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Careline Skin Placenta CreamIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
The famous or maybe rather infamous mineral oil. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. It is a very controversial ingredient with pros and cons and plenty of myths around it. So let us see them:
The pros of mineral oil
Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert.
It is a great emollient and moisturizer working mainly by occlusivity. Occlusivity is one of the basic mechanisms of how moisturizers work and it means that mineral oil sits on top of the skin and hinders so-called trans-epidermal water loss, i.e water evaporating out of your skin. When compared to heavy-duty plant oil, extra virgin coconut oil, the two of them were equally efficient and safe as moisturizers in treating xerosis, a skin condition connected to very dry skin.
The other thing that mineral oil is really good at is being non-irritating to the skin. The chemical composition of plant oils is more complex with many more possible allergens or irritating components, while mineral oil is simple, pure and sensitivity to it is extremely rare. If you check out the classic French pharmacy brands and their moisturizers for the most sensitive, allergy prone skin, they usually contain mineral oil. This is no coincidence.
The cons of mineral oil
The pros of mineral oil can be interpreted as cons if we look at them from another perspective. Not penetrating the skin but mostly just sitting on top of it and not containing biologically active components, like nice fatty acids and vitamins mean that mineral oil does not "nourish" the skin in the way plant oils do. Mineral oil does not give the skin any extra goodness, it is simply a non-irritating moisturizer working mainly by occlusivity.
The myths around mineral oil
Badmouthing mineral oil is a favorite sport of many, it is a cheap material and being connected to petrolatum makes it fairly easy to demonize.
While it is true that industrial grade mineral oil contains carcinogenic components (so-called polycyclic compounds), these are completely removed from cosmetic and food grade mineral oil and there is no scientific data showing that the pure, cosmetic grade version is carcinogenic.
What is more, in terms of the general health effects of mineral oils used in cosmetics, a 2017 study reviewed the data on their skin penetration and concluded that "the cosmetic use of mineral oils and waxes does not present a risk to consumers due to a lack of systemic exposure."
Another super common myth surrounding mineral oil is that it is comedogenic. A 2005 study titled "Is mineral oil comedogenic?" examined this very question and guess what happened? The study concluded that "based on the animal and human data reported, along with the AAD recommendation, it would appear reasonable to conclude that mineral oil is noncomedogenic in humans."
Overall, we feel that the scaremongering around mineral oil is not justified. For dry and super-sensitive skin types it is a great option. However, if you do not like its origin or its heavy feeling or anything else about it, avoiding it has never been easier. Mineral oil has such a bad reputation nowadays that cosmetic companies hardly dare to use it anymore.
The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.
The unique thing about petrolatum is that it is the most effective occlusive agent known today. While the occlusivity of mineral oil is in the same league as the occlusivity of plant oils, petrolatum is in a league of its own. It sits on top of the skin and hinders so-called transepidermal water loss (TEWL) like nothing else.
This comes in handy healing cracked lips or severely dry skin patches, though overdoing it (i.e. reducing TEWL by more than 40%) is not good as it can create a nice moist place for fungi and bacteria to grow.
As for petrolatum and safety, we can write here pretty much the exact same thing as we have written at mineral oil. There is no evidence whatsoever that cosmetic, USP grade petrolatum is carcinogenic. It also does not absorb into the skin but sits on top of it and that in itself greatly minimises health risks. It also has a long history of safe use, as it was first used as a skincare product more than 100 years ago, in 1872 to be precise.
It is also non-comedogenic, though its pure form is very heavy and greasy so combination and oily skin types might want to avoid it anyway.
Overall, it is the gold-standard occlusive agent known today and a tub of Vaseline comes in handy in any household to heal cracked lips or other severely dry skin patches.
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).
- It's a helper ingredient that improves the freeze-thaw stability of products
- It's also a solvent, humectant and to some extent a penetration enhancer
- It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
We don't have description for this ingredient yet.
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
We don't have description for this ingredient yet.
It’s a little helper ingredient that helps to set the pH of a cosmetic formulation to be just right. It’s very alkaline (you know the opposite of being very acidic): a 1% solution has a pH of around 10.
It does not have the very best safety reputation but in general, you do not have to worry about it.
What is true is that if a product contains so-called N-nitrogenating agents (e.g.: preservatives like 2-Bromo-2-Nitropropane-1,3-Diol, 5-Bromo-5-Nitro- 1,3-Dioxane or sodium nitrate - so look out for things with nitro, nitra in the name) that together with TEA can form some not nice carcinogenic stuff (that is called nitrosamines). But with proper formulation that does not happen, TEA in itself is not a bad guy.
But let’s assume a bad combination of ingredients were used and the nitrosamines formed. :( Even in that case you are probably fine because as far as we know it cannot penetrate the skin.
But to be on the safe side, if you see Triethanolamine in an INCI and also something with nitra, nitro in the name of it just skip the product, that cannot hurt.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
An antimicrobial preservative that helps your products not to go wrong too quickly. It works especially well against bacteria, specifically gram-negative species, yeast, and mold.
Somewhat controversial, it belongs to an infamous family of formaldehyde-releasers. That is, it slowly breaks down to form formaldehyde when it is added to a formula. We have written more about formaldehyde-releasing preservatives and the concerns around them at Dmdm Hydantoin, but do not get too scared, those are more theories than proven facts.
As for Diazolidinyl Urea itself, a study from 1990 writes that at concentrations up to 0.4%, it was a mild cumulative skin irritant, but the CIR (Cosmetic Ingredient Review) reviewed it in 2006 and found that, in concentrations of <0.5%, it is safe as used, as the amount of formaldehyde released will be smaller than the recommended limit (of less than 0.2%).
