Essential Regenerating Night Serum
Ingredients overview
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Evan Beau Essential Regenerating Night SerumIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Jojoba is a drought resistant evergreen shrub native to South-western North America. It's known and grown for jojoba oil, the golden yellow liquid coming from the seeds (about 50% of the weight of the seeds will be oil).
At first glance, it seems like your average emollient plant oil: it looks like an oil and it's nourishing and moisturizing to the skin but if we dig a bit deeper, it turns out that jojoba oil is really special and unique: technically - or rather chemically - it's not an oil but a wax ester (and calling it an oil is kind of sloppy).
So what the heck is a wax ester and why is that important anyway? Well, to understand what a wax ester is, you first have to know that oils are chemically triglycerides: one glycerin + three fatty acids attached to it. The fatty acids attached to the glycerin vary and thus we have many kinds of oils, but they are all triglycerides. Mother Nature created triglycerides to be easily hydrolyzed (be broken down to a glycerin + 3 fatty acid molecules) and oxidized (the fatty acid is broken down into small parts) - this happens basically when we eat fats or oils and our body generates energy from it.
Mother Nature also created wax esters but for a totally different purpose. Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Wax esters are on the outer surface of several plant leaves to give them environmental protection. 25-30% of human sebum is also wax esters to give us people environmental protection.
So being a wax ester results in a couple of unique properties: First, jojoba oil is extremely stable. Like crazy stable. Even if you heat it to 370 C (698 F) for 96 hours, it does not budge. (Many plant oils tend to go off pretty quickly). If you have some pure jojoba oil at home, you should be fine using it for years.
Second, jojoba oil is the most similar to human sebum (both being wax esters), and the two are completely miscible. Acne.org has this not fully proven theory that thanks to this, jojoba might be able to "trick" the skin into thinking it has already produced enough sebum, so it might have "skin balancing" properties for oily skin.
Third, jojoba oil moisturizes the skin through a unique dual action: on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer; on the other hand, it absorbs into the skin through pores and hair follicles then diffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple.
On balance, the point is this: in contrast to real plant oils, wax esters were designed by Mother Nature to stay on the surface and form a protective, moisturizing barrier and jojoba oil being a wax ester is uniquely excellent at doing that.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Aloe Vera is one of today’s magic plants. It does have some very nice properties indeed, though famous dermatologist Leslie Baumann warns us in her book that most of the evidence is anecdotal and the plant might be a bit overhyped.
What research does confirm about Aloe is that it’s a great moisturizer and has several anti-inflammatory (among others contains salicylates, polysaccharides, magnesium lactate and C-glucosyl chromone) as well as some antibacterial components. It also helps wound healing and skin regeneration in general. All in all definitely a goodie.
This ingredient name is not according to the INCI-standard. :( What, why?!
- It’s the most researched AHA with the most proven skin benefits
- It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
- It can help skin’s own collagen production that results in firmer, younger skin
- It can fade brown spots caused by sun damage or PIH
- Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
- Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
- Slight stinging or burning with a stronger AHA product is normal
- If your skin is very sensitive, rosacea prone choose rather a BHA or PHA product
A very stable and promising form of the skincare superstar, Vitamin C. If you do not know why Vitamin C is such a big deal in skin care, you can catch up here. In short, Vitamin C has three proven magic abilities: antioxidant, collagen booster, and skin brightener. The problem, though, is that it's very unstable, turns brown and becomes ineffective in no time (after a few month) and the cosmetics industry is trying to come up with smart derivatives that are stable and have the magic properties of pure Vitamin C.
Ethyl Ascorbic Acid or EAC for short is an "etherified derivative of ascorbic acid" that consists of vitamin C and an ethyl group bound to the third carbon position. This makes Vitamin C very stable and soluble in both water and oil.
However, for a Vitamin C derivative to work it's not enough just to be stable, they also have to be absorbed into the skin and be converted there to pure Vitamin C. We have good news regarding the absorption: on top of manufacturer claims, there is some data (animal study) demonstrating in can get into the skin, and it seems to be better at it than Ascorbyl Glucoside, another vitamin C derivative.
