The Ordinary Matrixyl 10% + Ha
The Ordinary

Matrixyl 10% + Ha

This highly-effective composition has been shown to reduce the look of static and dynamic wrinkles. This formula contains two generations of Matrixyl, Matrixyl 3000 and Matrixyl Synthe'6, at a combined concentration of 10% by weight in a specialized Hyaluronic Acid delivery system.
Uploaded by: suecake on 13/10/2016

Ingredients overview

Aqua (Water)
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
,
Palmitoyl Tetrapeptide-7
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
,
Palmitoyl Tripeptide-38
what‑it‑does cell-communicating ingredient
Matrixyl synthe'6 - A peptide that is claimed to be able to boost the production of 6 major components of the skin matrix (including collagen and hyaluronic acid). [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Hydroxypropyl Cyclodextrin
It's a "lifting" ingredient coming from plant raw materials. The manufacturer claims that it moisturizes, gives the skin softness and smoothness, and helps make-up to stay on after application. [more]
,
PPG-26-Buteth-26
A helper ingredient that usually comes to the formula coupled with PEG-40 Hydrogenated Castor Oil. The two together work as surfactants and oil solubilizers. [more]
, [more]
PEG-40 Hydrogenated Castor Oil
what‑it‑does emulsifying | surfactant/cleansing
A mildly viscous, amber-colored liquid that works as an emulsifier and surfactant. [more]
,
Polyacrylate Crosspolymer-6
what‑it‑does viscosity controlling
A helper ingredient that helps to thicken up formulas and form a nice gel texture. It leaves a rich, elegant feel with a velvety finish on the skin.
,
Trisodium Ethylenediamine Disuccinate
what‑it‑does chelating
A helper ingredient that helps to neutralize the metal ions in the formula (they usually come from water) so it stays nice longer. [more]
,
Carbomer
what‑it‑does viscosity controlling
A handy white powder that magically converts a liquid into a nice gel formula. [more]
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
,
Ethoxydiglycol
what‑it‑does solvent
A nice odorless liquid used mainly as a superior solubilizer and efficacy booster for cosmetic active ingredients such as vitamin C or benzoyl peroxide. [more]
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
Chlorphenesin.
what‑it‑does preservative | antimicrobial/antibacterial
A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. [more]
[less]

Highlights

Key Ingredients

Cell-communicating ingredient: Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
,
Palmitoyl Tetrapeptide-7
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
,
Palmitoyl Tripeptide-38
what‑it‑does cell-communicating ingredient
Matrixyl synthe'6 - A peptide that is claimed to be able to boost the production of 6 major components of the skin matrix (including collagen and hyaluronic acid). [more]
Skin-identical ingredient: Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]

Show all ingredients by function

Other Ingredients

Antimicrobial/antibacterial: Chlorphenesin.
what‑it‑does preservative | antimicrobial/antibacterial
A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. [more]
Chelating: Trisodium Ethylenediamine Disuccinate
what‑it‑does chelating
A helper ingredient that helps to neutralize the metal ions in the formula (they usually come from water) so it stays nice longer. [more]
Emulsifying: PEG-40 Hydrogenated Castor Oil
what‑it‑does emulsifying | surfactant/cleansing
A mildly viscous, amber-colored liquid that works as an emulsifier and surfactant. [more]
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
Moisturizer/humectant: Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
Preservative: Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
Chlorphenesin.
what‑it‑does preservative | antimicrobial/antibacterial
A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. [more]
Solvent: Aqua (Water)
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Ethoxydiglycol
what‑it‑does solvent
A nice odorless liquid used mainly as a superior solubilizer and efficacy booster for cosmetic active ingredients such as vitamin C or benzoyl peroxide. [more]
Surfactant/cleansing: PEG-40 Hydrogenated Castor Oil
what‑it‑does emulsifying | surfactant/cleansing
A mildly viscous, amber-colored liquid that works as an emulsifier and surfactant. [more]
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
Viscosity controlling: Polyacrylate Crosspolymer-6
what‑it‑does viscosity controlling
A helper ingredient that helps to thicken up formulas and form a nice gel texture. It leaves a rich, elegant feel with a velvety finish on the skin.
,
Carbomer
what‑it‑does viscosity controlling
A handy white powder that magically converts a liquid into a nice gel formula. [more]

Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

Glycerin - goodie
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • Super common, used for more than 50 years
  • Not only a simple moisturizer but plays an important role in keeping the stuff between our skin cells healthy
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

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The GHK part is the important one as it's a type I collagen fragment. When collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more.

