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Lactococcus Ferment Lysate

Lactococcus Ferment Lysate


Official CosIng Information


Lactococcus Ferment Lysate is a fairly new probiotic ingredient that is obtained from the Gram-positive bacteria, Lactococcus lactis. The lysate is a fluid substance that is produced when you break down the cell membrane, which means it contains interesting things including cytoplasm and cell wall fragments.

According to the manufacturer, it positively influences both the speed and quality of epidermal growth that results in better barrier function and overall skin quality. To prove their point, the German manufacturer conducted several in-vitro (made in test tubes) tests examining how the treatment with Lactococcus Ferment Lysate (LFL) affects important skin proteins.

They found that gene expression influencing the proteins binding the live skin cells together (such as Occludin, Desmocollin 1 and Desmoglein 1) is stimulated by LFL, as well as the expression of enzymes (Kallikrein 5 and 7) breaking the bonds between the shedding dead skin cells. LFL also had a positive influence on epidermal growth and on the thickness of the stratum corneum (the outermost layer of the skin). Another positive finding was that LFL stimulated the production of antimicrobial peptides that play an important role in the immunocompetence of the skin cells.

As for in-vivo tests, the manufacturer only did one and that had only 5 volunteers. They did some tape stripping (exactly what it sounds, hurting the skin by stripping off the top layers) and examined skin renewal and barrier recovery. 4 days after the experiment 3% Lactococcus Ferment Lysate used twice daily resulted in thicker stratum corneum (the difference was about 2 µm) and less trans-epidermal water loss. 

Overall, Lactococcus Ferment Lysate is a promising but fairly unproven ingredient that might help with the natural skin renewal process as well as with a healthy skin barrier and skin flora.  

Products with Lactococcus Ferment Lysate

NIOD Voicemail Masque Histoire Naturelle Lactobacillus Lotion Histoire Naturelle Lactobacillus Refine Toner 1 Histoire Naturelle Lactobacillus Toner Indeed Labs noAcid Pads NIOD Non-Acid Acid Precursor 15% REN Perfect Canvas Clean Primer Tailor Skincare Renew Tula Sensitive Skin Treatment Drops Calming Vitamin B Serum DR. LEWINN'S Recoverederm Intensive Overnight Barrier Repair Balm Elemis Dynamic Resurfacing Facial Pads Esho Drench Glow Lab Facial Serum Glowbiotics Instant Refreshing Gel Hydrator Glowbiotics Probiotic Firming + Replenishing Lotion Goldfaden MD Mist Rx Daily Nutrient Facial Mist HydroPeptide Power Serum Scinic Probiotics Intense Ampoule The Ordinary Buffet The Ordinary Buffet + Copper Peptides 1% City Beauty Invisicrepe Body Balm GALLINÉE Youthful Serum Glowbiotics Gentle Probiotic Calming Lotion H20 Plus Rapids Champagne Illuminator With Champagne And Yuzu Extracts Missha A'Pieu Lactobacillus Ampoule Missha A'Pieu Lactobacillus Cream Sebamed PRO! Intensive Serum TRUELOGIE Multi-peptide anti age Tula Get Toned Pro-Glycolic 10% Resurfacing Toner Tula Signature Glow Refreshing & Brightening Face Mist Tula Signature Glow Refreshing & Brightening Face Mist Arbonne Supercalm Soothing Hydrator DONT TOUCH MY SKIN Moisturizing Cream Rich Freshly Cosmetics Blue Radiance Enzymatic Serum Germaine de capuccini B-Calm Sos Intensive Care Facial Balm Glowbiotics Instant Resurfacing Pads Glowbiotics Probiotic Brightening + Refining Layering Solution IU Nature Senandung Hujan Hydrating Toner Judith Williams Edelweiss Probiotic Face Serum Manyo Factory Bifida Biome Complex Ampoule REN Aha Smart Renewal Body Serum Algenist Alive Prebiotic Balancing Mask Arbonne Supercalm Skin Relief Serum With Tiger Grass Blend Chantecaille Gold Recovery Mask Elizabeth Arden Superstar Probiotic Cleanser - Whip To Clay Ghost Democracy Clean Lightweight Daily Face Moisturizer Glow Lab Night Cream Glowbiotics Md Hydraglow Cream Oil Sebamed Pro! Hydro Serum Tula Glow & Get It