ZENMED

Nutrient Boost Spray

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

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The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though  oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.

Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically. 

It's not only soothing but it' also skin-softening and protecting and can promote wound healing.

A medicinal plant with analgesic (painkilling) and anti-inflammatory magic properties. It contains allantoin and rosmarinic acid that are probably responsible for its soothing power. It's often used in the field of sports for treating bruises or sprains.

The questionable side of comfrey (that prevented us from giving it a goodie rating) is that it also contains pyrrolizidine alkaloids (PA). That guy has some proven toxic effect so for example in Germany the permissibale dose of PA is 100 μg/day and if the dose is between 10-100 μg/day the treatment is limited to 4-6 weeks per year.

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PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium salt form of PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. 

We don't have description for this ingredient yet.

Chamomile probably needs no introduction as it's one of the most widely used medicinal herbs. You probably drink it regularly as a nice, calming cup of tea and it's also a regular on skincare ingredient lists.

Cosmetic companies use it mainly for its anti-inflammatory properties. It contains the terpenoids chamazulene and bisabolol both of which show great anti-inflammatory action in animal studies. On top of that chamomile also has some antioxidant activity (thanks to some other active ingredients called matricine, apigenin and luteolin).  

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We don't have description for this ingredient yet.

In general, flower waters are diluted versions of essential oils meaning they contain pretty much the same components but in much-reduced concentrations. So lavender flower water is a highly diluted version of lavender essential oil. According to manufacturer claims, it's traditionally used as bath water or wash water and might be useful for acne-prone or oily skin thanks to lavender's antibacterial properties.

We wrote in detail about lavender essential oil and why we prefer it not to have in skincare products (in short, it not only contains fragrant components but research shows it might be cytotoxic even at low concentrations) so we would also be cautious with the lavender water. It's much more diluted - so less effect and less side effect - but why risk it? 

A form of skincare superstar, Vitamin C. If you do not know, what the big deal about Vitamin C is, click here and read all about it, we will wait here for you. 

So now you know that pure vitamin C (aka ascorbic acid, AA) is really unstable and hard to formulate so the cosmetics industry is coming up with a bunch of derivatives to solve the problem and Magnesium Ascorbyl Phosphate (or MAP) is one of them.  

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• Primary fat-soluble antioxidant in our skin
• Significant photoprotection against UVB rays
• Vit C + Vit E work in synergy and provide great photoprotection
• Has emollient properties
• Easy to formulate, stable and relatively inexpensive

• It’s naturally in our skin and behaves there like a sponge
• It can bind up to 1000 times its own weight in water
• It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
• High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
• Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
• Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
• Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule

This totally unpronounceable ingredient (let’s take a shortcut: MCI) is a super effective preservative with both antibacterial and antifungal effects that works at very low concentrations. 

The bad news with it though is that it can sensitize the skin easily (it’s a so-called non-fragrance allergen). It’s not permitted to be used alone, but only with its BFF, methylisothiazolinone (MI), another icky preservative. Together they have a broad spectrum antimicrobial effect but are permitted to be used only in rinse-off products (under 0.0015%).

As you may guess, if something is only recommended in products that you rinse off (cleansers and shampoos), then it’s probably not the best ingredient for the skin.

Methylisothiazolinone (MI) is a preservative that' super efficient against bacteria at surprisingly low concentrations. The problem with it though is that it can also sensitize and irritate the skin quite easily when it comes in leave-on formulas.

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