Regarding conversion, we can cite only a manufacturers claim saying that EAC is metabolized in the skin into pure ascorbic acid (and the ascorbic acid content of EAC is very high - 86,4% - compared to the usual 50-60% Vitamin C content of other derivatives).
As for the three magic abilities of Vitamin C, we again mostly have only the manufacturer's claims, but at least those are very promising. EAC seems to have both an antioxidant and anti-inflammatory effect, and it's claimed to be able to boost the skin's collagen production. The strong point of EAC though is skin brightening. On top of manufacturer claims, there is also clinical in-vivo (tested on real people) data showing that 2% EAC can improve skin tone and whiten the skin.
Overall, Ethyl Ascorbic Acid is a very promising but not a fully proven Vitamin C derivative. It's worth a try, especially if you are after Vitamin C's skin-brightening effects.
Ornithine is an amino acid that is the active ingredient in the skin-plumping active trade named Adipofill'In. According to the manufacturer, Adipofill'In is able to increase fatty tissue volume by activating the transcription factor called HIF-1α and thus it has a lipofilling-like effect through a non-invasive method.
It is supposed to be an especially useful active for deep wrinkles, such as the nasolabial fold (the wrinkle between the nose and mouth). In their in-vivo test made with 20 volunteers using 2% Adipofill'In cream twice a day for 60 days, the manufacturer measured up to 37.6% reduction of wrinkle depth and up to 27.5% reduction of skin roughness.
A type of lipid that's the major (about 75%) component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient.
It has a water-loving head with two water-hating tails and this structure gives the molecule emulsifying properties. It is also often used to create liposomes, small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and help its absorption.
We don't have description for this ingredient yet.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
We don't have description for this ingredient yet.
Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved.
It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula.
A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.
This ingredient name is not according to the INCI-standard. :( What, why?!
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
We have to admit that Algae Extract is not our favorite ingredient name. It does comply with the INCI standard (the official list about how ingredients on the product labels have to be called, the thing we help you to decode here :)), but there are about 20 000 different kinds of algae and an extract from them can be made in another 10 000 ways.
So, Algae Extract can be anything from La Mer's "Miracle Broth" to a simple brown algae extract that helps to smooth the hair. The official description in the Europiean Cosmetic Ingredient listing is this: "an extract of various species of Algae; Extract of the Seaweed, Fucus vesiculosus, Furaceae". Its official functions include being a humectant (helps skin to attract water), emollient (makes skin feel smooth and nice) and skin conditioner (a catchall phrase for saying it does something good for the skin).
A 2015 research paper on the potential of uses of algae in cosmetics summarizes that algae are rich sources of biologically active metabolites including antioxidants, anti-inflammatory agents, alginates, polysaccharides, and carotenoids. Currently, algae extracts are mostly used as moisturizing and thickening agents, but algae also have great potential to combat skin aging, pigmentation as well as working as an antimicrobial.
We have also browsed through Prospector to see what manufacturers say about their algae. There is, for example, an algae extract trade-named Lanablue that comes from blue-green algae (green algae is rare, less than 1% of the total macroalgae in the world) and is claimed to have retinoid like effects (i.e. reduce wrinkles, smooth skin) but without the side effects (though it seems now that the INCI name of Lanablue was changed to Aphanizomenon Flos-Aquae Extract).
There is another algae extract from another manufacturer that comes from red algae (much more common, about 40% of total macroalgae worldwide) and is claimed to have not only moisturizing but also skin smoothing and densifying effects.
Here is a brown algae extract (the most common type, about 59% of macroalgae), also just called Algae Extract on the product label that is simply claimed to be a free radical scavenger, aka antioxidant. These were just three random examples from three manufacturers all called Algae extract even though they all come from different algae with different claims.
Anyhow, the point is this; there are tons of different types of Algae Extracts out there. Unless the brand tells you what they use, it's impossible to know for sure. The most probable scenario for the Alge Extract is that it works as a moisturizer and emollient and it might have some additional anti-aging properties.
