rare. If you check out the classic French pharmacy brands and their moisturizers for the most sensitive, allergy prone skin, they usually contain mineral oil. This is no coincidence.
The cons of mineral oil
The pros of mineral oil can be interpreted as cons if we look at them from another perspective. Not penetrating the skin but mostly just sitting on top of it and not containing biologically active components, like nice fatty acids and vitamins mean that mineral oil does not "nourish" the skin in the way plant oils do. Mineral oil does not give the skin any extra goodness, it is simply a non-irritating moisturizer working mainly by occlusivity.
The myths around mineral oil
Badmouthing mineral oil is a favorite sport of many, it is a cheap material and being connected to petrolatum makes it fairly easy to demonize.
While it is true that industrial grade mineral oil contains carcinogenic components (so-called polycyclic compounds), these are completely removed from cosmetic and food grade mineral oil and there is no scientific data showing that the pure, cosmetic grade version is carcinogenic.
What is more, in terms of the general health effects of mineral oils used in cosmetics, a 2017 study reviewed the data on their skin penetration and concluded that "the cosmetic use of mineral oils and waxes does not present a risk to consumers due to a lack of systemic exposure."
Another super common myth surrounding mineral oil is that it is comedogenic. A 2005 study titled "Is mineral oil comedogenic?" examined this very question and guess what happened? The study concluded that "based on the animal and human data reported, along with the AAD recommendation, it would appear reasonable to conclude that mineral oil is noncomedogenic in humans."
Overall, we feel that the scaremongering around mineral oil is not justified. For dry and super-sensitive skin types it is a great option. However, if you do not like its origin or its heavy feeling or anything else about it, avoiding it has never been easier. Mineral oil has such a bad reputation nowadays that cosmetic companies hardly dare to use it anymore.
Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.
But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat.
The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.
The unique thing about petrolatum is that it is the most effective occlusive agent known today. While the occlusivity of mineral oil is in the same league as the occlusivity of plant oils, petrolatum is in a league of its own. It sits on top of the skin and hinders so-called transepidermal water loss (TEWL) like nothing else.
This comes in handy healing cracked lips or severely dry skin patches, though overdoing it (i.e. reducing TEWL by more than 40%) is not good as it can create a nice moist place for fungi and bacteria to grow.
As for petrolatum and safety, we can write here pretty much the exact same thing as we have written at mineral oil. There is no evidence whatsoever that cosmetic, USP grade petrolatum is carcinogenic. It also does not absorb into the skin but sits on top of it and that in itself greatly minimises health risks. It also has a long history of safe use, as it was first used as a skincare product more than 100 years ago, in 1872 to be precise.
It is also non-comedogenic, though its pure form is very heavy and greasy so combination and oily skin types might want to avoid it anyway.
Overall, it is the gold-standard occlusive agent known today and a tub of Vaseline comes in handy in any household to heal cracked lips or other severely dry skin patches.
We don't have description for this ingredient yet.
A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together.
It's often paired with glyceryl stearate - the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
A handy multi-tasker, white to light yellowish oil-loving wax that works very well in oil-in-water emulsions. It makes your skin feel nice and smooth (emollient), stabilizes oil-water mixes and gives body to them.
Oh, and one more thing: it's a so-called fatty alcohol - the good, emollient type of alcohol that is non-drying and non-irritating. It is often mixed with fellow fatty alcohol, Cetyl Alcohol, and the mixture is called Cetearyl Alcohol in the ingredient list.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
When you hear oatmeal, you probably think of breakfast, but the finely ground version of whole oat kernels, aka colloidal oatmeal, can do good things for your skin, especially if it's dry, itchy or prone to skin-rashes or eczema.
Oat is loaded with compounds good for the body, inside or outside, such as soothing agent beta-glucan (5%), lipids (3-11%) including barrier repairing omega-3 and 6 fatty acids or phenolic antioxidant and anti-inflammatory agents (avenanthramides).
