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Thioctic Acid

goodie
Also-called-like-this: Alpha-Lipoic Acid
What-it-does: antioxidant

Official CosIng Information

Details

Alpha-Lipoic Acid (ALA) is a great antioxidant that's also part of the body's natural antioxidant system. It's soluble both in water-rich and lipid-rich environments so it's versatile and can interact with many types of evil oxidants as well as other nice antioxidants. 

ALA seems to be a great choice for topical use as studies show it can penetrate the skin rapidly where it's converted to DHLA (dihydrolipoic acid), an even more potent antioxidant molecule.  A nicely designed (we mean double-blind, placebo-controlled) 12-week study from 2003 confirmed that 5% ALA cream can decrease skin roughness and improve general signs of photoaging statistically significantly.  A slight catch, though, is that burning and warmth in the skin was quite a common side effect, especially in the first 4 weeks. 

All in all, ALA is definitely a research-proven, great antioxidant but if your skin is sensitive higher concentrations might not be for you.

Show me some proof

  • Beitner, Harry. "Randomized, placebo‐controlled, double blind study on the clinical efficacy of a cream containing 5% α‐lipoic acid related to photoageing of facial skin." British Journal of Dermatology 149.4 (2003): 841-849.
  • Podda, Maurizio, et al. "Activity of alpha-lipoic acid in the protection against oxidative stress in skin." Oxidants and antioxidants in cutaneous biology. Vol. 29. Karger Publishers, 2001. 43-51.

Products with Thioctic Acid

The Ordinary Alpha Lipoic Acid 5% Perricone MD High Potency Classics Face Firming Serum about-face essentials Resqoil DrGL Skin Repair Derma E Firming Dmae Toner Cosmedix Radiance Age Restorative Serum Derma E Ester C Cleanser Medik8 Pore Minimising Tonic Perricone MD High Potency Classics Nutritive Cleanser Perricone MD Skin Perfecting Serum Ausceuticals Retinol Serum (Reformulated And Now In Airless Packaging) Perricone MD Advanced Eye Area Therapy Zelens Intense Defence Antioxidant Serum Ausceuticals Retinol Serum Derma E Firming DMAE Serum Paula's Choice Resist Super Antioxidant Serum Phace bioactive Detoxifying Gel Cleanser Shine Skincare Co Youth Serum - Peptide Serum ATACHE C Vital AHA Gel Cosmedix Phytoharmony Balancing Moisturizer Nuface 24K Gel Primer Nuface Firm 24K Gold Gel Primer Perricone MD Instant Blur BRAD Biophotonic Skin Care Essential Elixir Pore-Tightening Resurfacing Replenish Serum Cosmedix Phytoclear Clarifying Moisturizer Jeffrey James Botanicals The Toner Made from earth Vitamin Enhanced Face Firming Serum Perricone MD High Potency Classics Firming Evening Repair Bioelements Multi-Task Eye Creme Perricone MD Cold Plasma Sub-D/Neck Perricone MD Thio:Plex Intensive 2-Step Brightening System [Step 1: Intensive Base] Eyetitude Retinol Eye Cream Perricone MD Cold Plasma Plus+ Neck & Chest Broad Spectrum SPF 25 Perricone MD Multi-Action Overnight Intensive Firming Mask Skin Actives Every Lipid Serum Skin Actives Every Lipid Serum - Vegan South Beach Skincare Lifecell Trader Joe's Nourish All In One Facial Cleanser Ausceuticals 20% Vitamin C Serum (Reformulated) EltaMD Pm Therapy Facial Moisturizer Osmosis Renew Level 4 Vitamin A Serum Osmosis Replenish- Antioxidant Infusion Serum Osmosis Skincare MD Replenish Antioxidant Infusion Serum Osmosis Skinsare Correct Level 3 Vitamin A Serum Perricone MD Cocoa Moisture Mask Skin Actives Vitamin C Serum StriVectin Oleic Rapid Recovery Milk Mira-skin Hyaluronic Serum Neogen Agecure Antiager Facial Base Coat 100% Pure Fruit Pigmented® Full Coverage Water Foundation