BeautyBioscience R45 The Reversal 3-Phase Skin Transforming Treatment
BeautyBioscience

R45 The Reversal 3-Phase Skin Transforming Treatment

A patented 3-phase treatment with increasing concentrations of key ingredients that push skin's performance to break through anti-aging plateaus, resulting in a visibly younger, firmer complexion, consisting of proprietary Regeneration [more] [more] Complex and Growth Factor Stimulant (GFS) Serum, housed in separate airless containers to remain stable at maximum concentrations and combine during application to work synergistically in the deepest layers of the skin. [less]
Uploaded by: incieolder on 15/09/2018

Ingredients overview

(Regeneration Complex:) Water
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Cocoglycerides
what‑it‑does emollient | emulsifying
,
Safflower Acids, Tocopheryl Acetate
what‑it‑does antioxidant
irritancy, com. 0 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
,
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
what‑it‑does viscosity controlling
Common helper ingredient that stabilizes emulsions and helps to thicken up products. It's also a film-former. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Lysolecithin
what‑it‑does emulsifying
,
Retinol
what‑it‑does cell-communicating ingredient
Vitamin A - the most proven anti-aging ingredient available OTC that can smooth wrinkles and make skin firmer. It might also be useful for acne-prone skin as it normalizes keratinization. [more]
,
Glyceryl Diretinoate, [more] Glyceryl 10 Laurate
what‑it‑does surfactant/cleansing | emulsifying
A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. Also used as a co-emulsifier.
,
Retinyl Palmitate
what‑it‑does cell-communicating ingredient
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
,
Citric Acid
what‑it‑does exfoliant | buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
,
Bht
what‑it‑does antioxidant | preservative
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.There is some controversy around BHT. [more]
,
Acetyl Carboxymethyl Cocoyl Glycine
what‑it‑does chelating
,
Safflower Glyceride
what‑it‑does emollient | emulsifying | surfactant/cleansing
,
Tocopheryl Acetate
what‑it‑does antioxidant
irritancy, com. 0 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
(Gfs Serum:) Water
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Cyclopentasiloxane
what‑it‑does emollient | solvent
It's a super commonly used water-thin volatile silicone that gives skin and hair a silky, smooth feel.  [more]
,
Pentylene Glycol
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
,
Peg-12 Dimethicone Crosspolymer
what‑it‑does emulsifying | viscosity controlling
,
Dimethicone Crosspolymer
what‑it‑does viscosity controlling
A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent. [more]
,
Dimethicone/Vinyl Dimethicone Crosspolymer
what‑it‑does viscosity controlling
A white, elastomeric silicone powder that gives a nice silky and powdery feel to the products. [more]
,
Sodium Polyacrylate
what‑it‑does viscosity controlling
A big polymer (a molecule from repeated subunits) with crazy water binding abilities. Used as a thickening and emulsion stabilizing agent. [more]
,
Dimethicone
what‑it‑does emollient
irritancy, com. 0 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
,
Peg/Ppg-18 / 18 Dimethicone
what‑it‑does emulsifying
A silicone emulsifier that helps to create water in silicone emulsions. 
,
Dimethiconol
what‑it‑does emollient | moisturizer/humectant
A thick, high molecular weight silicone that is usually diluted in a lighter silicone fluid. The dimethiconol containing silicone blends leave a silky smooth, non-greasy film on the skin. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Camellia Sinensis Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
,
Disodium Edta Copper
what‑it‑does chelating
,
Myristoyl Pentapeptide 17
what‑it‑does cell-communicating ingredient
A five amino acid peptide (Lys-Leu-Ala-Lys-Lys) attached to the oil-soluble fatty acid, myristic acid for better bioavailability. It is known to significantly stimulate keratin genes, i. [more]
,
Hydroxyphenyl Propamidobenzoic Acid
what‑it‑does soothing
An anti-irritant and anti-itch molecule that copies the active ingredient in the well-known soothing plant, oat.  [more]
,
Bisabolol
what‑it‑does soothing
One of the active parts of Chamomile that is used in skincare as a nice anti-inflammatory and soothing ingredient. [more]
,
Zingiber Officinale (Ginger) Root Extract
what‑it‑does antioxidant | soothing
Ginger extract that has antioxidant and soothing properties. It is also known to increase blood circulation and thus have a toning effect. [more]
,
Polysorbate 60
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
[less]
REGENERATION COMPLEX: WATER, COCOGLYCERIDES, SAFFLOWER ACIDS, TOCOPHERYL ACETATE, ACRYLATES/C 10-30 ALKYL ACRYLATE CROSSPOLYMER, SODIUM HYALURONATE, LYSOLECITHIN, RETINOL, GLYCERYL DIRETINOATE, GLYCERYL 10 LAURATE, RETINYL PALMITATE, CITRIC ACID, BHT, ACETYL CARBOXYMETHYL COCOYL GLYCINATE, SAFFLOWER GLYCERIDES, TOCOPHERYL ACETATE, CAPRYLYL GLYCOL, PHENOXYETHANOL. GFS SERUM: WATER, GLYCERIN, BUTYLENE GLYCOL, CYCLOPENTASILOXANE, PENTYLENE GLYCOL, PEG-12 DIMETHICONE CROSSPOLYMER, DIMETHICONE CROSSPOLYMER, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, SODIUM POLYACRYLATE, DIMETHICONE, PEG/PPG-18 / 18 DIMETHICONE, DIMETHICONOL, SODIUM HYALURONATE, CAMELLIA SINENSIS EXTRACT, DISODIUM EDTA COPPER, MYRISTOYL PENTAPEPTIDE 17, HYDROXYPHENYL PROPAMIDOBENZOIC ACID, BISABOLOL, ZINGIBER OFFICINALE (GINGER) ROOT EXTRACT, POLYSORBATE 60, CAPRYLYL GLYCOL, PHENOXYETHANOL.

