Precious Fluids
Ingredients overview
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Prana Spaceuticals Precious FluidsIngredients explained
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
This ingredient name is not according to the INCI-standard. :( What, why?!
There are several types of ceramides both in the skin and used in cosmetic products. Read more about ceramides here >>
A four amino acid, biomimetic (i.e. a molecule in nature is copied synthetically in a lab) peptide that copies a growth factor that boosts the production of key components of the dermal-epidermal junction (the place where the top two layers of the skin meet). These key components are important skin-structure giving proteins such as collagen VII, laminin-5, and fibronectin.
What this means in practice, and according to the in-vivo (made on people) tests of the manufacturer, is that Caprooyl Tetrapeptide-3 might be able to reduce the appearance of fine lines and wrinkles. The clinical study had 27 volunteers who used a 2.5% ChroNOline (the diluted and trade named version of our peptide molecule) cream twice a day and the researchers measured a 16% percent reduction in fine lines and wrinkles after 28 days. In mature volunteers (aged 50-65 ), the improvement continued to a reduction of 27% after 56 days.
A six amino acid peptide that is claimed to improve firmness and skin tone. Its amino acid sequence is Val-Gly-Val-Ala-Pro-Gly that is also called the "spring fragment" and is repeated six times in the important skin protein, elastin molecule.
The manufacturer made a double-blind, one-month long clinical study on 10 women and found that twice a day application of 4% Biopeptide El improved skin firmness by 33% and skin tone by 20%.
A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration.
It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time.
It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.
A four amino acid peptide that is claimed to improve puffy eye bags via its anti-oedema and anti-glycation effects.
To back this claim up, the manufacturer created an in-vivo study with 20 volunteers using 10% of EYESERYL (that comes down to 0.01% (!) of the pure peptide) and found that by day 15, 70% of the volunteers improved, while 95% of the volunteers improved by the end of the study (60 days). About third of them improved only slightly, third of them showed an ok improvement and third showed a good improvement. They also have pretty convincing before and after photos, so we can tell you that for the lucky ones, the improvement can be real and visible.
But, the thing is that puffiness around the eyes can have multiple reasons and one of the major ones is fat accumulation that might happen as we age. No miracle cream or ingredient can do much about that, however, another common reason is water accumulation. If the reason behind your eye bags is this latter one, trying an eye cream with Acetyl Tetrapeptide-5 can be a good idea and might bring nice improvements.
A five amino-acid peptide that is claimed to target expression wrinkles that appear due to facial movements. Its effect is similar to the older and more famous Argireline peptide. They achieve similar results but in a different way.
The two together work in a synergistic way (the solution is trade named Argirelox) hindering the muscle contraction process in two different stages. The in-vivo (made on real people) test by the manufacturer showed that after 28 days 5% Leuphasyl alone reduced wrinkles by 11% and 5% Leuphasyl + 5% Argireline reduced wrinkles on average by 25% with max values up to 47%.
We don't have description for this ingredient yet.
If you have already heard of the "plant stem cells trend" in beauty products you probably know about this guy as it was the first ingredient based on plant stem cells on the cosmetic market. It's a liposomal preparation of apple stem cells but not just any apples. It comes from the rare swiss apple called "Uttwiler Spätlauber" (btw, the manufacturer is also Swiss) and the stem cells are claimed to be rich in epigenetic factors and metabolites, which might support the longevity of skin cells.
As for now, we only have the claims of the manufacturer and those are also largely based on in-vitro tests (made in the lab and might or might not translate to real skin). Mibelle (the Swiss manufacturer) did one in-vivo (made on real people) study with 20 women that found that a 2% Malus Domestica Fruit Cell Culture cream applied twice daily decreased wrinkle depth of the crow's feet area by 15% in 4 weeks.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration.
It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time.
It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Astragalus Membranaceus, or Huangqi as the Chinese call it, is one of their most important medicinal herbs that is traditionally used to strengthen "qi", the body’s life force. It has a bunch of magic abilities including tonic, liver-protecting, immunomodulating, antihyperglycemic, anti-inflammatory, antioxidant, and antiviral properties.
Modern research does prove that Huangqi is a valuable medicinal herb and contains plenty of bioactive compounds such as saponins, flavonoids, and polysaccharides. As for skincare and Huangqi, it is well known and used for its general tonic and skin reinforcing properties, as well as for its anti-inflammatory and antioxidant action.
On top of that, we also found a manufacturer claiming that Astragalus Membranaceus Root Extract combines anti-aging and anti-blemish properties so it is especially useful for aging, acne-prone skin. In their in-vivo (made on real people) studies, 2% of liposomal Huangqi increased skin hydration, firmness, and smoothness by 20% after 14 days and decreased "blemish-prone skin signs" by 10-15% after 42 days.
We love a cold slice of watermelon on a hot summer day and we love watermelon as a skincare ingredient. It's really full of good-for-the-skin stuff: it contains a bunch of vitamins (A, B, C and E), mineral salts (K, Mg, Ca and Fe), amino acids citrulline and arginine and antioxidant carotenoids and phenolics.
It's especially rich in potent antioxidant, lycopene (a type of carotenoid), the cool pigment that's responsible for the red color of the watermelon. According to manufacturer info, in-vitro (made in the lab not on real people) studies show that watermelon extract gives significant DNA protection against UV damage. The in-vivo (made on real people) study also confirmed this and the watermelon formula showed 25% increase in skin protection compared to placebo.
All in all, a cool fruit extract with potent antioxidant magic abilities.
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