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Lactococcus Ferment Lysate

Lactococcus Ferment Lysate


Official CosIng Information


Lactococcus Ferment Lysate is a fairly new probiotic ingredient that is obtained from the Gram-positive bacteria, Lactococcus lactis. The lysate is a fluid substance that is produced when you break down the cell membrane, which means it contains interesting things including cytoplasm and cell wall fragments.

According to the manufacturer, it positively influences both the speed and quality of epidermal growth that results in better barrier function and overall skin quality. To prove their point, the German manufacturer conducted several in-vitro (made in test tubes) tests examining how the treatment with Lactococcus Ferment Lysate (LFL) affects important skin proteins.

They found that gene expression influencing the proteins binding the live skin cells together (such as Occludin, Desmocollin 1 and Desmoglein 1) is stimulated by LFL, as well as the expression of enzymes (Kallikrein 5 and 7) breaking the bonds between the shedding dead skin cells. LFL also had a positive influence on epidermal growth and on the thickness of the stratum corneum (the outermost layer of the skin). Another positive finding was that LFL stimulated the production of antimicrobial peptides that play an important role in the immunocompetence of the skin cells.

As for in-vivo tests, the manufacturer only did one and that had only 5 volunteers. They did some tape stripping (exactly what it sounds, hurting the skin by stripping off the top layers) and examined skin renewal and barrier recovery. 4 days after the experiment 3% Lactococcus Ferment Lysate used twice daily resulted in thicker stratum corneum (the difference was about 2 µm) and less trans-epidermal water loss. 

Overall, Lactococcus Ferment Lysate is a promising but fairly unproven ingredient that might help with the natural skin renewal process as well as with a healthy skin barrier and skin flora.  

Products with Lactococcus Ferment Lysate

NIOD Voicemail Masque Histoire Naturelle Lactobacillus Lotion Histoire Naturelle Lactobacillus Toner Indeed Labs noAcid Pads NIOD Non-Acid Acid Precursor 15% REN Perfect Canvas Clean Primer Tailor Skincare Renew Elemis Dynamic Resurfacing Facial Pads Esho Drench Glow Lab Facial Serum Glowbiotics Instant Refreshing Gel Hydrator Glowbiotics Probiotic Firming + Replenishing Lotion HydroPeptide Power Serum The Ordinary Buffet The Ordinary Buffet + Copper Peptides 1% City Beauty Invisicrepe Body Balm GALLINÉE Youthful Serum Glowbiotics Gentle Probiotic Calming Lotion H20 Plus Rapids Champagne Illuminator With Champagne And Yuzu Extracts Tula Get Toned Pro-Glycolic 10% Resurfacing Toner Glowbiotics Instant Resurfacing Pads Glowbiotics Probiotic Brightening + Refining Layering Solution Ren Aha Smart Renewal Body Serum Algenist Alive Prebiotic Balancing Mask Chantecaille Gold Recovery Mask Glow Lab Night Cream Tula Keep It Clear Acne Foam Cleanser BIOSSANCE Squalane + Probiotic Gel Moisturizer Dr. Brandt Hydro Biotic Recovery Sleeping Mask HydroPeptide Face Lift Advanced Ultra Light Moisturiser Lumene Nordic-C Valo Overnight Bright Sleeping Cream Missha Time Revolution Immortal Youth Moisturiser Tula Kefir Replenishing Cleansing Oil Tula Multi-Spectrum Eye Renewal Serum Umoua Barrier Repair Essential Emulsion doTERRA Hydrating Cream Sebamed Anti-Pollution Feuchtigkeitsfluid SPF 20 Tula Acne Clearing + Tone Correcting Gel Tula Probiotic Skin Care Aqua Infusion Oil-Free Gel Cream Zelens Z Balance Prebiotic & Probiotic Facial Mist Cosmedix Clarify Salicylic Acid Foaming Cleanser TruAura Replenishing Hand Cream Tula Super Calm Gentle Milk Cleanser Tula Super Soothe Calming Moisturizing Lotion StriVectin Blue Rescue Clay Renewal Mask Tula face filter blurring & moisturizing primer hyggee All-In-One Wrinkle Care Mask hyggee One-Step Facial Essence | Balance Algenist Alive Prebiotic Balancing Moisturizer Spf 15 Hygge All-In-One Mist