Highlights

Key Ingredients

Antioxidant: Tocopheryl Acetate
what‑it‑does antioxidant
irritancy, com. 0 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
,
Tocopheryl Acetate
what‑it‑does antioxidant
irritancy, com. 0 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
,
Camellia Sinensis Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
,
Zingiber Officinale (Ginger) Root Extract
what‑it‑does antioxidant | soothing
Ginger extract that has antioxidant and soothing properties. It is also known to increase blood circulation and thus have a toning effect. [more]
Cell-communicating ingredient: Retinol
what‑it‑does cell-communicating ingredient
Vitamin A - the most proven anti-aging ingredient available OTC that can smooth wrinkles and make skin firmer. It might also be useful for acne-prone skin as it normalizes keratinization. [more]
,
Retinyl Palmitate
what‑it‑does cell-communicating ingredient
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
,
Myristoyl Pentapeptide 17
what‑it‑does cell-communicating ingredient
A five amino acid peptide (Lys-Leu-Ala-Lys-Lys) attached to the oil-soluble fatty acid, myristic acid for better bioavailability. It is known to significantly stimulate keratin genes, i. [more]
Skin-identical ingredient: Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
Soothing: Camellia Sinensis Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
,
Hydroxyphenyl Propamidobenzoic Acid
what‑it‑does soothing
An anti-irritant and anti-itch molecule that copies the active ingredient in the well-known soothing plant, oat.  [more]
,
Bisabolol
what‑it‑does soothing
One of the active parts of Chamomile that is used in skincare as a nice anti-inflammatory and soothing ingredient. [more]
,
Zingiber Officinale (Ginger) Root Extract
what‑it‑does antioxidant | soothing
Ginger extract that has antioxidant and soothing properties. It is also known to increase blood circulation and thus have a toning effect. [more]

