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Cortizone 10 Anti-Itch Creme

Anti-Itch Creme

The non-greasy Creme is designed to go on smoothly and penetrate quickly to relieve itch fast. It also contains healing aloe to soothe itchy, irritated skin.
Uploaded by: wheeleja on 01/09/2019

Cortizone 10 Anti-Itch Creme
Ingredients explained

We don't have description for this ingredient yet.

Also-called: Aloe Vera | What-it-does: soothing, moisturizer/humectant

Aloe Vera is one of today’s magic plants. It does have some very nice properties indeed, though famous dermatologist Leslie Baumann warns us in her book that most of the evidence is anecdotal and the plant might be a bit overhyped.

What research does confirm about Aloe is that it’s a great moisturizer and has several anti-inflammatory (among others contains salicylates, polysaccharides, magnesium lactate and C-glucosyl chromone) as well as some antibacterial components. It also helps wound healing and skin regeneration in general. All in all definitely a goodie. 

What-it-does: astringent, deodorant

We don't have description for this ingredient yet.

Also-called: Cera Alba | What-it-does: emollient, viscosity controlling | Irritancy: 0 | Comedogenicity: 0-2

It's the yellow, solid stuff that you probably know from beeswax candles. It's a natural material produced by honey bees to build their honeycomb.

As for skincare, it's used as an emollient and thickening agent. It's super common in lip balms and lipsticks. 

What-it-does: viscosity controlling

We don't have description for this ingredient yet.

What-it-does: emollient, viscosity controlling | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

A little helper ingredient that can be a thickener, a humectant, a foam booster, an adhesion promoter and a filler. It's a blend of polysaccharides that helps to moisturize and soften the skin. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: absorbent/mattifier

It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding). 

What-it-does: preservative | Irritancy: 0 | Comedogenicity: 0

The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon

Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing that when exposed to sunlight, MP treated skin cells suffered more harm than non-MP treated skin cells. The study was not done with real people on real skin but still - using a good sunscreen next to MP containing products is a good idea. (Well, in fact using a sunscreen is always a good idea. :))

Also-called: Paraffinum Liquidum | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0-2

The famous or maybe rather infamous mineral oil. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. It is a very controversial ingredient with pros and cons and plenty of myths around it. So let us see them:  

The pros of mineral oil
Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert.

It is a great emollient and moisturizer working mainly by occlusivity. Occlusivity is one of the basic mechanisms of how moisturizers work and it means that mineral oil sits on top of the skin and hinders so-called trans-epidermal water loss, i.e water evaporating out of your skin. When compared to heavy-duty plant oil, extra virgin coconut oil, the two of them were equally efficient and safe as moisturizers in treating xerosis, a skin condition connected to very dry skin.

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The other thing that mineral oil is really good at is being non-irritating to the skin. The chemical composition of plant oils is more complex with many more possible allergens or irritating components, while mineral oil is simple, pure and sensitivity to it is extremely rare. If you check out the classic French pharmacy brands and their moisturizers for the most sensitive, allergy prone skin, they usually contain mineral oil. This is no coincidence. 

The cons of mineral oil
The pros of mineral oil can be interpreted as cons if we look at them from another perspective. Not penetrating the skin but mostly just sitting on top of it and not containing biologically active components, like nice fatty acids and vitamins mean that mineral oil does not "nourish" the skin in the way plant oils do. Mineral oil does not give the skin any extra goodness, it is simply a non-irritating moisturizer working mainly by occlusivity. 

The myths around mineral oil
Badmouthing mineral oil is a favorite sport of many, it is a cheap material and being connected to petrolatum makes it fairly easy to demonize. 

While it is true that industrial grade mineral oil contains carcinogenic components (so-called polycyclic compounds), these are completely removed from cosmetic and food grade mineral oil and there is no scientific data showing that the pure, cosmetic grade version is carcinogenic.

What is more, in terms of the general health effects of mineral oils used in cosmetics, a 2017 study reviewed the data on their skin penetration and concluded that "the cosmetic use of mineral oils and waxes does not present a risk to consumers due to a lack of systemic exposure."  

