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Isntree C-Niacin Toning Ampoule

C-Niacin Toning Ampoule

An intensive whitening serum that helps reducing the appearance of discolouration while delivering hydration.
Uploaded by: melioraspero on 24/06/2018

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Hippophae Rhamnoides Fruit Extract
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Water solvent
Pentylene Glycol solvent, moisturizer/​humectant
Niacinamide (4%) cell-communicating ingredient, skin brightening, anti-acne, moisturizer/​humectant superstar
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Betaine moisturizer/​humectant goodie
Aloe Barbadensis Leaf Extract soothing, emollient, moisturizer/​humectant goodie
Melia Azadirachta Flower Extract
Melia Azadirachta Leaf Extract
Cucurbita Pepo Fruit Extract
Physalis Alkekengi Fruit Extract
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Dipotassium Glycyrrhizate soothing goodie
Ocimum Sanctum Leaf Extract
Beta-Glucan soothing, moisturizer/​humectant goodie
Curcuma Longa Root Extract antioxidant, soothing, skin brightening goodie
Corallina Officinalis Extract
Brassica Oleracea Italica Extract
Coccinia Indica Fruit Extract
Moringa Oleifera
Panthenol soothing, moisturizer/​humectant 0, 0 goodie
Allantoin soothing 0, 0 goodie
Bioflavonoids soothing
3-O-Ethyl Ascorbic Acid antioxidant, skin brightening goodie
Sodium Polyacrylate viscosity controlling
Tocopherol antioxidant 0-3, 0-3 goodie
Polysorbate 80 emulsifying 0, 0
1,2-Hexanediol solvent
Ethyl Hexanediol solvent
Ammonium Acryloyldimethyltaurate/Vp Copolymer viscosity controlling
Zanthoxylum Piperitum Fruit Extract antioxidant, antimicrobial/​antibacterial, preservative
Pulsatilla Koreana Extract antimicrobial/​antibacterial, preservative

Isntree C-Niacin Toning Ampoule
Ingredients explained

Also-called: Sea Buckthorn Berry Extract

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

Niacinamide (4%) - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Betaine - goodie
What-it-does: moisturizer/humectant

A sugar beet derived amino acid derivative with nice skin protection and moisturization properties. Betain's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

Also-called: Aloe Leaf Extract | What-it-does: soothing, emollient, moisturizer/humectant

The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though  oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Pumpkin Extract

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

Also-called: Licorice | What-it-does: soothing

The salt form of one of the main anti-inflammatory ingredients in the licorice plant, monoammonium glycyrrhizinate. It’s a yellowish powder with a nice sweet smell. 

It’s used mainly for its soothing and anti-inflammatory properties, but according to manufacturer info, it’s also sebum regulating so it's a perfect ingredient for problem skin products. 

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Read more about licorice and why it's a skincare superstar here. 

We don't have description for this ingredient yet.

Beta-Glucan - goodie

Beta-Glucan is a nice big molecule composed of many smaller sugar molecules (called polysaccharide). It’s in the cell walls of yeast, some mushrooms, seaweeds, and cereals.

It’s a real goodie no matter if you eat it or put it on your face. Eating it is anti-diabetic, anti-cancer and even lowers the blood cholesterol. 

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Putting it on your face it also does a bunch of good things: it ‘s shown to have wound healing properties, it’s a mild antioxidant,  it’s a great skin soother and moisturizer, and it even shows promising anti-aging benefits

The manufacturer of the ingredient did a published study with 27 people and examined the effect of 0.5% beta-glucan. They found that despite the large molecular size beta-glucan does penetrate into the skin, even into the dermis (the middle layer of the skin where wrinkles form). After 8 weeks there was a significant reduction of wrinkle depth and height and skin roughness has also improved greatly. 

Bottom line: Beta-glucan is a great ingredient, especially for sensitive skin. It soothes, moisturizes and even shows some anti-aging magic properties. 

Also-called: Turmeric Root Extract | What-it-does: antioxidant, soothing, skin brightening

Turmeric is the yellow spice you probably know from curry and Indian food. It's also a traditional herbal medicine used in Ayurveda for its bunch of anti-something magic abilities including being anti-inflammatory, antimicrobial, antioxidant and anticarcinogenic. 

