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Glow Lab Facial Serum

Facial Serum

A multi-active serum with Matrixyl® Synthe' 6™ ProRenew Complex CLR™ and SymRelief® 100 (ginger root extract) deliver a powerful blend to accelerate skin renewal, calm irritation and reduce the appearance [more] [more] of fine lines by 31%. Vitamins A & E provide antioxidant benefits for hydrated, glowing skin. [less]
Uploaded by: beeonacar on 16/08/2019

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water (Aqua) solvent
Coco-Caprylate emollient
Lactococcus Ferment Lysate (Prorenew Complex Clr™) goodie
Butyrospermum Parkii (Shea) Butter emollient goodie
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Hydroxypropyl Cyclodextrin goodie
Palmitoyl Tripeptide-38 (Matrixyl® Synthé 6™) cell-communicating ingredient goodie
Calendula Officinalis (Marigold) Flower Extract soothing, antioxidant goodie
Retinyl Palmitate (Vitamin A) cell-communicating ingredient 1-3, 1-3
Tocopherol (Vitamin E) antioxidant 0-3, 0-3 goodie
Diheptyl Succinate emollient
Capryloyl Glycerin/Sebacic Acid Copolymer
Carbomer viscosity controlling 0, 1
Glyceryl Citrate/Lactate/Linoleate/Oleate emulsifying
Solanum Lycopersicum (Tomato) Fruit Extract (Tclc-Ibr®) antioxidant
Bisabolol soothing goodie
Zingiber Officinale (Ginger) Root Extract (Symrelief® 100) antioxidant, soothing goodie
Benzyl Alcohol preservative, perfuming, solvent, viscosity controlling
Dehydroacetic Acid (Preservatives) preservative
Sodium Phytate (Chelating Agent) chelating
Sodium Hydroxide (Ph Modifier) buffering
Fragrance (Essential Oil Blend*) perfuming icky
Benzyl Benzoate solvent, perfuming, antimicrobial/​antibacterial icky
Benzyl Salicylate perfuming icky
Citronellol perfuming icky
Hexyl Cinnamaldehyde perfuming icky
Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde perfuming
Butylphenyl Methylpropional perfuming icky
Limonene perfuming, solvent icky
Linalool perfuming icky

Glow Lab Facial Serum
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

What-it-does: emollient

A clear, colorless to slightly yellowish oil that makes the skin nice and smooth (emollient), spreads easily on the skin and is marketed as a good alternative to volatile (does not absorb into the skin but rather evaporates from it) silicones like Cyclomethicone.

Lactococcus Ferment Lysate is a fairly new probiotic ingredient that is obtained from the Gram-positive bacteria, Lactococcus lactis. The lysate is a fluid substance that is produced when you break down the cell membrane, which means it contains interesting things including cytoplasm and cell wall fragments.

According to the manufacturer, it positively influences both the speed and quality of epidermal growth that results in better barrier function and overall skin quality. To prove their point, the German manufacturer conducted several in-vitro (made in test tubes) tests examining how the treatment with Lactococcus Ferment Lysate (LFL) affects important skin proteins.

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They found that the proteins binding the live skin cells together (such as Occludin, Desmocollin 1 and Desmoglein 1) are stimulated by LFL, as well as the enzymes (Kallikrein 5 and 7) breaking the bonds between the shedding dead skin cells. LFL also had a positive influence on epidermal growth and on the thickness of the stratum corneum (the outermost layer of the skin). Another positive finding was that LFL stimulated the production of antimicrobial peptides that play an important role in the immunocompetence of the skin cells.

As for in-vivo tests, the manufacturer only did one and that had only 5 volunteers. They did some tape stripping (exactly what it sounds, hurting the skin by stripping off the top layers) and examined skin renewal and barrier recovery. 4 days after the experiment 3% Lactococcus Ferment Lysate used twice daily resulted in thicker stratum corneum (the difference was about 2 µm) and less trans-epidermal water loss. 

Overall, Lactococcus Ferment Lysate is a promising but fairly unproven ingredient that might help with the natural skin renewal process as well as with a healthy skin barrier and skin flora.  

Also-called: Shea Butter | What-it-does: emollient

Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.

But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

It goes by the trade name "Phytodermina Lifting" that refers to two things: it's a "lifting" ingredient and it comes from plant raw materials. 

The manufacturer claims that it gives the skin a marked lifting effect, moisturizes, makes the skin soft and smooth, enhances brightness, and helps make-up to stay on after application.

Also-called: Matrixyl synthe'6 | What-it-does: cell-communicating ingredient

It's a pretty new peptide trade-named MATRIXYL™ synthe’6. The manufacturer claims that it can boost the production of 6 major components of the skin matrix (collagen I, III, IV, fibronectin, hyaluronic acid and laminin 5) that result in more even skin and fewer wrinkles particularly on the forehead and crow's feet. Using 2% of the active for two months daily, women reported a decrease in wrinkles by 31% up to 100%.

