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| Ingredient name | what-it-does | irr., com. | ID-Rating |
|---|---|---|---|
| Sulfur Praecipitatum (10%) | anti-acne, antimicrobial/​antibacterial | 0, 0-3 | goodie |
| Petrolatum | emollient |
Dr. Sana Sulfur Ointment 10%Ingredients explained
A yellowish element that smells of rotten eggs and it might be familiar to you from the periodic table (has the symbol S in there). It has a long history of medicinal use thanks to its antifungal, antibacterial and keratolytic activity. It used to be a very common ingredient in the treatment of inflammation-related skin diseases such as acne, rosacea and seborrheic dermatitis, however, due to its malodorousness, it is less popular nowadays.
Sulfur's precise mechanism of action is not known, but we do know that its effectiveness depends on its direct interaction with the skin surface, meaning the smaller the particle size, the better the effect. The United States Pharmacopeia lists two types of sulfur, sublimed and precipitated. The latter one has a smaller particle size and counts as a superior version.
Sulfur is also a team-player and works well when combined with other anti-acne agents, such as salicylic acid or sodium sulfacetamide. In fact, the combination of 10% sodium sulfacetamide and 5% sulfur is the active ingredient duo of several Rx-only anti-acne products.
As for the disadvantages, there is the rotten egg smell. Also in higher concentrations, it might cause a mild burning sensation and dry skin. If you are new to sulfur, patch testing it first is a good idea.
The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.
The unique thing about petrolatum is that it is the most effective occlusive agent known today. While the occlusivity of mineral oil is in the same league as the occlusivity of plant oils, petrolatum is in a league of its own. It sits on top of the skin and hinders so-called transepidermal water loss (TEWL) like nothing else.
This comes in handy healing cracked lips or severely dry skin patches, though overdoing it (i.e. reducing TEWL by more than 40%) is not good as it can create a nice moist place for fungi and bacteria to grow.
As for petrolatum and safety, we can write here pretty much the exact same thing as we have written at mineral oil. There is no evidence whatsoever that cosmetic, USP grade petrolatum is carcinogenic. It also does not absorb into the skin but sits on top of it and that in itself greatly minimises health risks. It also has a long history of safe use, as it was first used as a skincare product more than 100 years ago, in 1872 to be precise.
It is also non-comedogenic, though its pure form is very heavy and greasy so combination and oily skin types might want to avoid it anyway.
Overall, it is the gold-standard occlusive agent known today and a tub of Vaseline comes in handy in any household to heal cracked lips or other severely dry skin patches.
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| what‑it‑does | anti-acne | antimicrobial/antibacterial |
| irritancy, com. | 0, 0-3 |
| what‑it‑does | emollient |