The soothing, antioxidant and skin-protecting abilities of oat are so well-established that it is an active natural ingredient covered by the FDA OTC Skin Protectant monograph in the US, meaning that colloidal oatmeal can be claimed as an active ingredient on the INCI list and Aveeno is a mass-market brand built around oat-containing products.
If your skin is dry, irritated, inflamed or eczema-prone, colloidal oatmeal is something to try.
We don't have description for this ingredient yet.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
We don't have description for this ingredient yet.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A vegetable wax coming from the leaves of the North Mexican candelilla shrubs (Euphorbia cerifera and Euphorbia antisyphilitica). Similar to other waxes, it is used to stabilize products and give body to them, or to keep stick type formulas solid. It has a melting point around 70C and has high gloss making it a good choice for lip products.
A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.
A fatty acid that can be found naturally in the skin. In fact, it's the most common saturated fatty acid found in animals and plants.
As for skincare, it can make the skin feel nice and smooth in moisturizers (emollient) or it can act as a foam building cleansing agent in cleansers. It's also a very popular ingredient in shaving foams.
A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).
A superabsorbent polymer (big molecule from repeated subunits) that has crazy water binding abilities. Sometimes its referred to as "waterlock" and can absorb 100 to 1000 times its mass in water.
As for its use in cosmetic products, it is a handy multi-tasker that thickens up water-based formulas and also has some emulsifying and emulsion stabilizing properties.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
A form of skincare superstar, vitamin C. Even though we are massive vitamin C fans, Ascorbyl Palmitate (AP) is our least favorite. (Btw, if you do not know what the big deal with vitamin C is then you are missing out. You must go and read our geeky details about it.)
So, AP is one of the attempts by the cosmetics industry to solve the stability issues with vitamin C while preserving its benefits, but it seems to fall short on several things.
What's the problem?
Firstly, it's stability is only similar to that of pure ascorbic acid (AA), which means it is not really stable. A great study in the Journal of Cosmetic Dermatology compared a bunch of vitamin C derivatives and this derivative was the only one where the study said in terms of stability that it's "similar to AA". Not really that good.
Second, a study that examined the skin absorption of vitamin C found that ascorbyl palmitate did not increase the skin levels of AA. This does not mean that ascorbyl palmitate cannot penetrate the skin (because it can, it's oil soluble and the skin likes to absorb oil soluble things) but this means that it's questionable if ascorbyl palmitate can be converted into pure Vit C in the skin. Even if it can be converted, the palmitate part of the molecule is more than the half of it, so the efficacy will not be good and we have never seen a serum that contains a decent (and proudly disclosed) amount of AP. We are highly skeptical what effect a tiny amount of AP has in a formula.
Third, another study that wanted to examine the antioxidant properties of AP was surprised to find that even though AP does have nice antioxidant properties; following UVB radiation (the same one that comes from the sun) it also promotes lipid peroxidation and cytotoxicity. It was only an in-vitro study meaning that it was done on cell cultures and not on real people, but still, this also does not support the use of AP too much.
The only good thing we can write about Ascorbyl Palmitate is that there is an in-vitro (made in the lab, not on real people) study showing that it might be able to boost collagen production.
Regarding the skin-brightening properties of pure vitamin C, this is another magic property AP does not have, or at least there is no data, not even in-vitro, about it.
Overall, Ascorbyl Palmitate is our least favorite vitamin C derivative. It is there in lots of products in tiny amounts (honestly, we do not really understand why), however, we do not know about any vitamin C serum featuring AP in high amounts. That is probably no coincidence. If you are into vitamin C, you can take a look at more promising derivatives here.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4).
But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.
BTW, it’s also a food preservative and even has an E number, E202.
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| what‑it‑does | solvent |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | solvent |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| what‑it‑does | surfactant/cleansing | emulsifying |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 2, 2 |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant | soothing | emollient | abrasive/scrub |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | preservative |
| what‑it‑does | emollient |
| irritancy, com. | 0, 3 |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | skin-identical ingredient | emollient | emulsifying |
| irritancy, com. | 0, 2 |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 0, 2-3 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | chelating |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 2 |
| what‑it‑does | preservative |
| what‑it‑does | preservative |