As for turmeric and skincare, we have good news: studies show that the root extract and its main biologically active component, curcumin can do multiple good things for the skin. Thanks to its anti-inflammatory and antimicrobial activity, it shows some promise for acne-prone skin and a small study from 2013 showed that it might be able to regulate sebum production

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It's also a potent antioxidant and skin-brightening agent so it often shows up in anti-aging and/or radiance-boosting products. 

We don't have description for this ingredient yet.

Also-called: Broccoli Extract | What-it-does: astringent

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

This ingredient name is not according to the INCI-standard. :( What, why?!

Panthenol - goodie
Also-called: Pro-Vitamin B5 | What-it-does: soothing, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

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Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.

Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation. 

If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.

As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily. 

Allantoin - goodie
What-it-does: soothing | Irritancy: 0 | Comedogenicity: 0

Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically. 

It's not only soothing but it' also skin-softening and protecting and can promote wound healing.

What-it-does: soothing

We don't have description for this ingredient yet.

Also-called: Form of Vitamin C, 3-O-Ethyl Ascorbate, EAC;Ethyl Ascorbic Acid | What-it-does: antioxidant, skin brightening

A very stable and promising form of the skincare superstar, Vitamin C. If you do not know why Vitamin C is such a big deal in skin care, you can catch up here. In short, Vitamin C has three proven magic abilities: antioxidant, collagen booster, and skin brightener. The problem, though, is that it's very unstable, turns brown and becomes ineffective in no time (after a few month) and the cosmetics industry is trying to come up with smart derivatives that are stable and have the magic properties of pure Vitamin C. 

Ethyl Ascorbic Acid or EAC for short is an "etherified derivative of ascorbic acid" that consists of vitamin C and an ethyl group bound to the third carbon position. This makes Vitamin C very stable and soluble in both water and oil.

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However, for a Vitamin C derivative to work it's not enough just to be stable, they also have to be absorbed into the skin and be converted there to pure Vitamin C. We have good news regarding the absorption: on top of manufacturer claims, there is some data (animal study) demonstrating in can get into the skin, and it seems to be better at it than Ascorbyl Glucoside, another vitamin C derivative.

Regarding conversion, we can cite only a manufacturers claim saying that EAC is metabolized in the skin into pure ascorbic acid (and the ascorbic acid content of EAC is very high - 86,4% - compared to the usual 50-60% Vitamin C content of other derivatives). 

As for the three magic abilities of Vitamin C, we again mostly have only the manufacturer's claims, but at least those are very promising. EAC seems to have both an antioxidant and anti-inflammatory effect, and it's claimed to be able to boost the skin's collagen production. The strong point of EAC though is skin brightening. On top of manufacturer claims, there is also clinical in-vivo (tested on real people) data showing that 2% EAC can improve skin tone and whiten the skin. 

Overall, Ethyl Ascorbic Acid is a very promising but not a fully proven Vitamin C derivative. It's worth a try, especially if you are after Vitamin C's skin-brightening effects. 

A superabsorbent polymer (big molecule from repeated subunits) that has crazy water binding abilities. Sometimes its referred to as "waterlock" and can absorb 100 to 1000 times its mass in water. 

As for its use in cosmetic products, it is a handy multi-tasker that thickens up water-based formulas and also has some emulsifying and emulsion stabilizing properties. 

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: emulsifying | Irritancy: 0 | Comedogenicity: 0

A common little helper ingredient that helps water and oil to mix together, aka emulsifier. 

The number at the end refers to the oil-loving part and the bigger the number  the more emulsifying power it has. 20 is a weak emulsifier, rather called solubilizer used commonly in toners while 60 and 80 are more common in serums and creams.

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

What-it-does: solvent

A colorless, slightly viscous liquid that, similar to other glycols, is used as a solvent in cosmetic products. Its recommended concentration is less than 5%. 

Also-called: Aristoflex AVC;Ammonium Acryloyldimethyltaurate/VP Copolymer | What-it-does: viscosity controlling

A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky. 

It works over a wide pH range and is used between 0.5-1.2%.

Also-called: Japanese Pepper, Korean Pepper, Sanshō, Chopi | What-it-does: antioxidant, antimicrobial/antibacterial, preservative

If you are into Japanese cuisine, you might know this guy as Japanese pepper or Sanshō pepper that is known for its unique fresh aroma and appetite increasing spicy sensation.