Also-called: Calendula Extract, Marigold Extract | What-it-does: soothing, antioxidant

The extract coming from the popular garden plant Calendula or Marigold. According to manufacturer info, it's used  for many centuries for its exceptional healing powers and is particularly remarkable in the treatment of wounds. It contains flavonoids that give the plant anti-inflammatory and antioxidant properties. 

Also-called: Form of Retinoids | What-it-does: cell-communicating ingredient | Irritancy: 1-3 | Comedogenicity: 1-3

It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the queen being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince William, two steps away from the throne. Retinyl palmitate will be then little Prince George, quite far (3 steps) away from the throne. 

By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:

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retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid

As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective

What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD,  director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre. 

Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here.  It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA. 

We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!

Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.

Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: emollient

Diheptyl Succinate is a natural, "silicone-alternative" emollient that usually comes to the formula with Capryloyl Glycerin/Sebacic Acid Copolymer. The two together is trade-named LexFeel N and depending on their ratio, the duo can mimic both super light, Cyclomethicone-type skin feel as well as more viscous Dimethicone like skin feel. 

The duo also plays well with pure natural oils, and it can reduce their greasiness and tackiness and make them feel nicer on the skin. LexFeel N is also very eco-friendly, 100% natural (Ecocert approved), sustainable and biodegradable. 

The friend of Diheptyl Succinate as the duo is usually used together and is touted as a natural silicone alternative. Read more there >> 

What-it-does: viscosity controlling | Irritancy: 0 | Comedogenicity: 1

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient.

What-it-does: emulsifying

We don't have description for this ingredient yet.

What-it-does: antioxidant

We don't have description for this ingredient yet.

Bisabolol - goodie
Also-called: Alpha-Bisabolol | What-it-does: soothing

It's one of the active parts of Chamomile that contains about 30% of bisabolol. It's a clear oily fluid that is used in skincare as a nice anti-inflammatory and soothing ingredient. 

Also-called: Ginger Root Extract | What-it-does: antioxidant, soothing

The extract coming from ginger, the lovely spice that we all know from the kitchen. It is also a medicinal plant used both in Chinese and Ayurvedic medicine for pretty much everything you can imagine (muscular pain, sore throat, nausea, fever or cramps,  just to give a few examples).

As for ginger and skincare, the root extract contains the biologically active component called gingerol that has potent antioxidant and anti-inflammatory properties. Combined with Bisabololthe duo works synergistically to sooth the skin and take down redness. 

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Other than that, ginger also contains moisturizing polysaccharides, amino acids, and sugars, and it is also quite well known to increase blood circulation and have a toning effect.

Last but not least, Ginger also has some volatile, essential oil compounds (1-3%). Those are mostly present in ginger oil, but small amounts might be in the extract as well (around 0.5% based on manufacturer info). 

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.

No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.  

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In high amounts, it can be a skin irritant, but don’t worry, it’s never used in high amounts.

Also-called: Geogard 111A | What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi and has only milder effect against bacteria. 

It is Ecocert and Cosmos approved, works quite well at low concentrations (0.1-0.6%) and is popular in natural products.

What-it-does: chelating

It’s one of those little helper ingredients that makes sure the product stays the same over time. No color change or anything like that. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. 

Also-called: lye | What-it-does: buffering

The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right. 

For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.  

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BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.

Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.

Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face than fragrance is not your best friend - no way to know what’s really in it.  

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Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!). 

A common fragrance ingredient that has a faint sweet balsamic smell. It can also be a solvent and can fight against microbes and insects very well.

It's one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. Best to avoid if your skin is sensitive.

What-it-does: perfuming

It’s a common fragrance ingredient that has a light floral smell.  It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid if your skin is sensitive.

What-it-does: perfuming

Citronellol is a very common fragrance ingredient with a nice rose-like odor. In the UK, it’s actually the third most often listed perfume on the ingredient lists. 

It can be naturally found in geranium oil (about 30%) or rose oil (about 25%). 

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As with all fragrance ingredients, citronellol can also cause allergic contact dermatitis and should be avoided if you have perfume allergy. In a 2001 worldwide study with 178 people with known sensitization to fragrances citronellol tested positive in 5.6% of the cases.

There is no known anti-aging or positive skin benefits of the ingredient. It’s in our products to make it smell nice. 

What-it-does: perfuming

A common fragrance ingredient that smells like jasmine. It is one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. Best to avoid if your skin is sensitive.

Also-called: Lyral | What-it-does: perfuming

We don't have description for this ingredient yet.

Also-called: Lilial | What-it-does: perfuming

A common fragrance ingredient that has a nice floral scent and also goes by the name Lilial. It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid if your skin is sensitive. 

