Oxy-r Peptides
Highlights
Key Ingredients
Other Ingredients
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| Ingredient name | what-it-does | irr., com. | ID-Rating |
|---|---|---|---|
| Aqua (Water) | solvent | ||
| Butylene Glycol | moisturizer/humectant, solvent | 0, 1 | |
| Artocarpus Lakoocha Wood Extract | antimicrobial/antibacterial, antioxidant, skin brightening | ||
| Hydroxyresveratrol | skin brightening | ||
| Gluconolactone | exfoliant, chelating | superstar | |
| Acetyl Glycyl Beta-Alanine | skin brightening | goodie | |
| Glycerin | skin-identical ingredient, moisturizer/humectant | 0, 0 | superstar |
| Lactic Acid | exfoliant, moisturizer/humectant, buffering | superstar | |
| Sodium Hyaluronate | skin-identical ingredient, moisturizer/humectant | 0, 0 | goodie |
| Sodium Benzoate | preservative | ||
| Disodium EDTA | chelating | ||
| Tetrapeptide-30 | skin brightening | goodie | |
| Xanthan Gum | viscosity controlling | ||
| Sodium Metabisulfite | antioxidant, preservative | ||
| Calcium Gluconate | moisturizer/humectant |
Medik8 Oxy-r PeptidesIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
- It’s a polyhydroxy acid (PHA), that is often referred to as next generation AHA
- It gently lifts off dead skin cells form the skin surface making skin smooth and even
- In the long term it provides anti-aging benefits, like increased skin thickness and decreased wrinkles (though a tad less than even more proven superstar AHAs)
- It’s a great moisturizer and even helps to repair impaired skin barrier
- It’s antioxidant, and does not make your skin more sensitive to the sun
- It can be used even if your skin is very sensitive, rosacea prone or if you are post cosmetic procedure
A skin-whitening peptide that goes by the trade name GenoWhite. The manufacturer claims that it hinders the mechanism of pigmentation in two ways: first, it inhibits melanin generating enzymes like Tyrosinase so that less pigment is formed and then it also hinders the transport of the pigment to the upper layers of the skin where it becomes visible (little organelles called melanosomes carry the pigment upwards).
The in-vivo (made on real people) test of the manufacturer shows great spot-fading results after 56 days using 2% GenoWhite (with the first visible results showing already after 14 days).
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
- It’s the second most researched AHA after glycolic acid
- It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
- It also has amazing skin hydrating properties
- In higher concentration (10% and up) it improves skin firmness, thickness and wrinkles
- Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
- Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
A four amino acid peptide (Proline – Lysine – Glutamic Acid – Lysine; PKEK) whose main magic power is to fade hyperpigmentation (aka age spots) and even out the skin tone.
According to its German manufacturer, Tetrapeptide-30 has a nice anti-inflammatory function that leads to a dual action in hindering the pigmentation process. It acts as a tyrosinase inhibitor (the famous enzyme needed to create melanin), and it also blocks the transfer of the melanin up into the top layers of the skin.
The manufacturer has done several clinical studies to back up its claims and examined what Tetrapeptide-30 is doing on Caucasian, Asian as well as on ethnic skin. The results confirmed skin-brightening, reduction of age spots, reduction of skin redness and even some reduction of acne lesions. In the reduction of age spots, the peptide showed some synergistic effects with the nice vitamin-C derivative, called SAP.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
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| what‑it‑does | solvent |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | antimicrobial/antibacterial | antioxidant | skin brightening |
| what‑it‑does | skin brightening |
| what‑it‑does | exfoliant | chelating |
| what‑it‑does | skin brightening |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | exfoliant | moisturizer/humectant | buffering |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | preservative |
| what‑it‑does | chelating |
| what‑it‑does | skin brightening |
| what‑it‑does | viscosity controlling |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | moisturizer/humectant |