Avene Xeracalm A.D. Lipid-Replenishing Cream
Avene

Xeracalm A.D. Lipid-Replenishing Cream

This lipid-replenishing cream directly targets itching, redness and irritation for skin prone to atopic dermatitis and eczema. Formulated without any preservatives, parabens or fragrances, its patented delivery system keeps the cream completely sterile and safe for its entire use. Suitable for infants, children and adults.
Uploaded by: mhlee3721 on 12/10/2018

Ingredients overview

Avène Thermal Spring Water, Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Mineral Oil
what‑it‑does emollient
A clear, oily liquid that comes from refining crude oil. Even though it is a highly controversial ingredient, the scientific consensus is that it is a safe, non-irritating and effective emollient and moisturizer working mainly by occlusivity. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Oenothera Biennis Oil
what‑it‑does soothing | emollient
irritancy, com. 2 3
An emollient plant oil loaded with nourishing and moisturizing fatty acids. It's a very rich source of linoleic acid (66-76%), and also contains the soothing and healing superstar fatty acid, gamma-linoleic acid. [more]
,
Caprylic/Capric Triglyceride
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
,
Cetearyl Glucoside
what‑it‑does emulsifying | surfactant/cleansing
A sugar based emulsifier that's especially great for low viscosity lotions or even sprays. [more]
,
Aquaphilus Dolomiae Extract, Arginine
what‑it‑does skin-identical ingredient
An amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor and might also help to speed up wound healing.  [more]
, [more]
Carbomer
what‑it‑does viscosity controlling
It’s a handy white powder that magically converts a liquid into a nice gel formula. [more]
,
Evening Primrose Oil/Palm Oil Aminopropanediol Esters, Glycine
what‑it‑does skin-identical ingredient
An amino acid (the building blocks of skin proteins, like collagen) that hydrates the skin and might help wound healing and improve wrinkles. [more]
,
Sodium Hydroxide
what‑it‑does buffering
Lye - A solid white stuff that’s very alkaline and used in small amount to adjust the pH of the product.  [more]
,
Tocopherol
what‑it‑does antioxidant
irritancy, com. 2 2
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
,
Water
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
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Highlights

Key Ingredients

Antioxidant: Tocopherol
what‑it‑does antioxidant
irritancy, com. 2 2
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
Skin-identical ingredient: Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Arginine
what‑it‑does skin-identical ingredient
An amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor and might also help to speed up wound healing.  [more]
,
Glycine
what‑it‑does skin-identical ingredient
An amino acid (the building blocks of skin proteins, like collagen) that hydrates the skin and might help wound healing and improve wrinkles. [more]
Soothing: Oenothera Biennis Oil
what‑it‑does soothing | emollient
irritancy, com. 2 3
An emollient plant oil loaded with nourishing and moisturizing fatty acids. It's a very rich source of linoleic acid (66-76%), and also contains the soothing and healing superstar fatty acid, gamma-linoleic acid. [more]

Show all ingredients by function

Other Ingredients

Buffering: Sodium Hydroxide
what‑it‑does buffering
Lye - A solid white stuff that’s very alkaline and used in small amount to adjust the pH of the product.  [more]
Emollient: Mineral Oil
what‑it‑does emollient
A clear, oily liquid that comes from refining crude oil. Even though it is a highly controversial ingredient, the scientific consensus is that it is a safe, non-irritating and effective emollient and moisturizer working mainly by occlusivity. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Oenothera Biennis Oil
what‑it‑does soothing | emollient
irritancy, com. 2 3
An emollient plant oil loaded with nourishing and moisturizing fatty acids. It's a very rich source of linoleic acid (66-76%), and also contains the soothing and healing superstar fatty acid, gamma-linoleic acid. [more]
,
Caprylic/Capric Triglyceride
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
Emulsifying: Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Cetearyl Glucoside
what‑it‑does emulsifying | surfactant/cleansing
A sugar based emulsifier that's especially great for low viscosity lotions or even sprays. [more]
Moisturizer/humectant: Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
Solvent: Water
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
Surfactant/cleansing: Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Cetearyl Glucoside
what‑it‑does emulsifying | surfactant/cleansing
A sugar based emulsifier that's especially great for low viscosity lotions or even sprays. [more]
Viscosity controlling: Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Carbomer
what‑it‑does viscosity controlling
It’s a handy white powder that magically converts a liquid into a nice gel formula. [more]

Ingredients explained

We don't have description for this ingredient yet.

Glycerin - goodie
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • Super common, used for more than 50 years
  • Not only a simple moisturizer but plays an important role in keeping the stuff between our skin cells healthy
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Also-called: Mineral Oil | What-it-does: emollient

The famous or maybe rather infamous mineral oil. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. It is a very controversial ingredient with pros and cons and plenty of myths around it. So let us see them:  

The pros of mineral oil
Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert.

