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Lactococcus Ferment Lysate

Lactococcus Ferment Lysate



Lactococcus Ferment Lysate is a fairly new probiotic ingredient that is obtained from the Gram-positive bacteria, Lactococcus lactis. The lysate is a fluid substance that is produced when you break down the cell membrane, which means it contains interesting things including cytoplasm and cell wall fragments.

According to the manufacturer, it positively influences both the speed and quality of epidermal growth that results in better barrier function and overall skin quality. To prove their point, the German manufacturer conducted several in-vitro (made in test tubes) tests examining how the treatment with Lactococcus Ferment Lysate (LFL) affects important skin proteins.

They found that the proteins binding the live skin cells together (such as Occludin, Desmocollin 1 and Desmoglein 1) are stimulated by LFL, as well as the enzymes (Kallikrein 5 and 7) breaking the bonds between the shedding dead skin cells. LFL also had a positive influence on epidermal growth and on the thickness of the stratum corneum (the outermost layer of the skin). Another positive finding was that LFL stimulated the production of antimicrobial peptides that play an important role in the immunocompetence of the skin cells.

As for in-vivo tests, the manufacturer only did one and that had only 5 volunteers. They did some tape stripping (exactly what it sounds, hurting the skin by stripping off the top layers) and examined skin renewal and barrier recovery. 4 days after the experiment 3% Lactococcus Ferment Lysate used twice daily resulted in thicker stratum corneum (the difference was about 2 µm) and less trans-epidermal water loss. 

Overall, Lactococcus Ferment Lysate is a promising but fairly unproven ingredient that might help with the natural skin renewal process as well as with a healthy skin barrier and skin flora.  

Products with Lactococcus Ferment Lysate

NIOD Voicemail Masque Histoire Naturelle Lactobacillus Lotion Histoire Naturelle Lactobacillus Toner NIOD Non-Acid Acid Precursor 15% Tailor Skincare Renew Esho Drench Glow Lab Facial Serum HydroPeptide Power Serum The Ordinary Buffet The Ordinary Buffet + Copper Peptides 1% City Beauty Invisicrepe Body Balm Glowbiotics Gentle Probiotic Calming Lotion H20 Plus Rapids Champagne Illuminator With Champagne And Yuzu Extracts Tula Pro-Glycolic 10% Ph Resurfacing Gel Glowbiotics Probiotic Brightening + Refining Layering Solution Ren Aha Smart Renewal Body Serum Algenist Alive Prebiotic Balancing Mask Chantecaille Gold Recovery Mask Glow Lab Night Cream BIOSSANCE Squalane + Probiotic Gel Moisturizer Dr. Brandt Hydro Biotic Recovery Sleeping Mask HydroPeptide Face Lift Advanced Ultra Light Moisturiser Lumene Valo Overnight Bright Sleeping Cream Tula Kefir Replenishing Cleansing Oil Tula Multi-Spectrum Eye Renewal Serum doTERRA Hydrating Cream Tula Acne Clearing + Tone Correcting Gel Zelens Z Balance Prebiotic & Probiotic Facial Mist StriVectin Blue Rescue Clay Renewal Mask Algenist Alive Prebiotic Balancing Moisturizer Spf 15 Hygge All-In-One Mist Pacifica Coconut Probiotic Water Rehab Cream Dr. Brandt Clean Biotic Pixi Glow O2 Oxygen Mask Missha Time Revolution Night Repair New Science Activator Ampoule Mask Tula Major Glow Cooling & Brightening Hydrogel Mask Missha Time Revolution Night Repair Probio Ampoule OPHELIA Serum Foundation Missha Time Revolution Night Repair Borabit Ampoule Tula Kefir Moisture Repair Pressed Serum Missha Time Revolution Night Repair Science Activator Ampoule