A synthetic molecule that has a similar structure to α-Tocopherol (vitamin E) and works as a super potent antioxidant. It's known for not only protecting against reactive oxygen species (ROS) but also against reactive nitrogen species (RNS) (both are evil reactive molecules that cause damage to cells and tissues and are responsible for several mechanisms which trigger skin aging).
There are different methods to evaluate the antioxidant power of an ingredient and according to the so-called TBA-assay, Dimethylmethoxy Chromanol is a more potent antioxidant than BHT, trolox or tocopherol. Its recommended dosage is only 0.01-0.05%, that also signals how potent Lipochroman-6 is.
- Nonell, S., et al. "Singlet molecular oxygen quenching by the antioxidant dimethylmethoxy chromanol in solution and in ex vivo porcine skin." International journal of cosmetic science 35.3 (2013): 272-280.
- Buenger, J., et al. "An interlaboratory comparison of methods used to assess antioxidant potentials." International journal of cosmetic science 28.2 (2006): 135-146.