Therefore, Palmitoyl Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. 

In Matrixyl 3000, Palmitoyl Tripeptide-1 is coupled with Palmitoyl Tetrapeptide-7  and the duo works in synergy to reduce wrinkles and give younger looking skin. According to the manufacturer's in-vivo (made on real people) test, applying 3% Matrixyl 3000 twice a day for 2 months resulted in all of the following things:

  • 39.4% reduction in surface occupied by deep wrinkles
  • 32.9% reduction in main wrinkle density
  • 19.9% reduction in main wrinkle average depth
  • 16% improvement in roughness
  • 16.2% in lifting effect
  • 5.5% improvement in elasticity
  • 15.5% improvement in skin tone

Manufacturer results, of course, always have to be taken with a pinch of salt, but if you like peptides, the Matryxil 3000 duo is one of the best-proven and most well-known ones and it's something that is worth trying.

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinteleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

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It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.

Also-called: Matrixyl synthe'6 | What-it-does: cell-communicating ingredient

It's a pretty new peptide trade-named MATRIXYL™ synthe’6. The manufacturer claims that it can boost the production of 6 major components of the skin matrix (collagen I, III, IV, fibronectin, hyaluronic acid and laminin 5) that result in more even skin and fewer wrinkles particularly on the forehead and crow's feet. Using 2% of the active for two months daily, women reported a decrease in wrinkles by 31% up to 100%.

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

It goes by the trade name "Phytodermina Lifting" that refers to two things: it's a "lifting" ingredient and it comes from plant raw materials. 

The manufacturer claims that it gives the skin a marked lifting effect, moisturizes, makes the skin soft and smooth, enhances brightness, and helps make-up to stay on after application.

A helper ingredient that usually comes to the formula coupled with PEG-40 Hydrogenated Castor Oil. The two together work as surfactants and oil solubilizers. It's a non-sticky duo that works at low concentration and is often used to solubilize fragrance components into water-based formulas.

A mildly viscous, amber-colored liquid with fatty odor, made from Castor Oil and polyethylene glycol (PEG).

If it were a person, we’d say, it’s agile, diligent & multifunctional. It’s mostly used as an emulsifier and surfactant but most often it is used to solubilize fragrances into water-based formulas.

What-it-does: viscosity controlling

It's a helper ingredient that helps to thicken up formulas and form a nice gel texture. It leaves a rich, elegant feel with a velvety finish on the skin and works over a wide pH range.

Also-called: EDDS | What-it-does: chelating

A helper ingredient that helps to neutralize the metal ions in the formula (they usually come from water) so it stays nice longer. The special property of this particular ingredient is that it's more effective against more problematic ions, like Cu (copper) and Fe (iron) compared to less problematic ones like Ca (calcium)  and Mg (magnesium).

What-it-does: viscosity controlling

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. If you see gel in the name of a moisturizer type thing, chances are carbomer will be in the ingredient list. 

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

What-it-does: solvent

A nice odorless liquid used mainly as a superior solubilizer and efficacy booster for cosmetic active ingredients such as skincare bigshot vitamin C, self-tanning active DHA or the anti-acne gold standard, benzoyl peroxide

Other than that it can also be used in hair care products where it gives a longer-lasting and more uniform coloring. According to a manufacturer, it might even prevent the formation of split ends.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

A little helper ingredient that works as a preservative. It works against bacteria and some species of fungi and yeast. It's often combined with IT-preservative, phenoxyethanol.

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