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DermDoc Niacinamide And Sodium Hyaluronate Serum

Niacinamide And Sodium Hyaluronate Serum

Moisturising face serum with Niacinamide & Sodium Hyaluronate.
Uploaded by: thrishamirzashaik on

DermDoc Niacinamide And Sodium Hyaluronate Serum
Ingredients explained

Niacinamide - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

It's a special "cross-linked" from of IT-moisturizer, hyaluronic acid (HA). Cross-linked means that "normal" HA pieces (1-2 million Da molecular weight) are chemically bound togeather to create a big, "infinite" mesh.

The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. This water filled crosslinked HA gel forms a smooth film on the skin and continuously delivers the bound water, so it gives long-term moisturizing benefits.

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Btw, crosslinking HA was developed for dermal fillers (as crosslinking helps their longevity), and this guy is the topical version of FDA approved dermal filler called Hylan B gel. Smearing crosslinked version all over ourselves is a newish thing, and incoming evidence so far suggests that it's a great idea, even better than normal HA. 

A very recent, 2016 research article compared the topical moisturizing effect of crosslinked HA (not Hylan B gel specifically, but something called Resilient HA or RHA), HMW-HA and LMW-HA and found that "TEWL (that is trans-epidermal water loss, the water that evaporates from the skin) was reduced by 27.8% with RHA, and by 15.6% with HMW HA, but increased by 55.5% with LMW HA." (You can read much more about HMW and LMW HA here in the geeky details section.)

All in all, we think Sodium Hyaluronate Crosspolymer is an awesome version of HA, probably superior to traditional versions, so be happy to spot it on the ingredient list. 

We don't have description for this ingredient yet.

This is a trade name with the following INCI listing: Xylitylglucoside, Anhydroxylitol, Xylitol
What-it-does: moisturizer/humectant

The main part of a moisturizing complex called Aquaxyl. Comes from two water-binding plant sugars, glucose and xylitol. According to the manufacturer, Aquaxyl is close to a magic moisturizer that not only simply moisturizes, but can "harmonize the skin's hydrous flow".

This means that on the one side it can optimize water reserves by increasing important NMFs (natural moisturizing factors - things that are naturally in the skin and help to keep it hydrated) - like hyaluronic acid and chondroitin sulfate -  in the skin. On the other side, it also limits water loss by improving the skin barrier with increased lipid (ceramides and cholesterol) and protein synthesis. 

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In vivo (made on real people) tests show that 3% Aquaxyl not only increases the water content of the outer layer instantly and in the long run but it also visibly improves cracked, dry skin and smoothes the skin surface after a month of treatment.

The hydrating effect of Aquaxyl was also examined in a comparative study in the Journal of cosmetic dermatology. The hydrogel with 4% Aquaxyl performed as well as the well-known moisturizer, urea and somewhat better than the formula containing NMF components or hydrating plant extract called Imperata Cylindrica

All in all,  Aquaxyl is a goodie and if you have dehydrated, dry skin it's something to look at. 

What-it-does: moisturizer/humectant

A sugar derived moisturizer that's part of a moisturizing trio called Aquaxyl. You can read more about its magic properties at xylitylglucoside

Xylitol - goodie
What-it-does: moisturizer/humectant

A type of sugar that's part of a moisturizing trio called Aquaxyl. You can read more about its magic properties at xylitylglucoside

Also-called: Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

The neutralized form of gluconic acid. It's a great ingredient to neutralize metal (especially iron and copper) ions in a cosmetic product. This helps to prevent discoloration of the formula over time or rancidity of cosmetic oils. It can also be a pH regulator and a humectant (helps skin to cling onto water).

It's also used in oral care products where it reduces the bitterness of other ingredients. And it's natural, both Ecocert and Cosmos approved. (source: manufacturer info)

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

Also-called: Part of Olivem 1000 | What-it-does: emulsifying

An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000. 

Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles as an active ingredient with significant moisturizing, barrier-repairing and soothing properties.

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It also helps to deliver water-soluble actives such as caffeine more effectively, and can even boost SPF in sunscreen formulas. Its typical use level is 1-5% and has wide compatibility with other actives and oils.

Overall, a real multi-tasker with nice sensorial properties. No wonder it is so popular.

Also-called: Part of Olivem 1000 | What-it-does: emulsifying

An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>

Also-called: lye | What-it-does: buffering

The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right. 

For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.  

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BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.

Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

Perfume - icky
Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face than fragrance is not your best friend - no way to know what’s really in it.  

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Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!). 

You may also want to take a look at...

what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
what‑it‑does skin-identical ingredient | antioxidant | moisturizer/humectant
A special, "cross-linked" from of hyaluronic acid (HA). Claimed to have five times the water-binding capacity of normal HA, also acts as an antioxidant and gives skin long-term moisture. [more]
what‑it‑does moisturizer/humectant
The main part of a sugar based moisturizing complex called Aquaxyl. Can "harmonize the skin's hydrous flow" by optimizing water reserves and limiting water loss. [more]
what‑it‑does moisturizer/humectant
A sugar derived moisturizer that's part of a moisturizing trio called Aquaxyl. You can read more about its magic properties at xylitylglucoside.  [more]
what‑it‑does moisturizer/humectant
A type of sugar that's part of a moisturizing trio called Aquaxyl. You can read more about its magic properties at xylitylglucoside.  [more]
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does chelating | moisturizer/humectant
The neutralized form of gluconic acid. It's a great ingredient to neutralize metal (especially iron and copper) ions in a cosmetic product. This helps to prevent discoloration of the formula over time or rancidity of cosmetic oils. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does viscosity controlling | emulsifying | surfactant/cleansing
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does emulsifying
Part of Olivem 1000, a natural emulsifier duo that is known for forming biomimetic liquid crystal structures. It doubles as an active ingredient with barrier repairing and soothing properties. [more]
what‑it‑does emulsifying
An ester coming from sorbitol and the fatty acids of olive oil. It often comes to the formula coupled with Cetearyl Olivate and the two together help water and oil to blend (emulsifier). It's a natural and Ecocert approved duo.
what‑it‑does buffering
Lye - A solid white stuff that’s very alkaline and used in small amount to adjust the pH of the product.  [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]