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Obagi Clenziderm M.d.® Therapeutic LotionIngredients explained
The gold standard topical ingredient in treating acne. There is no miracle cure for acne (we do really wish for one, *sigh*), but Benzoyl Peroxide (BP) is probably the closest thing we have. But, as usual, big effects come with big side effects, so we think BP is best used as a last resort (at least, in the topical treatment field).
The good thing about BP is that it is amazingly effective against inflammatory-type acne. Not so much against blackheads or whiteheads, but against acne that is caused by the evil bacteria called Propionibacterium acnes (and that is most types of acne). Apart from being antibacterial, it is also anti-inflammatory, keratolytic and wound-healing, all of which are properties that make it so darn effective against spots.
Another big pro of BP is that there is no bacterial resistance to it, meaning if it works once it will continue to work. Antibiotics are also a common way to treat acne, but antibiotic-resistant P. acnes are increasing worldwide. BP will probably help you even if antibiotics have stopped working, and the two are also often combined for a more complex acne therapy. Btw, BP plays nice not only with antibiotics but also with retinoids.
The side-effects part? BP works its antibacterial magic by being a powerful oxidizing agent, meaning it is a pro-oxidant. As in the opposite of an antioxidant. BP literally generates evil ROS (reactive oxygen species) in the skin that kills P. acnes but also harms the surrounding skin cells. Ongoing BP-use ages your skin, which is why, we say, use it as a last resort. If you do use BP, please also use a good sunscreen and a good antioxidant serum to apologise to your skin (btw, these things are useful in any case). Use the BP treatment at night and the antioxidant serum in the morning so that they do not cancel each other out.
Another side effect of BP is that it can be very skin drying. BP is an example where more is not better. In fact, it is equally effective at concentrations of 2.5, 5.0 and 10%, but the higher the concentration the more irritating and drying side effects occur. So using BP at 2.5% percent is the ideal amount. Another side effect which is good to know is that BP can bleach bedsheets and clothes. Be careful with your expensive satin bedsheets.
Overall, Benzoyl Peroxide is a uniquely effective topical acne treatment, but it comes at a price. Use it as a last resort and for good measure (and with plenty of moisturizers, sunscreen, and antioxidant serum).
A common fragrance ingredient that has a faint sweet balsamic smell. It can also be a solvent and can fight against microbes and insects very well.
It's one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. Best to avoid if your skin is sensitive.
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.
There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.
As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%), it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.
A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel.
A little helper ingredient that can boost the performance and enhance the delivery of active ingredients in a formula. It can penetrate deep layers of the skin helping actives to do the same.
It's especially useful to help active ingredients for self-tanning (DHA), anti-acne or skin-whitening to penetrate deeper and work better.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
This long-named, polymer molecule (big molecule from repeated subunits) is a helper ingredient that's good at emulsifying and stabilizing oils into water-based formulas. It also acts as a thickening and gelling agent that creates nice, non-sticky and supple textures. It works over a very wide pH range (3-12) and can be used to thicken up low-ph formulas, such as exfoliants. Its recommended used range is 0.3-3%.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
- It's a helper ingredient that improves the freeze-thaw stability of products
- It's also a solvent, humectant and to some extent a penetration enhancer
- It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
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| what‑it‑does | anti-acne |
| what‑it‑does | solvent | perfuming | antimicrobial/antibacterial |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | emollient | solvent |
| what‑it‑does | solvent | viscosity controlling |
| what‑it‑does | chelating |
| what‑it‑does | viscosity controlling |
| what‑it‑does | preservative |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 0 |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | solvent |