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Oligopeptide-68

goodie
Also-called-like-this: ß-White
What-it-does: skin brightening

Details

A skin-brightening peptide that is claimed to have a unique mechanism of action on lightening both constitutive (our default skin color) and facultative (such as tanning) pigmentation. It works by inhibiting the MITF gene that plays an important role in controlling melanin producing skin cells called melanocytes.

In the in-vivo (made on real people) test of the manufacturer, 23 Asian volunteers used a 5% ß-White formula for 56 days twice a day and 87% reported a more uniform skin tone and 91% felt that their skin was brighter than before.

As for research, we found one study from 2016 that combined Oligopeptide-68 with sunscreen and another skin-lightening active called Diacetyl Boldine (DAB). The conclusion was that "combination of DAB serum at night and DAB/TGF-β1 biomimetic oligopeptide-68/sunscreen cream in the morning and at noon was effective and safe for facial melasma. They were superior to HQ in pigment reduction."  HQ refers to the famous Hydroquinone that's the gold-standard skin-lightening ingredient, so having comparable or superior results is a very promising outcome. 

Overall, if you are into skin-lightening or fading pigmentation spots, Oligopeptide-68 might be something to try.

Show me some proof

  • Pratchyapurit, Walai‐orn. "Combined use of two formulations containing diacetyl boldine, TGF‐β1 biomimetic oligopeptide‐68 with other hypopigmenting/exfoliating agents and sunscreen provides effective and convenient treatment for facial melasma. Either is equal to or is better than 4% hydroquinone on normal skin." Journal of cosmetic dermatology 15.2 (2016): 131-144.

Products with Oligopeptide-68

KLM Tyrolite Cream Kitoderm Glowing White Serum Libra Cosmetica Therapy Be White O Cosmedics B3 Plus Elyn’s Lab Pigment C-Control Pevonia Lumafirm Cream ALHA ALFA Power Bright Dark Spot Serum Traxenamic Acid 2% FarmHouse Fresh Illumination Juice MAKE Beauty Moonlight Brightening Serum RejuvAus Super Whitening & Brightening Pigment Serum Rx Urban Skin Rx Clear Complexion Acne Serum + Spot Treatment Lissy Skincare Vitamin C Serum With Peptides Lululun One Night, Vitamins Facial Sheet Mask esmi skin minerals Pomegranate Brightening Serum FarmHouse Fresh Eternal Light SVR Clairial Cream 10 Tiny Buds Baby Naturals Brighten Up Baby Face Cream NIOD Re: Pigment AlumierMD Eventone Bielenda Professional Lift & Glow Illuminating Face Elixir COSRX The 6 Peptide Skin Booster Serum Foxtale Hyperpigmentation Serum With Tranexamic Acid Skin doctors White And Bright Skin Whitening Cream Soraya Beauty Rx Brightening Corrective Serum esmi skin minerals Pomegranate Brightening Serum Biluma Advance Cream Lululun Facial Sheet Mask, White (Brightening) NATURE’S PALLETE Vitamin C Brightening Booster Serum Roccoco Botanicals Skin Brightening C Serum Wet n Wild Mega Jelly Face Primer Bielenda Professional Lift & Glow Tightening Eye Cream Biologique Recherche Serum Pigm 400 Devine Derriere Radical Dark Spot Remover Cream Divine Derriere Intimate Area Lightening Gel Multi Actives 10% Brightening Concentrate Le Mieux Brightening Cleanser SVR Clairial Peel Skin doctors SD White & Bright Urban Skin Rx Pro Strength Hydrabalance Brightening Moisture Infusion Ahava Age Control Brightening And Renewal Serum Circadia White Veil Brightener NATCHA Beauté White Serum OMG Oh My Glow Bright Booster Face Wash SMD Cosmetics Saromae Snail Serum Concentrate Dermika Luxury Neocollagen Regenerating Toner Ethiglo Intense Skin Lightening And Brightening Ethinext Pharma Ethiglo Serum Golden Shine Whitening Water Drop Dermatouch Bye Bye Pigmentation Cream Dr. Brandt Dark Spots No More Serum Concentrate Foresta Pore And Whitening Serum