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Thioctic Acid

goodie
Also-called-like-this: Alpha-Lipoic Acid
What-it-does: antioxidant

Official CosIng Information

Details

Alpha-Lipoic Acid (ALA) is a great antioxidant that's also part of the body's natural antioxidant system. It's soluble both in water-rich and lipid-rich environments so it's versatile and can interact with many types of evil oxidants as well as other nice antioxidants. 

ALA seems to be a great choice for topical use as studies show it can penetrate the skin rapidly where it's converted to DHLA (dihydrolipoic acid), an even more potent antioxidant molecule.  A nicely designed (we mean double-blind, placebo-controlled) 12-week study from 2003 confirmed that 5% ALA cream can decrease skin roughness and improve general signs of photoaging statistically significantly.  A slight catch, though, is that burning and warmth in the skin was quite a common side effect, especially in the first 4 weeks. 

All in all, ALA is definitely a research-proven, great antioxidant but if your skin is sensitive higher concentrations might not be for you.

Show me some proof

  • Beitner, Harry. "Randomized, placebo‐controlled, double blind study on the clinical efficacy of a cream containing 5% α‐lipoic acid related to photoageing of facial skin." British Journal of Dermatology 149.4 (2003): 841-849.
  • Podda, Maurizio, et al. "Activity of alpha-lipoic acid in the protection against oxidative stress in skin." Oxidants and antioxidants in cutaneous biology. Vol. 29. Karger Publishers, 2001. 43-51.

Products with Thioctic Acid

The Ordinary Alpha Lipoic Acid 5% Perricone MD High Potency Classics Face Firming Serum about-face essentials Resqoil DrGL Skin Repair Make Happy Skin Super Antioxidant Serum verabella MoistureScreen Trader Joe's Nourish Antioxidant Facial Serum Derma E Firming Dmae Moisturizer Derma E Firming Dmae Toner Missha Firming Gel Eye Patch Cosmedix Radiance Age Restorative Serum Derma E Ester C Cleanser Medik8 Pore Minimising Tonic Perricone MD High Potency Classics Nutritive Cleanser Perricone MD Skin Perfecting Serum Reviva Labs Alpha Lipoic Acid Vitamin C Ester Dmae Créme Ausceuticals Retinol Serum (Reformulated And Now In Airless Packaging) Perricone MD Advanced Eye Area Therapy Zelens Intense Defence Antioxidant Serum Ausceuticals Retinol Serum Derma E Firming DMAE Moisturizer Derma E Firming DMAE Serum Derma E Firming Dmae Moisturizer Alpha Lipoic Acid & C-Ester Paula's Choice Resist Super Antioxidant Serum Phace bioactive Detoxifying Gel Cleanser Shine Skincare Co Youth Serum - Peptide Serum Source Naturals Skin Eternal, Sensitive Skin Cream The Organic Pharmacy Antioxidant Face Serum 100% Pure Vitamin C Serum ATACHE C Vital AHA Gel Cosmedix Phytoharmony Balancing Moisturizer Nuface 24K Gel Primer Nuface Firm 24K Gold Gel Primer Perricone MD Instant Blur BRAD Biophotonic Skin Care Essential Elixir Pore-Tightening Resurfacing Replenish Serum Cosmedix Phytoclear Clarifying Moisturizer Glory Fountain Of Youth Jeffrey James Botanicals The Toner Made from earth Vitamin Enhanced Face Firming Serum Perricone MD High Potency Classics Firming Evening Repair Bioelements Multi-Task Eye Creme Perricone MD Thio:Plex Intensive 2-Step Brightening System [Step 1: Intensive Base] Pevonia Timeless Repair Cream Ausceuticals 20% Vitamin C Serum (Reformulated) Eyetitude Retinol Eye Cream LifeCell All-In-One Skin-Tightening Treatment Perricone MD Cold Plasma Plus+ Neck & Chest Broad Spectrum SPF 25 Perricone MD Multi-Action Overnight Intensive Firming Mask Skin Actives Every Lipid Serum Skin Actives Every Lipid Serum - Vegan