All in all, it is up to your personal decision and skin sensitivity.
The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon.
Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing that when exposed to sunlight, MP treated skin cells suffered more harm than non-MP treated skin cells. The study was not done with real people on real skin but still - using a good sunscreen next to MP containing products is a good idea. (Well, in fact using a sunscreen is always a good idea. :))
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
A very common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon.
The oil coming from the pulp of one of the most nutritious fruits in the world, the avocado. It's loaded with the nourishing and moisturizing fatty acid, oleic (70%) and contains some others including palmitic (10%) and linoleic acid (8%). It also contains a bunch of minerals and vitamins A, E and D.
Avocado oil has extraordinary skin penetration abilities and can nourish different skin layers. It's a very rich, highly moisturizing emollient oil that makes the skin smooth and nourished. Thanks to its vitamin E content it also has some antioxidant properties. As a high-oleic plant oil, it is recommended for dry skin.
A goodie plant oil coming from the polyphenol-rich seeds of the grape. It's a light emollient oil that makes your skin feel smooth and nice and also contains a bunch of good-for-the-skin stuff. It's a great source of antioxidant polyphenols, barrier repair fatty acid linoleic acid (about 55-77%, while oleic acid is about 12-27%) and antioxidant, skin-protectant vitamin E.
Jojoba is a drought resistant evergreen shrub native to South-western North America. It's known and grown for jojoba oil, the golden yellow liquid coming from the seeds (about 50% of the weight of the seeds will be oil).
At first glance, it seems like your average emollient plant oil: it looks like an oil and it's nourishing and moisturizing to the skin but if we dig a bit deeper, it turns out that jojoba oil is really special and unique: technically - or rather chemically - it's not an oil but a wax ester (and calling it an oil is kind of sloppy).
So what the heck is a wax ester and why is that important anyway? Well, to understand what a wax ester is, you first have to know that oils are chemically triglycerides: one glycerin + three fatty acids attached to it. The fatty acids attached to the glycerin vary and thus we have many kinds of oils, but they are all triglycerides. Mother Nature created triglycerides to be easily hydrolyzed (be broken down to a glycerin + 3 fatty acid molecules) and oxidized (the fatty acid is broken down into small parts) - this happens basically when we eat fats or oils and our body generates energy from it.
Mother Nature also created wax esters but for a totally different purpose. Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Wax esters are on the outer surface of several plant leaves to give them environmental protection. 25-30% of human sebum is also wax esters to give us people environmental protection.
So being a wax ester results in a couple of unique properties: First, jojoba oil is extremely stable. Like crazy stable. Even if you heat it to 370 C (698 F) for 96 hours, it does not budge. (Many plant oils tend to go off pretty quickly). If you have some pure jojoba oil at home, you should be fine using it for years.
Second, jojoba oil is the most similar to human sebum (both being wax esters), and the two are completely miscible. Acne.org has this not fully proven theory that thanks to this, jojoba might be able to "trick" the skin into thinking it has already produced enough sebum, so it might have "skin balancing" properties for oily skin.
Third, jojoba oil moisturizes the skin through a unique dual action: on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer; on the other hand, it absorbs into the skin through pores and hair follicles then diffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple.
On balance, the point is this: in contrast to real plant oils, wax esters were designed by Mother Nature to stay on the surface and form a protective, moisturizing barrier and jojoba oil being a wax ester is uniquely excellent at doing that.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.
To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so-called peptide bonds. These bonds can be broken up when a water molecule is added and the resulting thing is a mix of shorter length amino acids, also called peptides. So Hydrolyzed Collagen is not really collagen, it is rather an undefined and varying mix of largish peptides. Based on a manufacturer's data, the whole, soluble collagen has an average molecular weight of 300 000 Da, while this chopped up mixture has an average MW of 12 000 Da (still pretty big).
The main thing of these largish peptides is to act as water-binding agents, and to make the skin nice and smooth (aka emollient). Hydrolyzed Collagen is also often used in cleansers as it can make harsh surfactants milder and in hair conditioners as it improves the flexibility and manageability of hair.
If you wanna know more about collagen in cosmetics, we have a shiny explanation about soluble collagen here >>
A chemically chopped up version of protein coming from bovine placenta (yes, it is an animal-derived ingredient). Proteins are long amino acid chains, so when you chop them up you get peptides (short amino-acid chains) and amino acids, nice molecules that are known as the "building blocks of life".
In general, amino acids, peptides, and proteins are moisturizing, nourishing and regenerating ingredients when you smear them on your face, so is probably Hydrolyzed Placental Protein. According to manufacturer's information, it also works as a film forming, protecting and restructuring agent. Due to its high amino acid content, it improves surface hydration and elasticity and due to its larger peptide and protein molecules, it forms a nice film on the skin that reduces trans-epidermal-water-loss (i.e. hinders water evaporating out of the top layers of the skin). These effects help to maintain the water content of the skin cells and result in a healthy skin & nice complexion.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.
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| what‑it‑does | solvent |
| what‑it‑does | emollient | solvent |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | emollient |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 0, 2-3 |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 0 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1-2 |
| what‑it‑does | emollient | emulsifying | surfactant/cleansing |
| irritancy, com. | 0, 0-1 |
| what‑it‑does | buffering |
| irritancy, com. | 0, 2 |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | preservative |
| what‑it‑does | preservative |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient |
| what‑it‑does | preservative | perfuming |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant | emollient |
| irritancy, com. | 0, 0-3 |
| what‑it‑does | antioxidant | emollient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | perfuming |
| what‑it‑does | emollient | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | emollient | moisturizer/humectant |