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Oligopeptide-68

goodie
Also-called-like-this: ß-White
What-it-does: skin brightening

Details

A skin-brightening peptide that is claimed to have a unique mechanism of action on lightening both constitutive (our default skin color) and facultative (such as tanning) pigmentation. It works by inhibiting the MITF gene that plays an important role in controlling melanin producing skin cells called melanocytes.

In the in-vivo (made on real people) test of the manufacturer, 23 Asian volunteers used a 5% ß-White formula for 56 days twice a day and 87% reported a more uniform skin tone and 91% felt that their skin was brighter than before.

As for research, we found one study from 2016 that combined Oligopeptide-68 with sunscreen and another skin-lightening active called Diacetyl Boldine (DAB). The conclusion was that "combination of DAB serum at night and DAB/TGF-β1 biomimetic oligopeptide-68/sunscreen cream in the morning and at noon was effective and safe for facial melasma. They were superior to HQ in pigment reduction."  HQ refers to the famous Hydroquinone that's the gold-standard skin-lightening ingredient, so having comparable or superior results is a very promising outcome. 

Overall, if you are into skin-lightening or fading pigmentation spots, Oligopeptide-68 might be something to try.

Show me some proof

  • Pratchyapurit, Walai‐orn. "Combined use of two formulations containing diacetyl boldine, TGF‐β1 biomimetic oligopeptide‐68 with other hypopigmenting/exfoliating agents and sunscreen provides effective and convenient treatment for facial melasma. Either is equal to or is better than 4% hydroquinone on normal skin." Journal of cosmetic dermatology 15.2 (2016): 131-144.

Products with Oligopeptide-68

Pevonia Lumafirm Cream MAKE Beauty Moonlight Brightening Serum RejuvAus Super Whitening & Brightening Pigment Serum Rx Urban Skin Rx Clear Complexion Acne Serum + Spot Treatment SVR Clairial Cream 10 NIOD Re: Pigment AlumierMD Eventone esmi skin minerals Pomegranate Brightening Serum Roccoco Botanicals Skin Brightening C Serum Wet n Wild Mega Jelly Face Primer Biologique Recherche Serum Pigm 400 Le Mieux Brightening Cleanser Skin doctors SD White & Bright Ahava Age Control Brightening And Renewal Serum SMD Cosmetics Saromae Snail Serum Concentrate Dr. brandt Dark Spots No More Serum Concentrate Innertrue Essence Of Life Freezeframe Hyper White Skin 2 Skin 24/7 Rejuvenation, Complete Anti-Aging Solution Ducray Melascreen Photoprotection Global Serum Glytone Enhance Brightening Serum Revive Skincare Perfectif Even Skin Tone Cream Spf 30 Divine Derriere 5% Alpha Arbutin Whitening Cream - Dark Spot Corrector Skinoxy Advanced Vit C Peptide Booster Serum 3LAB Super Face Serum Bionike Defence B-Lucent Skin-Evening Concentrate Bionike B-Lucent Naruko Am + Pm Peptid Spf 50 Ducray Melascreen Photo-Aging Night Cream Naruko Apple Seed & Tranexamic Acid Black Spots Defying Essence Wet n Wild Lip Treatment Wet n Wild Photo Focus Rose Primer Serum Langé Paris Bb Creme Sublime Moi Spf 10 Wet n Wild Photo Focus Hydrating Balm Stick Wet n Wild Prime Focus Primer Serum Soleil Toujours After Sun Rescue + Repair Brightening Serum Awake Beauty Hello, Sunshine Moisturizer Peter Thomas Roth Laser-Free Resurfacing Eye Serum Wardah Crystallure Supreme Revitalizing Rich Cream 35 Pa+++ Hydroxatone Anti-Aging Bb Cream AMPU Seal The Deal Moisturizing Sorbet The Plant Base White Truffle Aura Cream-Gel Zo skin health Ossential® Brightalive Non-Retinol Skin Brightener The Plant Base White Truffle Ginseng Tone Up Emulsion