It's a pretty new anti-aging ingredient that is a "safe and pre-activated source of energy to feed aging skin cells".
It's part of an anti-aging complex trade named Neodermyl, where methylglucoside phosphate is combined with the essential amino acids proline, lysine and also copper. This complex is claimed to be able to increase the collagen I and III production of skin and even more surprisingly, also the elastin production. Both slow down with age and beeing able to boost the skin's own production of these super important proteins results in improved skin firmness and elasticity.
This is a very big deal, especially the elastin part, as there is not yet a clinically proven active ingredient that is able to boost the skin's own elastin production. There are also very few ones (think vitamin C, glycolic acid, and retinol) that are proven to boost collagen. The claims about Neodermyl are not yet confirmed in independent studies but the manufacturer did do some very convincing testing that showed a visible reduction of wrinkle depth and volume in just 15 days. If you are into anti-aging, this is a new active that might be worth a try.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
A newer and, molecule-wise, somewhat bigger version of the famous "Botox-like" peptide called Acetyl Hexapeptide-8 or Argireline. Just like Argireline, Acetyl Octapeptide-3 is also claimed to influence the muscle contraction process that results in a more relaxed and line-free face, especially around the forehead and the eyes.
While Argireline counts as a pretty well-proven peptide, with multiple studies confirming its anti-wrinkle efficacy, we cannot say the same for Acetyl Octapeptide-3. What we have is the manufacturer's claim that comparing 10% Argireline with 10% SNAP-8 solution (that means 0.005% pure peptide powder) the SNAP-8 peptide did a bit better as it reduced wrinkles by 34.98% vs 27.05% reduction for Argireline (twice a day use for 28 days on 17 women).
Other than that, we can write here pretty much the same as at Argireline. Obviously, no peptide works as effectively as real Botox, and the Botox-inspired peptides are quick fixes rather than being collagen builders or real preventers of structural aging. They are nice additions to an anti-aging skincare routine but not the real superstars (think vitamin C, AHAs or retinol).
If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline.
So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?).
The manufacturer did several studies to prove that Argireline really works and it does (just not as well as Botox). In-vivo (made on real people) tests showed that using 10% Argireline solution around the eyes for 15 days decreased wrinkles depth by 17%, while a 5% Argireline formula applied for 28 days did almost the same with a decrease in wrinkle depth by 16.26%. A Spanish University also did some research and found that Argireline increased the level of skin moisturization and decreased both the depth and width of wrinkles "significantly".
This means, Acetyl Hexapeptide-8 does have some ability to smooth wrinkles (but not as well as Botox - sorry, if we sound like a broken record). Also, we have to agree with TruthInAging, that it's not a collagen builder and not a preventer of structural aging (think vitamin C, AHAs or retinol); it's just a quick fix. If you are looking for one, this could be your thing. If you are more of a "let's treat this aging thing properly" type, then it's probably not your thing.
An essential amino acid - mineral complex that is part of the pretty new anti-aging complex called Neodermyl. The manufacturer claims that the complex is able to boost skin's own collagen I and III as well as elastin production. Read more details at methylglucoside phosphate.
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what‑it‑does | solvent |
what‑it‑does | emollient |
irritancy, com. | 0, 0-2 |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | soothing | moisturizer/humectant |
what‑it‑does | exfoliant | buffering |
what‑it‑does | antioxidant | skin brightening |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | skin-identical ingredient | emollient |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | antioxidant | skin brightening |
what‑it‑does | solvent | moisturizer/humectant |
what‑it‑does | emollient | emulsifying |
what‑it‑does | preservative |
what‑it‑does | emollient | moisturizer/humectant |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | antioxidant |
irritancy, com. | 0-3, 0-3 |
what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
what‑it‑does | cell-communicating ingredient | moisturizer/humectant |
what‑it‑does | cell-communicating ingredient | moisturizer/humectant |
what‑it‑does | cell-communicating ingredient |