Show all ingredients by function

Other Ingredients

Antimicrobial/antibacterial: Camellia Sinensis Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
Antioxidant: Bht
what‑it‑does antioxidant | preservative
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.There is some controversy around BHT. [more]
Buffering: Citric Acid
what‑it‑does exfoliant | buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
Emollient: Cocoglycerides
what‑it‑does emollient | emulsifying
,
Safflower Glyceride
what‑it‑does emollient | emulsifying | surfactant/cleansing
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
,
Cyclopentasiloxane
what‑it‑does emollient | solvent
It's a super commonly used water-thin volatile silicone that gives skin and hair a silky, smooth feel.  [more]
,
Dimethicone
what‑it‑does emollient
irritancy, com. 0 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
,
Dimethiconol
what‑it‑does emollient | moisturizer/humectant
A thick, high molecular weight silicone that is usually diluted in a lighter silicone fluid. The dimethiconol containing silicone blends leave a silky smooth, non-greasy film on the skin. [more]
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
Emulsifying: Cocoglycerides
what‑it‑does emollient | emulsifying
,
Lysolecithin
what‑it‑does emulsifying
,
Glyceryl 10 Laurate
what‑it‑does surfactant/cleansing | emulsifying
A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. Also used as a co-emulsifier.
,
Safflower Glyceride
what‑it‑does emollient | emulsifying | surfactant/cleansing
,
Peg-12 Dimethicone Crosspolymer
what‑it‑does emulsifying | viscosity controlling
,
Peg/Ppg-18 / 18 Dimethicone
what‑it‑does emulsifying
A silicone emulsifier that helps to create water in silicone emulsions. 
,
Polysorbate 60
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
Exfoliant: Citric Acid
what‑it‑does exfoliant | buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
Moisturizer/humectant: Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
,
Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Pentylene Glycol
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
,
Dimethiconol
what‑it‑does emollient | moisturizer/humectant
A thick, high molecular weight silicone that is usually diluted in a lighter silicone fluid. The dimethiconol containing silicone blends leave a silky smooth, non-greasy film on the skin. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
Preservative: Bht
what‑it‑does antioxidant | preservative
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.There is some controversy around BHT. [more]
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
Solvent: (Regeneration Complex:) Water
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
(Gfs Serum:) Water
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Cyclopentasiloxane
what‑it‑does emollient | solvent
It's a super commonly used water-thin volatile silicone that gives skin and hair a silky, smooth feel.  [more]
,
Pentylene Glycol
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
Surfactant/cleansing: Glyceryl 10 Laurate
what‑it‑does surfactant/cleansing | emulsifying
A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. Also used as a co-emulsifier.
,
Safflower Glyceride
what‑it‑does emollient | emulsifying | surfactant/cleansing
,
Polysorbate 60
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
Viscosity controlling: Acrylates/C10-30 Alkyl Acrylate Crosspolymer
what‑it‑does viscosity controlling
Common helper ingredient that stabilizes emulsions and helps to thicken up products. It's also a film-former. [more]
,
Peg-12 Dimethicone Crosspolymer
what‑it‑does emulsifying | viscosity controlling
,
Dimethicone Crosspolymer
what‑it‑does viscosity controlling
A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent. [more]
,
Dimethicone/Vinyl Dimethicone Crosspolymer
what‑it‑does viscosity controlling
A white, elastomeric silicone powder that gives a nice silky and powdery feel to the products. [more]
,
Sodium Polyacrylate
what‑it‑does viscosity controlling
A big polymer (a molecule from repeated subunits) with crazy water binding abilities. Used as a thickening and emulsion stabilizing agent. [more]

Skim through

Ingredient name what-it-does irr., com. ID-Rating
(Regeneration Complex:) Water solvent
Cocoglycerides emollient, emulsifying
Safflower Acids
Tocopheryl Acetate antioxidant 0, 0
Acrylates/C10-30 Alkyl Acrylate Crosspolymer viscosity controlling
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Lysolecithin emulsifying
Retinol cell-communicating ingredient superstar
Glyceryl Diretinoate
Glyceryl 10 Laurate surfactant/​cleansing, emulsifying
Retinyl Palmitate cell-communicating ingredient
Citric Acid exfoliant, buffering goodie
Bht antioxidant, preservative
Acetyl Carboxymethyl Cocoyl Glycine chelating
Safflower Glyceride emollient, emulsifying, surfactant/​cleansing
Tocopheryl Acetate antioxidant 0, 0
Caprylyl Glycol moisturizer/​humectant, emollient
Phenoxyethanol preservative
(Gfs Serum:) Water solvent
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Cyclopentasiloxane emollient, solvent
Pentylene Glycol solvent, moisturizer/​humectant
Peg-12 Dimethicone Crosspolymer emulsifying, viscosity controlling
Dimethicone Crosspolymer viscosity controlling
Dimethicone/Vinyl Dimethicone Crosspolymer viscosity controlling
Sodium Polyacrylate viscosity controlling
Dimethicone emollient 0, 1
Peg/Ppg-18 / 18 Dimethicone emulsifying
Dimethiconol emollient, moisturizer/​humectant
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Camellia Sinensis Extract antioxidant, soothing, antimicrobial/​antibacterial superstar
Disodium Edta Copper chelating
Myristoyl Pentapeptide 17 cell-communicating ingredient goodie
Hydroxyphenyl Propamidobenzoic Acid soothing goodie
Bisabolol soothing goodie
Zingiber Officinale (Ginger) Root Extract antioxidant, soothing goodie
Polysorbate 60 emulsifying, surfactant/​cleansing
Caprylyl Glycol moisturizer/​humectant, emollient
Phenoxyethanol preservative

Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Expand to read more

Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

What-it-does: emollient, emulsifying

We don't have description for this ingredient yet.

This ingredient name is not according to the INCI-standard. :( What, why?!

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

It’s a super commonly used, not-very-friendly-named helper ingredient that can help to stabilize emulsions (so that the water and the oil components stay nicely together). It can also be a thickener that helps to create nice gel formulas as well as a film-former. 

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

Expand to read more

In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

What-it-does: emulsifying

We don't have description for this ingredient yet.

