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Dimethylmethoxy Chromanol

Also-called-like-this: Lipochroman-6, LC-6
What-it-does: antioxidant

Official CosIng Information


A synthetic molecule that has a similar structure to α-Tocopherol (vitamin E) and works as a super potent antioxidant. It's known for not only protecting against reactive oxygen species (ROS) but also against reactive nitrogen species (RNS) (both are evil reactive molecules that cause damage to cells and tissues and are responsible for several mechanisms which trigger skin aging). 

There are different methods to evaluate the antioxidant power of an ingredient and according to the so-called TBA-assay, Dimethylmethoxy Chromanol is a more potent antioxidant than BHT, trolox or tocopherol. Its recommended dosage is only 0.01-0.05%, that also signals how potent Lipochroman-6 is. 

Show me some proof

  • Nonell, S., et al. "Singlet molecular oxygen quenching by the antioxidant dimethylmethoxy chromanol in solution and in ex vivo porcine skin." International journal of cosmetic science 35.3 (2013): 272-280.
  • Buenger, J., et al. "An interlaboratory comparison of methods used to assess antioxidant potentials." International journal of cosmetic science 28.2 (2006): 135-146.

Products with Dimethylmethoxy Chromanol

Ecooking A Vitamin Capsules Verso Anti Pollution For Daily Use Ecooking Vitamin E Serum SkinScript Rx Smoked Bourbon Enzyme NIOD Survival 0 Bagóvit CC Cream Niks Golden Lipid Complex Dr. Loretta Intense Replenishing Serum Neutrogena Skin Detox Dual Action Moisturizer Sympli Beautiful Rejuvenating Night Cream Gerovital Retinol NIOD Survival 10 Dr. Loretta Eye Tightening Gel NassifMD Dermaceuticals Hydro-Screen Hydrating Serum Peter Thomas Roth Vital-E™ Microbiome Age Defense Cream Solal C-Serum Biologique Recherche Serum Pigm 400 NIOD Survival 20 NIOD Survival SPF 30 Peter Thomas Roth Vital-E™ Microbiome Age Defense Eye Cream Westman Atelier Super Loaded Tinted Highlight Biologique Recherche Creme Pigm 400 Colorescience Sunforgettable® Total Protection™ Body Shield Spf 50 Alpha-H Hyaluronic 8 Christian Breton Paris Eye Priority | Uv Eye Protection Spf30 Elizabeth Arden Eight Hour Great 8 Daily Defense Moisturizer Regimen Level Serum Balea MEN 5in1 Anti-Müdigkeits Booster Energy NeoCutis Réactive Antioxidant Serum Pika Pika Soymilk Bouncy Lotion BABOR Pollution Protect Diadermine Lift+ Sun Protect Spf 30 L'BEL Essential Moisturizing Eye And Face Makeup Remover Lotion All Skin Types Medik8 Breakout Defence + Age Repair™ Regimen Lab Level Serum Regimen Lab Vitamin X Colorescience Sunforgettable Total Protection Body Shield Bronze Spf 50 Diadermine Lift+ Super Filler Hyaluron Anti-Age Nachtcreme Your Best Face (YBF-Skincare) Boost Daily Clarifying Moisturizer Stubborn Cosmetics Skin Mercy Antioxidant Face Mist Zelens Intense Defence Antioxidant Serum Biologique Recherche Creme Masque Vernix Biologique Recherche Masque Vernix Mesoestetic Stem Cell Active Growth Factor Philosophy Renewed Hope In A Jar Renewing Dew Concentrate Pika Pika Soymilk Bouncy All-In-One Gel Trinny London BFF De-Stress Tinted Serum WBEAUTY Treat Anti-Ageing Eye Cream OSSOLA Skincare Super Serum Regimen Lab C.R.E.A.M.