Anti-Stress Balance Serum
Highlights
Key Ingredients
Other Ingredients
Skim through
| Ingredient name | what-it-does | irr., com. | ID-Rating |
|---|---|---|---|
| Aqua | solvent | ||
| Panthenol | soothing, moisturizer/humectant | 0, 0 | goodie |
| Squalane | skin-identical ingredient, emollient | 0, 1 | goodie |
| Glycerin | skin-identical ingredient, moisturizer/humectant | 0, 0 | superstar |
| Hydroxypropyl Starch Phosphate | viscosity controlling | ||
| C14-22 Alcohols | |||
| Ectoin | antioxidant, soothing, moisturizer/humectant | goodie | |
| C12-20 Alkyl Glucoside | emulsifying, surfactant/cleansing | ||
| Sodium Stearoyl Glutamate | emulsifying, surfactant/cleansing | ||
| Glucose | moisturizer/humectant | goodie | |
| Sclerotium Gum | viscosity controlling | ||
| Citric Acid | buffering | ||
| Ethylhexylglycerin | preservative | ||
| Phenoxyethanol | preservative |
Isana Anti-Stress Balance SerumIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
We don't have description for this ingredient yet.
A 100% vegetable origin emulsifier that usually comes to the formula with its buddy called C12-20 Alkyl Glucoside. The duo is trade-named Montanov L and works as an effective oil in water emulsifier. It creates ultra-soft, light texture, has excellent dermo-compatibility and is readily biodegradable.
Chemically speaking, it is a mixture of fatty alcohols with 14 to 22 carbon atoms in their fatty chains.
Ectoin is a surprisingly well-researched, multi-functional active that can do from pollution & light protection to skin hydration, soothing, and barrier repair, several things to your skin.
It is an extremolyte, a small stress-protection molecule that protects microorganisms living under extreme conditions such as salt lakes, hot springs, arctic ice, the deep sea, or deserts. It was discovered in 1985 in a microorganism living in a salt lake in the Egyptian desert.
The key skill of Ectoin is protection that applies also to the skin. Its main mode of action is binding water molecules (aka kosmotropic) and creating hydro complexes. These complexes then surround important biomolecules (e.g. cells, proteins, enzymes) and form a stabilizing hydration shell around them.
This protection mechanism means good things when it comes to our skin: Ectoin has antioxidant, anti-inflammatory, pollution& light protecting, skin hydrating, barrier repairing as well as anti-aging properties.
A placebo-controlled 10-person study examined a four-week treatment with 0.5% Ectoin in the crow's feet area and found a significant anti-wrinkle effect (-19% mean wrinkle depth) in 100% of the participants. Another double-blind, placebo-controlled clinical study with 24 participants used a 2% Ectoin cream twice a day for 4 weeks and found an improvement in all of the measured parameters, such as wrinkle volume, skin scaling, roughness, and elasticity.
Another remarkable property of Ectoin is protecting the epidermal immune cells called Langerhans cells from UV damage. 0.3% and 0.5% Ectoin cream was used twice a day for 14 days on the forearm and then irradiated with 1.5 MED UV (one and a half times the UV dose that causes detectable redness). While the untreated, UV-stressed area showed a 40% decrease in viable Langerhans cells, 0.5% Ectoin showed 100% protection (and 0.3% showed ~95% protection).
The soothing efficacy is also backed up by multiple in-vivo studies. A 20-person study compared 1% Ectoin cream to 0.25% hydrocortisone treatment on surfactant irritated skin and found similar effectiveness in reducing skin redness. Another study with 23 females with sensitive skin found that a 1% Ectoin cream helped to tolerate a 0.5% or 1% retinol treatment much better.
A tiny, 5-person study examined the long-term (7 days) skin hydration effect of 1% Ectoin. During the study, hydration levels increased up to 200% compared to placebo, and even 7 days after stopping the treatment hydration status was largely preserved. Higher concentration (5-7%) Ectoin treatments are also used as OTC medical products for the treatment of eczema or atopic skin.
The anti-pollution magic properties are also well-established and Ectoin is currently the only anti-pollution active ingredient approved for use in medical products (e.g. inhalation solutions) in Europe. Clinical studies showed a reduction of inflammations in human lungs of patients with COPD (a pulmonary disease) and pollution-induced asthma. But coming back to the skin, Ectoin protects both from PMs (Particulate Matters, including ultrafine) as well as PAHs (Polycyclic Aromatic Hydrocarbons) and heavy metals.
If that weren't enough, Ectoin is also shown to protect the skin from blue and visible light, and pigmentation resulting from environmental stress (think UV, pollution, oxidative stress).
All in all, we think Ectoin is one of those under-the-radar actives that deserves more hype than it is currently getting. As an amazing all-around skin protectant, it is a useful addition to any skincare routine.
A 100% vegetable origin emulsifier that usually comes to the formula with its buddy called C14-22 Alcohols. The duo is called Montanov L and two together help to create ultra-soft light formulas.
An amino acid-based emulsifier that helps water and oil to mix and stay that way. It is considered as natural, environmentally friendly, and hypoallergenic.
A fancy name for sugar. Luckily when you put it on your skin it's good for you not like when you eat it. :) It has water-binding properties, which means that it helps to keep your skin nice and hydrated.
A big sugar molecule (polysaccharide) that is used as a natural thickening and gelling agent. It is similar to more commonly used Xanthan Gum, and the two are also often combined to create gel formulas or to stabilize emulsions.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
You may also want to take a look at...
| what‑it‑does | solvent |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | antioxidant | soothing | moisturizer/humectant |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | viscosity controlling |
| what‑it‑does | buffering |
| what‑it‑does | preservative |
| what‑it‑does | preservative |