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Dimethylmethoxy Chromanol

Also-called-like-this: Lipochroman-6, LC-6
What-it-does: antioxidant

Official CosIng Information


A synthetic molecule that has a similar structure to α-Tocopherol (vitamin E) and works as a super potent antioxidant. It's known for not only protecting against reactive oxygen species (ROS) but also against reactive nitrogen species (RNS) (both are evil reactive molecules that cause damage to cells and tissues and are responsible for several mechanisms which trigger skin aging). 

There are different methods to evaluate the antioxidant power of an ingredient and according to the so-called TBA-assay, Dimethylmethoxy Chromanol is a more potent antioxidant than BHT, trolox or tocopherol. Its recommended dosage is only 0.01-0.05%, that also signals how potent Lipochroman-6 is. 

Show me some proof

  • Nonell, S., et al. "Singlet molecular oxygen quenching by the antioxidant dimethylmethoxy chromanol in solution and in ex vivo porcine skin." International journal of cosmetic science 35.3 (2013): 272-280.
  • Buenger, J., et al. "An interlaboratory comparison of methods used to assess antioxidant potentials." International journal of cosmetic science 28.2 (2006): 135-146.

Products with Dimethylmethoxy Chromanol

Ecooking A Vitamin Capsules Verso Anti Pollution For Daily Use Ecooking Vitamin E Serum SkinScript Rx Smoked Bourbon Enzyme NIOD Survival 0 Niks Golden Lipid Complex Dr. Loretta Intense Replenishing Serum Neutrogena Skin Detox Dual Action Moisturizer Sympli Beautiful Rejuvenating Night Cream Gerovital Retinol NIOD Survival 10 NassifMD Dermaceuticals Hydro-Screen Hydrating Serum Peter Thomas Roth Vital-E™ Microbiome Age Defense Cream Solal C-Serum Biologique Recherche Serum Pigm 400 NIOD Survival 20 NIOD Survival SPF 30 Peter Thomas Roth Vital-E™ Microbiome Age Defense Eye Cream Westman Atelier Super Loaded Tinted Highlight Biologique Recherche Creme Pigm 400 Colorescience Sunforgettable® Total Protection™ Body Shield Spf 50 Alpha-H Hyaluronic 8 Christian Breton Paris Eye Priority | Uv Eye Protection Spf30 NeoCutis Réactive Antioxidant Serum BABOR Pollution Protect Medik8 Breakout Defence + Age Repair™ Regimen Lab Level Serum Regimen Lab Vitamin X Colorescience Sunforgettable Total Protection Body Shield Bronze Spf 50 Diadermine Lift+ Super Filler Hyaluron Anti-Age Nachtcreme Your Best Face (YBF-Skincare) Boost Daily Clarifying Moisturizer Stubborn Cosmetics Skin Mercy Antioxidant Face Mist Zelens Intense Defence Antioxidant Serum Biologique Recherche Creme Masque Vernix Biologique Recherche Masque Vernix Philosophy Renewed Hope In A Jar Renewing Dew Concentrate WBEAUTY Treat Anti-Ageing Eye Cream OSSOLA Skincare Super Serum Regimen Lab C.R.E.A.M. Max Factor 3 in 1 Miracle Prep Beauty Protect Primer SPF 30 PA+++ SENTÉ Intensive Bio Complete Cream YourGoodSkin Provitamin Overnight Cream Dior One Essential Skin Boosting Super Serum Pika Pika Sparkling Bright Fruity Cleansing Liquid YourGoodSkin Instant Dryness Rescue Moisturiser Chantecaille Anti Pollution Mattifying Cream LACURA Q10 Multi-Intensive Serum LACURA Q10 Renew Day Cream WBEAUTY Protect Complete Shield Spf50 Colorescience Unforgettable Total Protection Berry Color Balm Spf 50