As for the skin benefits of Zanthoxylum Piperitum, it might have antioxidant effects (with active components called hyperoside and quercitrin), but more importantly, it is an antibacterial and natural preservative agent. It is pretty common in K-Beauty products, as it's one of the three natural extracts that make up the popular Korean preservative called EURO-NApre. 

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Combined with Usnea Barbata and Pulsatilla Koreana, these three extracts are claimed to form a natural preservative system that also has anti-inflammatory effects and might help with skin conditions such as blemishes, atopic dermatitis, and dandruff. 

On the flip side, Zanthoxylum Piperitum contains fragrant components (Limonene and Citrone), that might irritate sensitive skin. 

Also-called: Korean Pasque Flower Extract | What-it-does: antimicrobial/antibacterial, preservative

The extract of Korean Pasque Flower that is mostly used for its antimicrobial and natural preservative activities. It usually comes to the formula combined with Zanthoxylum Piperitum and Usnea Barbata, as the three extracts make up a popular Korean natural preservative system trade named EURO-NApre.  

The plant extract is also a traditional oriental herbal medicine that is known for its analgesic, anti-inflammatory, and astringent effects. 

You may also want to take a look at...

what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does moisturizer/humectant
A sugar beet derived amino acid derivative with nice skin protection and moisturization properties. Its special thing is being an osmolyte, a molecule that helps to control cell-water balance.  [more]
what‑it‑does soothing | emollient | moisturizer/humectant
The extract coming from the juice containing leaves of the Aloe vera plant with moisturizing, emollient and anti-inflammatory properties. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does soothing
The salt form of one of the main anti-inflammatory ingredients in the licorice plant, monoammonium glycyrrhizinate. It’s a yellowish powder with a nice sweet smell.  It’s used mainly for its soothing and anti-inflammatory properties, but according to manufacturer info, it’s also sebum regulating so it' [more]
what‑it‑does soothing | moisturizer/humectant
A great skin soother and moisturizer, and it even shows promising anti-aging benefits. It‘s also shown to have wound healing properties and is a mild antioxidant. [more]
what‑it‑does antioxidant | soothing | skin brightening
Turmeric Root Extract that has nice anti-inflammatory, antioxidant and skin-brightening properties. [more]
what‑it‑does soothing | moisturizer/humectant
irritancy, com. 0, 0
Pro-Vitamin B5 is a goodie that moisturises the skin, has anti-inflammatory, skin protecting and wound healing properties. [more]
what‑it‑does soothing
irritancy, com. 0, 0
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically. It's not only soothing but it' [more]
what‑it‑does soothing
what‑it‑does antioxidant | skin brightening
A stable form of Vitamin C, whose strong point is skin-brightening. It might also have antioxidant, anti-inflammatory and collagen boosting abilities. [more]
what‑it‑does viscosity controlling
A big polymer (a molecule from repeated subunits) with crazy water binding abilities. Used as a thickening and emulsion stabilizing agent. [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does emulsifying
irritancy, com. 0, 0
A common little helper ingredient that helps water and oil to mix together, aka emulsifier. [more]
what‑it‑does solvent
A multi-functional helper ingredient that acts as a humectant and emollient. It's also a solvent and can boost the effectiveness of preservatives. [more]
what‑it‑does solvent
A colorless, slightly viscous liquid that, similar to other glycols, is used as a solvent in cosmetic products. Its recommended concentration is less than 5%.  [more]
what‑it‑does viscosity controlling
A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. [more]
what‑it‑does antioxidant | antimicrobial/antibacterial | preservative
Japanese pepper extract that has natural antibacterial and preservative activities. Combined with Usnea Barbata and Pulsatilla Koreana, it is part of a popular Korean preservative system called EURO-NApre. [more]
what‑it‑does antimicrobial/antibacterial | preservative
The extract of Korean Pasque Flower that is mostly used for its antimicrobial and natural preservative activities. It usually comes to the formula combined with Zanthoxylum Piperitum and Usnea Barbata, as the three extracts make up a popular Korean natural preservative system trade named EURO-NApre.  [more]