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Dimethylmethoxy Chromanol

Also-called-like-this: Lipochroman-6, LC-6
What-it-does: antioxidant


A synthetic molecule that has a similar structure to α-Tocopherol (vitamin E) and works as a super potent antioxidant. It's known for not only protecting against reactive oxygen species (ROS) but also against reactive nitrogen species (RNS) (both are evil reactive molecules that cause damage to cells and tissues and are responsible for several mechanisms which trigger skin aging). 

There are different methods to evaluate the antioxidant power of an ingredient and according to the so-called TBA-assay, Dimethylmethoxy Chromanol is a more potent antioxidant than BHT, trolox or tocopherol. Its recommended dosage is only 0.01-0.05%, that also signals how potent Lipochroman-6 is. 

Show me some proof

  • Nonell, S., et al. "Singlet molecular oxygen quenching by the antioxidant dimethylmethoxy chromanol in solution and in ex vivo porcine skin." International journal of cosmetic science 35.3 (2013): 272-280.
  • Buenger, J., et al. "An interlaboratory comparison of methods used to assess antioxidant potentials." International journal of cosmetic science 28.2 (2006): 135-146.

Products with Dimethylmethoxy Chromanol

WBEAUTY Hydrating Face Mist AestheticsRX Vitamin A Serum Grown Alchemist Detox Serum Antioxidant+3 Complex Lovinah Red-C Ampoule O Cosmedics Gentle Antioxidant Cleanser Re'equil 20% Vitamin C Serum For Wrinkles And Dullness The derma CO 0.3% Retinol Serum Ecooking A Vitamin Capsules Proya Elastic Brightening Youth Essence RoC Retinol Correxion Line Smoothing Night Serum Capsules Verso Anti Pollution For Daily Use AestheticsRX Anti-ageing-regeneration-formula Ecooking Vitamin E Serum SkinScript Rx Smoked Bourbon Enzyme The derma CO 0.1% Retinol Serum Farmec Romania Gerovital H3 Retinol Wrinkles Prevention Cream FlawlessCanvas Free Radicals Scavenger NIOD Survival 0 The Chemist Look Booster Retin-E Bagóvit CC Cream Circadia Revita-Cyte Complex Dior One Essential Eye Serum Lancaster Golden Tan Maximizer After Sun Oil Melanie Jane Skincare Vita Soothe Niks Golden Lipid Complex Platinum Skin Care Luminosity Platinum Skin Care Retinal .20% Young Goose Bio-barrier Derma Essentia 25% Zinc Oxide Sunscreen Dry Touch Dr. Loretta Intense Replenishing Serum ERTO’S Retinol Serum Lanmeri Pure Radiance 15% C E + Ferulic Neutrogena Skin Detox Dual Action Moisturizer Standard Beauty Skin Juice - Glow Guardian Mist Sympli Beautiful Rejuvenating Night Cream Anne moller Aqua Non Stop SPF50+ Blisskin 3D Mattifying Sunscreen Spf 50 Pa+++ Dermosys Broad Spectrum Sunscreen SPF 50+ Garancia L'elixir Du Marabout Gerovital Retinol NIOD Survival 10 NIOD Survival 10 O Cosmedics Gentle Antioxidant Cleanser Rebloom Broad Spectrum Sunscreen SPF 50 PA+++ IR Blue Light Renewcell Eclipse Solaire Sunscreen Venya Healthy Aging Multifunctional Serum Anne moller NON STOP sunstick SPF50+ Breylee Pomegranate Serum Clinians Detox Tech Dr. Brandt Skincare Magnetight Age-Defier™ Mask