0.3% Retinol Complex Serum With Peptides
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First Aid Beauty 0.3% Retinol Complex Serum With PeptidesIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Retinyl Propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare". You can read the who's who here but the TL;DR version is that tretinoin is the king himself (the FDA-proven anti-aging active molecule), retinol is like Prince George (two conversion steps needed to be active) and Retinyl Palmitate is like Prince Charlotte (George's little sister), 3 steps away from the throne.
Similar to Retinyl Palmitate, Retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together. This puts our molecule in the place of little Princess Charlotte on the family tree, quite far away from the throne. However, not all retinol ester molecules are made equal when it comes to being transformed and being effective on the skin.
As Dr. Fulton (the scientist behind both Retin-A and RP) puts it in his patent paper, "Other esters of vitamin A obtained from, for example, palmitic acid and acetic acid do not have the therapeutic advantages found with vitamin A propionate ..... Presumably, the [Retinyl Palmitate] molecule is so large, it is not able to transdermally reach the necessary part of the skin for activity. Similarly, vitamin A acetate is too small molecularly and therefore easily recrystallizes from any solution.....vitamin A propionate is the appropriate molecular weight and configuration to both remain in a stable solution and to be transdermally delivered to a site where it is active." So while the effectiveness of other retinol esters is highly questionable, Retinyl Propionate seems to be the most effective retinol ester molecule, and it "unexpectedly provides all the benefits of vitamin A acid but minimizes the negative side effects", at least according to Dr. Fulton, the inventor of the molecule.
We know what you are thinking! This sounds great and all, but what about some proof? Some backup data not from the inventor himself? We looked into it and found three studies working with Retinyl Propionate.
In a 2007 study by Dr. Draelos, she references a 12-week, double-blind, placebo-controlled clinical trial that compared the effectiveness of 0.15% retinol with 0.3% Retinyl Propionate. Both actives were effective in reducing the appearance of facial wrinkles and hyperpigmentation and the 0.3% RP worked a bit better.
Another research that was done by Procter & Gamble combined multiple anti-aging actives including niacinamide, peptides and 0.3% of Retinyl Propionate and they compared this regimen with a 0.02% tretinoin regimen. They found that the cosmetic regimen was tolerated better, worked faster and gave comparable results. All this sounds very promising for RP, however, it is hard to know how much the other actives contributed to the positive results.
Last, but not least there is a study from 1998 that tested a 0.15% Retinyl Propionate cream and after 24 weeks found no statistically significant difference between the effects of the retinyl propionate cream and the placebo preparation for any of the clinical parameters of skin photoaging. However, after 48 weeks, the 0.15% RP worked wonders for actinic keratoses, a rough, scaly patch caused by UV damage (its name contains actinic, but it is not acne, has nothing to do with it (!)).
So, it seems that the minimum effective dose of Retinyl Propionate is larger than 0.15% which is not surprising given that it has to do three conversion steps to reach the active form, retinoic acid. But 0.3% RP (or more, obvs) seems to be an effective dose, and even though the proof is not as solid as it is for retinol itself, if you are looking for a more gentle alternative, or if you are in the mood for experimentation, Retinyl Propionate looks like a noteworthy alternative and the most promising option among retinol esters.
- Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
- It has to be converted in the skin to retinoic acid to work its magic
- Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
- A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
- It makes skin less wrinkled, smoother, firmer and tighter
- It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
- Possible side effects and irritation are also much less than with retinoic acid
- Do not use whilst pregnant
We don't have description for this ingredient yet.
A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent.
A thick, high molecular weight silicone that is usually diluted in another, lighter silicone fluid (like dimethicone or cyclopentasiloxane). The dimethiconol containing silicone blends leave a silky smooth, non-greasy film on the skin.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
This long-named, polymer molecule (big molecule from repeated subunits) is a helper ingredient that's good at emulsifying and stabilizing oils into water-based formulas. It also acts as a thickening and gelling agent that creates nice, non-sticky and supple textures. It works over a very wide pH range (3-12) and can be used to thicken up low-ph formulas, such as exfoliants. Its recommended used range is 0.3-3%.
A light, velvety, unique skin feel liquid that is a good solvent and also makes the skin feel nice and smooth (aka emollient). It's often used in makeup products mixed with silicones to give shine and slip to the product. It's also great for cleansing dirt and oil from the skin as well as for taking off make-up.
We don't have description for this ingredient yet.
A super versatile and common mineral powder that comes in different particle sizes. It is a multi-tasker used to improve skin feel, increase product slip, give the product light-reflecting properties, enhance skin adhesion or serve as an anti-caking agent.
It is also the most commonly used "base" material for layered composite pigments such as pearl-effect pigments. In this case, mica is coated with one or more metal oxides (most commonly titanium dioxide) to achieve pearl effect via the physical phenomenon known as interference.
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula.
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved.
It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula.
A little helper ingredient that is used to adjust the pH of the product. It also helps to keep products stay nice longer by neutralizing the metal ions in the formula (they usually come from water).
A handy helper ingredient that helps water and oil to mix nicely together, aka emulsifier. It is especially recommended for protective, baby care and general purpose emollient creams.
It also helps to disperse insoluble particles (think color pigments or zinc/titanium dioxide sunscreen) nice and even in cosmetic formulas.
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.
There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.
As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%), it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
Ci 77891 is the color code of titanium dioxide. It's a white pigment with great color consistency and dispersibility.
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| what‑it‑does | solvent |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | emollient |
| what‑it‑does | antioxidant |
| what‑it‑does | emollient |
| what‑it‑does | buffering |
| what‑it‑does | viscosity controlling |
| what‑it‑does | emollient | moisturizer/humectant |
| what‑it‑does | chelating |
| what‑it‑does | viscosity controlling |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 4, 5 |
| what‑it‑does | colorant |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 0, 0 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | solvent | moisturizer/humectant |
| what‑it‑does | chelating | buffering |
| what‑it‑does | emulsifying |
| irritancy, com. | 0, 1-2 |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | preservative |
| what‑it‑does | preservative |
| what‑it‑does | colorant |
| irritancy, com. | 0, 0 |