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Perricone MD Hand Therapy

Hand Therapy

Everything you’ve come to love about the Cold Plasma Plus+ treatment is now available for your hands. Strengthen, soften and replenish the look of thin, crepey skin through intense moisturization and diminish the look of dark spots, veins and discoloration.
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Perricone MD Hand Therapy
Ingredients explained

Also-called: Aqua;Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

What-it-does: moisturizer/humectant

A derivative of Urea, that works as a strong moisturizer and humectant meaning that it helps the skin to cling onto water and thus to make it hydrated and elastic.

According to manufacturer's data,  Hydroxyethyl Urea has a similar moisturizing ability to glycerin (measured at 5%), but it feels nicer on the skin as it is non-sticky and non-tacky and gives a lubricous and moist feeling to the skin.

Also-called: Shea Butter | What-it-does: emollient, viscosity controlling

Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.

But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat. 

What-it-does: emollient, solvent

A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel

A handy helper ingredient that comes in a white powder form and works as an anti-caking and oil-absorbing agent. It also gives products good spreadability, long lasting and velvet touch characteristics. It is popular both in skincare and makeup products.

What-it-does: moisturizer/humectant, solvent, viscosity controlling | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

What-it-does: emollient, perfuming | Irritancy: 0 | Comedogenicity: 2-4

A super common, medium-spreading emollient ester that gives richness to the formula and a mild feel during rubout. It can be a replacement for mineral oil and is often combined with other emollients to achieve different sensorial properties.

What-it-does: emollient, viscosity controlling | Irritancy: 0 | Comedogenicity: 2-3

A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).

What-it-does: emollient, viscosity controlling, emulsifying, emulsion stabilising, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

What-it-does: emollient, emulsifying | Irritancy: 0 | Comedogenicity: 1-2

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

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It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".

Also-called: Radianskin | What-it-does: skin brightening

skin-brightening, spot fading active ingredient that goes by the trade name Radianskin. The in-vitro (made in the lab) test results of the manufacturer show that it can prevent melanin formation more effectively than other well-known skin-lightening agents, like ascorbyl glucoside, kojic acid, or arbutin and it has equivalent efficacy to skin-lightening gold-standard ingredient hydroquinone but without cytotoxicity.

There is also a L'Oreal sponsored research showing that the combination of hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid produced comparable skin-lightening results as the standard prescription combination of 4% hydroquinone cream and 0.025% tretinoin cream after 12 weeks. 

What-it-does: surfactant/cleansing

We don't have description for this ingredient yet.

What-it-does: surfactant/cleansing, emulsifying | Irritancy: 0 | Comedogenicity: 0

A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together. 

It's often paired with glyceryl stearate - the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.

Also-called: Sunflower Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more  we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.

It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.

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Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.

It's also loaded with fatty acids (mostly linoleic (50-74%)  and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil

Truth be told, there are many great plant oils and sunflower oil is definitely one of them.

Phospholipids - goodie

A type of lipid that's the major (about 75%) component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient.

It has a water-loving head with two water-hating tails and this structure gives the molecule emulsifying properties. It is also often used to create liposomes, small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and help its absorption.

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: chelating

We don't have description for this ingredient yet.

Also-called: lye | What-it-does: buffering

The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right. 

For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.  

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BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.

Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.

What-it-does: viscosity controlling

A big molecule from repeated subunits that is used to form gel-like textures and create a film on the skin. 

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

Also-called: Alphaflow | What-it-does: emollient, perfuming, solvent

A hydrocarbon-based emollient that can come in different viscosities from silky-light through satiny-smooth to luxurious, rich. It forms a non-occlusive film on the surface of the skin and brings gloss without greasiness to the formula. It's a very pure and hypoallergenic emollient that's also ideal for baby care products. 

What-it-does: perfuming

We don't have description for this ingredient yet.

What-it-does: emulsifying

A vegetable-based, PEG-free ingredient whose job is to help water and oil to mix nicely together (emulsifier). It is created by attaching ten water-loving glycerin molecules with the oil-loving fatty acid, stearic acid. The result is a partly water- and partly oil-loving molecule that creates stable and smooth emulsions that are also cosmetically elegant. It also has some moisturizing and softening benefits for skin and hair.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does moisturizer/humectant
A derivative of Urea, that works as a strong moisturizer and humectant meaning that it helps the skin to cling onto water and thus to make it hydrated and elastic. According to manufacturer's data,  Hydroxyethyl Urea has a similar moisturizing ability to glycerin (measured at 5%), but it feels nicer on the skin as it is non-sticky and non-tacky and gives a lubri [more]
what‑it‑does emollient | viscosity controlling
Shea butter that's considered to be a magic moisturizer and emollient. It is also soothing and rich in antioxidants. [more]
what‑it‑does emollient | solvent
A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel. 
what‑it‑does viscosity controlling
A handy helper ingredient that comes in a white powder form and works as an anti-caking and oil-absorbing agent. It also gives products good spreadability, long lasting and velvet touch characteristics.
what‑it‑does moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does emollient | perfuming
irritancy, com. 0, 2-4
A super common, medium-spreading emollient ester that gives richness to the formula and a mild feel during rubout. [more]
what‑it‑does emollient | viscosity controlling
irritancy, com. 0, 2-3
A common multi-tasker fatty acid that works as an emollient, thickener and emulsion stabilizer. [more]
what‑it‑does emollient | viscosity controlling | emulsifying | surfactant/cleansing
irritancy, com. 1, 2
A super common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams. [more]
what‑it‑does emollient
irritancy, com. 0, 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
what‑it‑does emollient | emulsifying
irritancy, com. 0, 1-2
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
what‑it‑does skin brightening
A skin-brightening, spot fading active ingredient that's claimed to have equivalent efficacy to skin-lightening gold-standard ingredient hydroquinone but without cytotoxicity. [more]
what‑it‑does surfactant/cleansing
what‑it‑does surfactant/cleansing | emulsifying
irritancy, com. 0, 0
A commonly used water-soluble surfactant and emulsifier. [more]
what‑it‑does emollient
irritancy, com. 0, 0
Sunflower Oil - it's a great emollient that protects & enhances the skin barrier. [more]
what‑it‑does skin-identical ingredient | emollient
A type of lipid that's the major component of all cell membranes. As for skincare, it works as an emollient and skin-identical ingredient. It's also often used to create liposomes. [more]
what‑it‑does viscosity controlling | emulsifying | surfactant/cleansing
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does chelating
what‑it‑does buffering
Lye - A solid white stuff that’s very alkaline and used in small amount to adjust the pH of the product.  [more]
what‑it‑does viscosity controlling
A big molecule from repeated subunits that is used to form gel-like textures and create a film on the skin.  [more]
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
what‑it‑does emollient | perfuming | solvent
A hydrocarbon-based emollient that can come in different viscosities from silky-light to luxurious, rich. It forms a non-occlusive film on the surface of the skin. [more]
what‑it‑does perfuming
what‑it‑does emulsifying
A vegetable-based, PEG-free ingredient whose job is to help water and oil to mix nicely together (emulsifier). It is created by attaching ten water-loving glycerin molecules with the oil-loving fatty acid, stearic acid. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]