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Dimethylmethoxy Chromanol

Also-called-like-this: Lipochroman-6, LC-6
What-it-does: antioxidant


A synthetic molecule that has a similar structure to α-Tocopherol (vitamin E) and works as a super potent antioxidant. It's known for not only protecting against reactive oxygen species (ROS) but also against reactive nitrogen species (RNS) (both are evil reactive molecules that cause damage to cells and tissues and are responsible for several mechanisms which trigger skin aging). 

There are different methods to evaluate the antioxidant power of an ingredient and according to the so-called TBA-assay, Dimethylmethoxy Chromanol is a more potent antioxidant than BHT, trolox or tocopherol. Its recommended dosage is only 0.01-0.05%, that also signals how potent Lipochroman-6 is. 

Show me some proof

  • Nonell, S., et al. "Singlet molecular oxygen quenching by the antioxidant dimethylmethoxy chromanol in solution and in ex vivo porcine skin." International journal of cosmetic science 35.3 (2013): 272-280.
  • Buenger, J., et al. "An interlaboratory comparison of methods used to assess antioxidant potentials." International journal of cosmetic science 28.2 (2006): 135-146.

Products with Dimethylmethoxy Chromanol

WBEAUTY Hydrating Face Mist AestheticsRX Vitamin A Serum Grown Alchemist Detox Serum Antioxidant+3 Complex Lovinah Red-C Ampoule The derma CO 0.3% Retinol Serum Ecooking A Vitamin Capsules RoC Retinol Correxion Line Smoothing Night Serum Capsules Verso Anti Pollution For Daily Use AestheticsRX Anti-ageing-regeneration-formula Ecooking Vitamin E Serum SkinScript Rx Smoked Bourbon Enzyme The derma CO 0.1% Retinol Serum Farmec Romania Gerovital H3 Retinol Wrinkles Prevention Cream NIOD Survival 0 The Chemist Look Booster Retin-E Bagóvit CC Cream Circadia Revita-Cyte Complex Dior One Essential Eye Serum Niks Golden Lipid Complex Platinum Skin Care Luminosity Platinum Skin Care Retinal .20% Derma Essentia 25% Zinc Oxide Sunscreen Dry Touch Dr. Loretta Intense Replenishing Serum ERTO’S Retinol Serum Neutrogena Skin Detox Dual Action Moisturizer Sympli Beautiful Rejuvenating Night Cream Blisskin 3D Mattifying Sunscreen Spf 50 Pa+++ Gerovital Retinol NIOD Survival 10 NIOD Survival 10 Rebloom Broad Spectrum Sunscreen SPF 50 PA+++ IR Blue Light Renewcell Eclipse Solaire Venya Healthy Aging Multifunctional Serum Breylee Pomegranate Serum Dr. Loretta Eye Tightening Gel Dr. brandt Skincare Magnetight Age-Defier™ Mask Gerovital H3 Retinol Anti-Wrinkle Eye Contour Cream I Trust Nature Honey Sun Protection SPF 50+ PA+++ NassifMD Dermaceuticals Hydro-Screen Hydrating Serum Peter Thomas Roth Vital-E™ Microbiome Age Defense Cream Renewcell Cosmedica Eclipse Solaire Solal C-Serum Biologique Recherche Serum Pigm 400 NIOD Survival 20 NIOD Survival SPF 30 Nuface Super Antioxidant Booster Serum Peter Thomas Roth Vital-E™ Microbiome Age Defense Eye Cream Westman Atelier Super Loaded Tinted Highlight Beverly Hills MD Supercharged Antioxidant Serum™ Biologique Recherche Creme Pigm 400