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Thioctic Acid

Also-called-like-this: Alpha-Lipoic Acid
What-it-does: antioxidant


Alpha-Lipoic Acid (ALA) is a great antioxidant that's also part of the body's natural antioxidant system. It's soluble both in water-rich and lipid-rich environments so it's versatile and can interact with many types of evil oxidants as well as other nice antioxidants. 

ALA seems to be a great choice for topical use as studies show it can penetrate the skin rapidly where it's converted to DHLA (dihydrolipoic acid), an even more potent antioxidant molecule.  A nicely designed (we mean double-blind, placebo-controlled) 12-week study from 2003 confirmed that 5% ALA cream can decrease skin roughness and improve general signs of photoaging statistically significantly.  A slight catch, though, is that burning and warmth in the skin was quite a common side effect, especially in the first 4 weeks. 

All in all, ALA is definitely a research-proven, great antioxidant but if your skin is sensitive higher concentrations might not be for you.

Show me some proof

  • Beitner, Harry. "Randomized, placebo‐controlled, double blind study on the clinical efficacy of a cream containing 5% α‐lipoic acid related to photoageing of facial skin." British Journal of Dermatology 149.4 (2003): 841-849.
  • Podda, Maurizio, et al. "Activity of alpha-lipoic acid in the protection against oxidative stress in skin." Oxidants and antioxidants in cutaneous biology. Vol. 29. Karger Publishers, 2001. 43-51.

Products with Thioctic Acid

Ruruberry Alpha Lipoic Acid The Ordinary Alpha Lipoic Acid 5% Perricone MD High Potency Classics Face Firming Serum about-face essentials Resqoil laborest Tiobec Crema DrGL Skin Repair La Clinica 30% Vitamin C Anhydrous Humectant Serum Make Happy Skin Super Antioxidant Serum verabella MoistureScreen Herbal Glo See Younger Looking Skin Facial Masque Jabushe Original Cream Kalahari Alpha Lipoic Complex With Astaxanthin LuvrePro Gel Concentrado Antiage Descongestivo Skoah. Lip Dip Trader Joe's Nourish Antioxidant Facial Serum face doctor Facesurgeon ATACHE Biological Triple Antioxidant Night Protector ClearChoice Hydrating Cleanser Derma E Firming Dmae Moisturizer Derma E Firming Dmae Toner FARMEC Gerovital Equilibrium Multivitamin Vials Missha Firming Gel Eye Patch Theraderm OPC Reparative Serum Cosmedix Radiance Age Restorative Serum Derma E Ester C Cleanser EXEL Gel Cream Renovador Glimmer goddess Organic Resveratrol Life Choice Dmae Restorative Cream Medik8 Pore Minimising Tonic Perricone MD High Potency Classics Nutritive Cleanser Perricone MD Skin Perfecting Serum Reviva Labs Alpha Lipoic Acid Vitamin C Ester Dmae Créme artnaturals Vitamin C Toner Ausceuticals Retinol Serum (Reformulated And Now In Airless Packaging) Herbal Glo See Younger Skin Daytime Moisturizer Jabushe Intensive Age Defense Soft Perricone MD Advanced Eye Area Therapy Satara Dead Sea Firming Night Cream Zelens Intense Defence Antioxidant Serum Aurelia Emulsión Humectante Ausceuticals Retinol Serum Beauty Clinic Beverly Hills Crema Botox Effect Antirughe Derma E Firming DMAE Moisturizer Derma E Firming DMAE Serum Derma E Firming Dmae Moisturizer Alpha Lipoic Acid & C-Ester Paula's Choice Resist Super Antioxidant Serum Phace bioactive Detoxifying Gel Cleanser Shine Skincare Co Youth Serum - Peptide Serum Skoah. Lip Dip 30 Source Naturals Skin Eternal Serum