Expand to read more

It is a great emollient and moisturizer working mainly by occlusivity. Occlusivity is one of the basic mechanisms of how moisturizers work and it means that mineral oil sits on top of the skin and hinders so-called trans-epidermal water loss, i.e water evaporating out of your skin. When compared to heavy-duty plant oil, extra virgin coconut oil, the two of them were equally efficient and safe as moisturizers in treating xerosis, a skin condition connected to very dry skin.

The other thing that mineral oil is really good at is being non-irritating to the skin. The chemical composition of plant oils is more complex with many more possible allergens or irritating components, while mineral oil is simple, pure and sensitivity to it is extremely rare. If you check out the classic French pharmacy brands and their moisturizers for the most sensitive, allergy prone skin, they usually contain mineral oil. This is no coincidence. 

The cons of mineral oil
The pros of mineral oil can be interpreted as cons if we look at them from another perspective. Not penetrating the skin but mostly just sitting on top of it and not containing biologically active components, like nice fatty acids and vitamins mean that mineral oil does not "nourish" the skin in the way plant oils do. Mineral oil does not give the skin any extra goodness, it is simply a non-irritating moisturizer working mainly by occlusivity, and nothing more. 

The myths around mineral oil
Bad mouthing mineral oil is a favorite sport of many, it is a cheap material and being connected to petrolatum makes is fairly easy to demonize. 

While it is true that industrial grade mineral oil contains carcinogenic components (so-called polycyclic compounds), these are completely removed from cosmetic and food grade mineral oil and there is no scientific data showing that the pure, cosmetic grade version is carcinogenic.

What is more, in terms of the general health effects of mineral oils used in cosmetics, a 2017 study reviewed the data on their skin penetration and concluded that "the cosmetic use of mineral oils and waxes does not present a risk to consumers due to a lack of systemic exposure."  

Another super common myth surrounding mineral oil is that it is comedogenic. A 2005 study titled "Is mineral oil comedogenic?" examined this very question and guess what happened? The study concluded that  "based on the animal and human data reported, along with the AAD recommendation, it would appear reasonable to conclude that mineral oil is noncomedogenic in humans.

Overall, we feel that the scaremongering around mineral oil is not justified. For dry and super-sensitive skin types it is a great option. However, if you do not like its origin or its heavy feeling or anything else about it, avoiding it has never been easier. Mineral oil has such a bad reputation nowadays that cosmetic companies hardly dare to use it anymore. 

What-it-does: emollient, emulsifying, viscosity controlling, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

A super common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products

It’s a so-called fatty alcohol (a mix of cetyl and stearyl alcohol - other two emollient fatty alcohols).  Though alcohol is in its name, its properties are totally different from the properties of “normal” alcohol, or denat. alcohol. It’s not drying and not irritating and totally ok for the skin.

Also-called: Evening Primrose Oil, EPO | What-it-does: soothing, emollient | Irritancy: 2 | Comedogenicity: 3

The oil coming from the seeds of the nice, little, yellow-flowered plant called Evening Primrose. Similar to other plant oils, it's loaded with nourishing and moisturizing fatty acids. It's a very rich source of linoleic acid (66-76%), and also contains the soothing and healing superstar fatty acid, gamma-linolenic acid (aka GLA, 7-12%) (Btw, the richest known source of GLA is the borage oil, but evening primrose still counts as a very good source of it). It also contains oleic acid, but not too much around 6-15%.

Since the 1980's, EPO is a well-known food supplement and there are quite a lot of studies examining what happens if you take it orally. It seems to be helpful with a bunch of  things: atopic dermatitis, dry eyes, brittle nails, sunburn and even acne.

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As for the skin, it's a great hydrating plant oil, that can also reduce inflammation and irritation. It's a superb healing agent that can truly help dry skin, not just on the surface by covering it (and not letting water to evaporate) but by initiating structural changes within the skin. If that's not enough, it also helps skin cell regeneration

All in all, a real goodie especially for dry, easily irritated skin.

What-it-does: emollient

A very common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, and it’s also easy to formulate with. No wonder it’s popular. 

A sugar based emulsifier that's especially great for low viscosity lotions or even sprays. It's effective in small amounts, only 1-1.5% is needed to form an emulsion. The resulting cream or lotion has great cosmetic properties with good spreadability and an enhanced soft skin feel. 

We don't have description for this ingredient yet.

Arginine - goodie

A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing

Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former.  Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs

What-it-does: viscosity controlling

It’s a handy white powder that magically converts a product into a nice gel formula. If you see gel in the name of a moisturiser type thing, chances are carbomer will be in the ingredient list. 

It’s not too common, but sometimes there is also a number after it. The reason for it is that carbomer in itself actually refers to a group of stuff and the number shows the weight and type of the molecule. 

We don't have description for this ingredient yet.

Glycine - goodie

A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more. 

According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles

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BTW, it's also a building block of a bunch of important and famous peptides, including copper-tripeptide-1, palmitoyl tripeptide-1 or palmitoyl hexapeptide-12.

Also-called: lye | What-it-does: buffering

The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right. 

For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.  

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BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.

Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.

Tocopherol - superstar
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 2 | Comedogenicity: 2
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

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