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dermaheal HlIngredients explained
Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. This guy consists of 70 amino acids and, similar to EGF, it is also claimed to stimulate cell proliferation and wound healing. There is also a study that indicates EGF and IGF1 work in synergy to promote keratinocyte (skin cell) proliferation.
The topic of Growth Factors in skincare is complex and controversial. If you are new to it, read our shiny explanation on EGF to get a (hopefully) balanced impression about the pros and cons.
Sh-Polypeptide-1 is a cell signaling protein also called Basic Fibroblast Growth Factor and is twin sister to Acidic Fibroblast Growth Factor. We can write here pretty much the same things as we did on aFGF: it is a mitogenic (= stimulates cell proliferation) ingredient that stimulates fibroblast cell growth and proliferation. According to manufacturer info, it also stimulates the synthesis of collagen and other extracellular-matrix (the gooey stuff between cells) components.
Growth Factors and skincare is a big, complicated and controversial topic, so if you wanna know more, we have a more detailed explanation on Epidermal Growth Factor, the most common one used in skincare.
Sh-Polypeptide-9 is a cell signaling protein also called Vascular Endothelial Growth Factor. As its name suggests, its main function is to stimulate the formation of blood vessels. As to what it does in cosmetic products, we found manufacturers info claiming that it plays a role in supplying fibroblast cells (VIP skin cells that make collagen) with nutrients, in the growth and migration of cells and in wound healing.
It usually comes to the formula as part of a Growth Factor mix trade named BIO-Placenta, that combines EGF, IGF-1, FGF1, FGF2 and this guy to form a synergistic growth factor cocktail. BIO Placenta is claimed to do pretty much everything you would want from an anti-aging active including anti-wrinkle, skin rejuvenation, elasticity enhancement, moisturizing and cell vitalization properties.
This all sounds great and Growth Factors are for sure potent cell signaling molecules, but the use of them in cosmetic products is somewhat controversial, so if you are new to the topic, read our explanation at EGF to get a (hopefully) balanced view.
- GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
- It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
- It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
- It has significant anti-inflammatory and antioxidant effect
- There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
- It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
- There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
- GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
- It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
- It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
- It has significant anti-inflammatory and antioxidant effect
- There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
- It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
- There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
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