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Leo Pharma Nanobase

Nanobase

For dry skin with both quick and lasting effect as adding fatty ingredients that would normally take days to produce skin alone.
Uploaded by: dianasto on

Ingredients overview

Warning: This ingredient list seems to miss preservatives necessary for creating safe products. Read here for more detail.

Leo Pharma Nanobase
Ingredients explained

Also-called: Petroleum jelly, Vaseline | What-it-does: emollient

The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.

The unique thing about petrolatum is that it is the most effective occlusive agent known today. While the occlusivity of mineral oil is in the same league as the occlusivity of plant oils, petrolatum is in a league of its own. It sits on top of the skin and hinders so-called transepidermal water loss (TEWL) like nothing else.

Also-called: Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

We don't have description for this ingredient yet.

Also-called: Mineral Oil | What-it-does: emollient, solvent | Irritancy: 0 | Comedogenicity: 0-2

The famous or maybe rather infamous mineral oil. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. It is a very controversial ingredient with pros and cons and plenty of myths around it. So let us see them:  

The pros of mineral oil
Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert.

It is a great emollient and moisturizer working mainly by occlusivity. Occlusivity is one of the basic mechanisms of how moisturizers work and it means that mineral oil sits on top of the skin and hinders so-called trans-epidermal water loss, i.e water evaporating out of your skin. When compared to heavy-duty plant oil, extra virgin coconut oil, the two of them were equally efficient and safe as moisturizers in treating xerosis, a skin condition connected to very dry skin.

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: emulsifying | Irritancy: 0 | Comedogenicity: 3

A mainly oil-loving, vegetable raw material based ingredient that helps water and oil to mix together, aka emulsifier. It can also function as a wetting and dispersing agent helping insoluble particles such as color pigments or inorganic sunscreens (zinc/titanium dioxide) to disperse nice and even in liquids.  

Chemically speaking, it comes from the attachment of sorbitan (a dehydrated sorbitol (sugar) molecule) with the unsaturated fatty acid Oleic Acid, that creates a partly water (the sorbitan part) and partly oil soluble (oleic part) molecule. 

Also-called: Carnauba Wax | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

A vegetable wax coming from the leaves of the Brazilian tropical palm tree, Copernicia cerifera. Similar to other waxes, it is used to stabilize and give body to products, or to keep stick type formulas solid. It is the hardest natural wax with a high melting point (around 85C) and high gloss making it a great wax choice for lip products.

Cholesterol - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 0

It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. Together with ceramides and fatty acids, they play a vital role in having a healthy skin barrier and keeping the skin hydrated. 

Apart from being an important skin-identical ingredient, it's also an emollient and stabilizer

Ceramide 6 - goodie
Also-called: Ceramide 6 II;Ceramide AP | What-it-does: skin-identical ingredient

A type of ceramide that can be found naturally in the upper layer of the skin. Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. 

We have written way more about ceramides at ceramide 1, so click here to know more.

Also-called: Omega-9 fatty acid | What-it-does: emollient, emulsifying

A common fatty acid that can be found in lots of plant oils. Its name, "oleic", means derived from olive oil, a plant oil rich in oleic acid, but avocado, macadamia and marula oils, just to name a few, are also oleic rich.

Its chemical structure is monounsaturated, meaning it has one double bond (cis-9) that makes it less kinky than polyunsaturated fatty acids with multiple double bonds. Less kinkiness means that oleic acid and OA-rich oils are a bit thicker and heavier than their LA-rich siblings.

What-it-does: skin-identical ingredient, emollient, emulsifying | Irritancy: 0 | Comedogenicity: 2

A fatty acid that can be found naturally in the skin. In fact, it's the most common saturated fatty acid found in animals and plants.

As for skincare, it can make the skin feel nice and smooth in moisturizers (emollient) or it can act as a foam building cleansing agent in cleansers. It's also a very popular ingredient in shaving foams. 

What-it-does: buffering

It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.

What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 1

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

You may also want to take a look at...

what‑it‑does emollient
The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.The unique thing about petrolatum is that it is the most effective occlusive agent known today. [more]
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does viscosity controlling | perfuming
what‑it‑does emollient | solvent
irritancy, com. 0, 0-2
A clear, oily liquid that comes from refining crude oil. Even though it is a highly controversial ingredient, the scientific consensus is that it is a safe, non-irritating and effective emollient and moisturizer working mainly by occlusivity. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does emulsifying
irritancy, com. 0, 3
A mainly oil-loving, vegetable raw material based ingredient that helps water and oil to mix together, aka emulsifier. It can also function as a wetting and dispersing agent helping insoluble particles such as color pigments or inorganic sunscreens (zinc/titanium dioxide) to disperse nice and even in liquids.   [more]
what‑it‑does emollient
irritancy, com. 0, 1
A vegetable wax coming from the leaves of the Brazilian tropical palm tree, Copernicia cerifera. Similar to other waxes, it is used to stabilize and give body to products. [more]
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0, 0
It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. [more]
what‑it‑does skin-identical ingredient
A type of ceramide that can be found naturally in the upper layer of the skin. Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated.  We have written way more about ceramides at ceramide 1, so click here to know more. [more]
what‑it‑does emollient | emulsifying
A common fatty acid that can be found in lots of plant oils. Its name, "oleic", means derived from olive oil, a plant oil rich in oleic acid, but avocado, macadamia and marula oils, just to name a few, are also oleic rich. Its chemical structure is monounsaturated, meaning it has one double bond (cis-9) that makes it less kinky than polyunsaturated fatty acids with multi [more]
what‑it‑does skin-identical ingredient | emollient | emulsifying
irritancy, com. 0, 2
A fatty acid that can be found naturally in the skin. It can make the skin feel nice and smooth in moisturizers (emollient) or it can act as a foam building cleansing agent in cleansers. [more]
what‑it‑does buffering
It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.
what‑it‑does viscosity controlling
irritancy, com. 0, 1
A handy white powder that magically converts a liquid into a nice gel formula. [more]