Retinol - superstar
Also-called: Vitamin A, Form of Retinoids | What-it-does: cell-communicating ingredient
  • Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
  • Retinol is not itself active, it has to be converted in the skin to retinoic acid to actually do something
  • Once converted it theoretically has the same effect as all-trans-retinoic acid, aka tretinoin
  • A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
  • It makes skin less wrinkled, smoother, firmer and tighter
  • It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
  • Possible side effects and irritation are also much less than with retinoic acid
  • Do not use whilst pregnant
Read all the geeky details about Retinol here >>

We don't have description for this ingredient yet.

A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. It's also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products. 

Also-called: Form of Retinoids | What-it-does: cell-communicating ingredient

It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the queen being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince William, two steps away from the throne. Retinyl palmitate will be then little Prince George, quite far (3 steps) away from the throne. 

By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:

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retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid

As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective

What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD,  director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre. 

Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here.  It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA. 

We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!

Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.

Citric Acid - goodie
What-it-does: exfoliant, buffering

Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA. 

So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh. 

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There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin. 

But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation. 

Bht
Also-called: Butylated Hydroxy Toluene | What-it-does: antioxidant, preservative

It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.

There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.

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As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%),  it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.

What-it-does: chelating

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

Glycerin - goodie
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • Super common, used for more than 50 years
  • Not only a simple moisturizer but plays an important role in keeping the stuff between our skin cells healthy
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

What-it-does: emollient, solvent

A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel

It's often combined with the non-volatile (aka stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

We don't have description for this ingredient yet.

A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent.

What-it-does: viscosity controlling

A white, elastomeric silicone powder that gives a nice silky and powdery feel to the products. It also has some oil and sebum absorption capabilities. 

A superabsorbent polymer (big molecule from repeated subunits) that has crazy water binding abilities. Sometimes its referred to as "waterlock" and can absorb 100 to 1000 times its mass in water. 

As for its use in cosmetic products, it is a handy multi-tasker that thickens up water-based formulas and also has some emulsifying and emulsion stabilizing properties. 

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the cheapest and most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier. Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

What-it-does: emulsifying

A silicone emulsifier that helps to create water in silicone emulsions. 

A thick, high molecular weight silicone that is usually diluted in another, lighter silicone fluid (like dimethicone or cyclopentasiloxane). The dimethiconol containing silicone blends leave a silky smooth, non-greasy film on the skin.

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

Also-called: Green Tea | What-it-does: antioxidant, soothing, antimicrobial/antibacterial
  • Green tea is one of the most researched natural ingredients
  • The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
  • There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
  • Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
  • Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis
Read all the geeky details about Camellia Sinensis Leaf Extract here >>

What-it-does: chelating, astringent

We don't have description for this ingredient yet.

Also-called: SymPeptide 226 | What-it-does: cell-communicating ingredient

A five amino acid peptide (Lys-Leu-Ala-Lys-Lys) attached to the oil-soluble fatty acid, myristic acid for better bioavailability. It is known to significantly stimulate keratin genes, i. e. it can convince the cells to produce more keratin, the super important structural protein in hair, nails and the outermost layer of the skin.

Most often you will meet Myristoyl Pentapeptide-17 combined with Myristoyl Hexapeptide-16 in eyelash growth products, as the two together can visibly increase eyelash length after two weeks. 

Also-called: SymCalmin | What-it-does: soothing

An anti-irritant and anti-itch molecule that copies the active ingredient (Avenanthramides) in the well-known soothing plant, oat. 

According to the manufacturer's clinical study (double-blind, 40 people, 4 weeks long), 2% SymCalmin (the trade name of our diluted - 5% - molecule) reduced itchiness significantly by 65% and it also reduced redness by 50%. 

Bisabolol - goodie
Also-called: Alpha-Bisabolol | What-it-does: soothing

It's one of the active parts of Chamomile that contains about 30% of bisabolol. It's a clear oily fluid that is used in skincare as a nice anti-inflammatory and soothing ingredient. 

Also-called: Ginger Root Extract | What-it-does: antioxidant, soothing

The extract coming from ginger, the lovely spice that we all know from the kitchen. It is also a medicinal plant used both in Chinese and Ayurvedic medicine for pretty much everything you can imagine (muscular pain, sore throat, nausea, fever or cramps,  just to give a few examples).

As for ginger and skincare, the root extract contains the biologically active component called gingerol that has potent antioxidant and anti-inflammatory properties. Combined with Bisabololthe duo works synergistically to sooth the skin and take down redness. 

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Other than that, ginger also contains moisturizing polysaccharides, amino acids, and sugars, and it is also quite well known to increase blood circulation and have a toning effect.

Last but not least, Ginger also has some volatile, essential oil compounds (1-3%). Those are mostly present in ginger oil, but small amounts might be in the extract as well (around 0.5% based on manufacturer info). 

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

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