Another super common myth surrounding mineral oil is that it is comedogenic. A 2005 study titled "Is mineral oil comedogenic?" examined this very question and guess what happened? The study concluded that  "based on the animal and human data reported, along with the AAD recommendation, it would appear reasonable to conclude that mineral oil is noncomedogenic in humans.

Overall, we feel that the scaremongering around mineral oil is not justified. For dry and super-sensitive skin types it is a great option. However, if you do not like its origin or its heavy feeling or anything else about it, avoiding it has never been easier. Mineral oil has such a bad reputation nowadays that cosmetic companies hardly dare to use it anymore. 

Also-called: Petroleum jelly, Vaseline | What-it-does: emollient

The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.

The unique thing about petrolatum is that it is the most effective occlusive agent known today. While the occlusivity of mineral oil is in the same league as the occlusivity of plant oils, petrolatum is in a league of its own. It sits on top of the skin and hinders so-called transepidermal water loss (TEWL) like nothing else.

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This comes in handy healing cracked lips or severely dry skin patches, though overdoing it (i.e. reducing TEWL by more than 40%) is not good as it can create a nice moist place for fungi and bacteria to grow.  

As for petrolatum and safety, we can write here pretty much the exact same thing as we have written at mineral oil. There is no evidence whatsoever that cosmetic, USP grade petrolatum is carcinogenic. It also does not absorb into the skin but sits on top of it and that in itself greatly minimises health risks. It also has a long history of safe use, as it was first used as a skincare product more than 100 years ago, in 1872 to be precise. 

It is also non-comedogenic, though its pure form is very heavy and greasy so combination and oily skin types might want to avoid it anyway. 

Overall, it is the gold-standard occlusive agent known today and a tub of Vaseline comes in handy in any household to heal cracked lips or other severely dry skin patches.

What-it-does: preservative | Irritancy: 0 | Comedogenicity: 0

A very common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon.

What-it-does: surfactant/cleansing

We don't have description for this ingredient yet.

Also-called: SLS | What-it-does: surfactant/cleansing | Comedogenicity: 0

The famous or rather infamous SLS (not to be confused with SLES). It is a cleansing agent known for being too good at the job and potentially irritating the skin. But, on the positive side,  it can produce copious, creamy and luxurious foam compared to the more gentle and thus nowadays much more commonly used Sodium Laureth Sulfate.

In fact, SLS is so good at irritating the skin that it is very commonly used in dermatological studies just for that. It is a so-called "primary irritant", a substance that irritates the skin in one go (without prior sensitization) but doesn't do any other big harm (such as being carcinogenic or systematically toxic - those claims are not true). Also, the formula can greatly influence the irritating potential of SLS, and mixing it with other cleaning agents makes it milder

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If it's not in a cleanser, it works as an emulsifier or even as a penetration enhancer for active materials. 

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

You may also want to take a look at...

what‑it‑does soothing | moisturizer/humectant
The famous aloe vera. A great moisturizer and anti-inflammatory ingredient that also helps wound healing and skin regeneration. [more]
what‑it‑does emollient | viscosity controlling
irritancy, com. 0, 0-2
The yellow solid stuff produced by honey bees to build their honeycomb. As for skincare, it's used as an emollient and thickening agent. [more]
what‑it‑does viscosity controlling
what‑it‑does emollient | viscosity controlling
irritancy, com. 1, 2
A super common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams. [more]
what‑it‑does viscosity controlling | moisturizer/humectant
A little helper ingredient that can be a thickener, a humectant, a foam booster, an adhesion promoter and a filler. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding). 
what‑it‑does preservative
irritancy, com. 0, 0
The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon.  Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) sho [more]
what‑it‑does emollient
irritancy, com. 0, 0-2
A clear, oily liquid that comes from refining crude oil. Even though it is a highly controversial ingredient, the scientific consensus is that it is a safe, non-irritating and effective emollient and moisturizer working mainly by occlusivity. [more]
what‑it‑does emollient
The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.The unique thing about petrolatum is that it is the most effective occlusive agent known today. [more]
what‑it‑does preservative
irritancy, com. 0, 0
A very common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. [more]
what‑it‑does surfactant/cleansing
what‑it‑does surfactant/cleansing
com. 0
The famous or rather infamous SLS (not to be confused with SLES). It is a cleansing agent known for being too good at the job and potentially irritating the skin. [more]
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]