Limonene - icky
What-it-does: perfuming, solvent, deodorant

A super common and cheap fragrance ingredient. It's in many plants, e.g. rosemary, eucalyptus, lavender, lemongrass, peppermint and it's the main component (about 50-90%) of the peel oil of citrus fruits.

It does smell nice but the problem is that it oxidizes on air exposure and the resulting stuff is not good for the skin. Oxidized limonene can cause allergic contact dermatitis and counts as a frequent skin sensitizer

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Limonene's nr1 function is definitely being a fragrance component, but there are several studies showing that it's also a penetration enhancer, mainly for oil-loving components.

All in all, limonene has some pros and cons, but - especially if your skin is sensitive - the cons probably outweigh the pros.  

Linalool - icky
What-it-does: perfuming, deodorant

Linalool is a super common fragrance ingredient. It’s kind of everywhere - both in plants and in cosmetic products. It’s part of 200 natural oils including lavender, ylang-ylang, bergamot, jasmine, geranium and it can be found in 90-95% of prestige perfumes on the market. 

The problem with linalool is, that just like limonene it oxidises on air exposure and becomes allergenic. That’s why a product containing linalool that has been opened for several months is more likely to be allergenic than a fresh one.

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A study made in the UK with 483 people tested the allergic reaction to 3% oxidised linalool and 2.3% had positive test results. 

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does emollient
A fast-spreading emollient oil that has a similar skin feel to volatile silicones. [more]
A probiotic ingredient that - according to the manufacturer - positively influences both the speed and the quality of epidermal growth that result in better barrier function and overall skin quality. [more]
what‑it‑does emollient
Shea butter that's considered to be a magic moisturizer and emollient. It is also soothing and rich in antioxidants. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
It's a "lifting" ingredient coming from plant raw materials. The manufacturer claims that it moisturizes, gives the skin softness and smoothness, and helps make-up to stay on after application. [more]
what‑it‑does cell-communicating ingredient
Matrixyl synthe'6 - A peptide that is claimed to be able to boost the production of 6 major components of the skin matrix (including collagen and hyaluronic acid). [more]
what‑it‑does soothing | antioxidant
Marigold extract - contains flavonoids that give the plant anti-inflammatory and antioxidant properties. [more]
what‑it‑does cell-communicating ingredient
irritancy, com. 1-3, 1-3
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does emollient
Diheptyl Succinate is a natural, "silicone-alternative" emollient that usually comes to the formula with Capryloyl Glycerin/Sebacic Acid Copolymer. [more]
The friend of Diheptyl Succinate as the duo is usually used together and is touted as a natural silicone alternative. Read more there >>  [more]
what‑it‑does viscosity controlling
irritancy, com. 0, 1
A handy white powder that magically converts a liquid into a nice gel formula. [more]
what‑it‑does emulsifying
what‑it‑does antioxidant
what‑it‑does soothing
One of the active parts of Chamomile that is used in skincare as a nice anti-inflammatory and soothing ingredient. [more]
what‑it‑does antioxidant | soothing
Ginger extract that has antioxidant and soothing properties. It is also known to increase blood circulation and thus have a toning effect. [more]
what‑it‑does preservative | perfuming | solvent | viscosity controlling
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically. No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. [more]
what‑it‑does preservative
A preservative that works mainly against fungi and has only milder effect against bacteria. Popular in natural products.  [more]
what‑it‑does chelating
It’s one of those little helper ingredients that makes sure the product stays the same over time. No color change or anything like that. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.  [more]
what‑it‑does buffering
Lye - A solid white stuff that’s very alkaline and used in small amount to adjust the pH of the product.  [more]
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]
what‑it‑does solvent | perfuming | antimicrobial/antibacterial
A common fragrance ingredient that has a faint sweet balsamic smell. It can also be a solvent and can fight against microbes and insects very well. One of the “EU 26 fragrances” that has to be labelled separately because of allergen potential.
what‑it‑does perfuming
It’s a common fragrance ingredient that has a light floral smell.  It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” [more]
what‑it‑does perfuming
A common fragrance ingredient with a nice rose-like smell. [more]
what‑it‑does perfuming
A common fragrance ingredient that smells like jasmine. It is one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. [more]
what‑it‑does perfuming
what‑it‑does perfuming
A common fragrance ingredient that has a nice floral scent and also goes by the name Lilial. It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” [more]
what‑it‑does perfuming | solvent
A super common fragrance ingredient found naturally in many plants including citrus peel oils, rosemary or lavender. It autoxidizes on air exposure and counts as a common skin sensitizer. [more]
what‑it‑does perfuming
A super common fragrance ingredient that can be found among others in lavender, ylang-ylang, bergamot or jasmine. The downside of it is that it oxidises on air exposure and might become allergenic. [more]