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TIS farmaceutic Urea Cream 15%

Urea Cream 15%

For very dry skin.
Uploaded by: alinam26 on

TIS farmaceutic Urea Cream 15%
Ingredients explained

Also-called: Petroleum jelly, Vaseline | What-it-does: emollient

The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.

The unique thing about petrolatum is that it is the most effective occlusive agent known today. While the occlusivity of mineral oil is in the same league as the occlusivity of plant oils, petrolatum is in a league of its own. It sits on top of the skin and hinders so-called transepidermal water loss (TEWL) like nothing else.

Also-called: Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Urea - goodie
Also-called: Carbamide | What-it-does: skin-identical ingredient, moisturizer/humectant

Yes, it's the thing that can be found naturally in pee. And in the skin. It is an awesome natural moisturizing factor, aka NMF.  NMFs are important components that help the skin to hold onto water and keep it plump, elastic and hydrated. Urea makes up about 7% of NMFs next to other things such as amino acids (40%), PCA (12%) or Lactate (12%).

What makes urea special, is that it is not only a simple moisturizer, but it is thought to be a "small-molecule regulator of epidermal structure and function" meaning that it has a bunch of extra biological activities. It acts as a mild keratolytic agent (some of its moisturizing action is thought to come from urea's ability to break down bonds in the protein called filaggrin and thus freeing up amino acids in the skin), enhances antimicrobial peptide expression and improves skin barrier function

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Also-called: Wheat Germ Extract

It's a plant extract that comes from wheat germ. Used as skin- and hair conditioner and skin protectant.

Contains gluten, if you are allergic.

What-it-does: emollient, viscosity controlling, emulsion stabilising | Irritancy: 2 | Comedogenicity: 2

A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). Can be derived from coconut or palm kernel oil.

Also-called: Licorice Root;Glycyrrhiza Glabra Root Extract | What-it-does: soothing, skin brightening

You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. It's sweet and yellow and not only used for licorice all sorts but it's also a skincare superstar thanks to two magic properties:

Nr. 1 magic property is that it has skin-lightening or to say it another way depigmenting properties. The most active part is called glabridin. The topical application (meaning when you put it on your face) of 0.5% glabridin was shown to inhibit UVB caused pigmentation of guinea pigs. Another study even suggested that licorice is more effective than the gold standard skin-lightening agent hydroquinone. All in all, licorice is considered to be one of the safest skin lightening agents with the fewest side effects.

What-it-does: emollient, emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0-1

We don't have description for this ingredient yet.

What-it-does: emollient, emulsifying | Irritancy: 0 | Comedogenicity: 1-2

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

Also-called: Plantain Leaf Extract | What-it-does: soothing, antioxidant, antimicrobial/antibacterial

The plant extract coming from the leaves of English plantain or narrowleaf plantain that's native to Europe and Asia. The plant has plenty of traditional medicinal uses. Regarding the leaf and the skin, it's used to promote maturation of abscess and to speed up the recovery of incisions, pimples or wounds. 

Modern studies do confirm that the plant, and specifically the leaves are loaded with active compounds that give the extract anti-inflammatory, antibacterial, and antioxidant magic properties. An in-vitro (made on chicken membrane, not on real people) study in Phytotherapy Research found that Plantain Leaf Extract in large concentrations has a comparable soothing effect to anti-inflammatory big shot, hydrocortisone.

Also-called: Calendula Extract, Marigold Extract | What-it-does: soothing, antioxidant, perfuming

The extract coming from the popular garden plant Calendula or Marigold. According to manufacturer info, it's used  for many centuries for its exceptional healing powers and is particularly remarkable in the treatment of wounds. It contains flavonoids that give the plant anti-inflammatory and antioxidant properties. 

Also-called: Mineral Oil | What-it-does: emollient, solvent | Irritancy: 0 | Comedogenicity: 0-2

The famous or maybe rather infamous mineral oil. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. It is a very controversial ingredient with pros and cons and plenty of myths around it. So let us see them:  

The pros of mineral oil
Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert.

It is a great emollient and moisturizer working mainly by occlusivity. Occlusivity is one of the basic mechanisms of how moisturizers work and it means that mineral oil sits on top of the skin and hinders so-called trans-epidermal water loss, i.e water evaporating out of your skin. When compared to heavy-duty plant oil, extra virgin coconut oil, the two of them were equally efficient and safe as moisturizers in treating xerosis, a skin condition connected to very dry skin.

Lactic Acid - superstar
  • It’s the second most researched AHA after glycolic acid
  • It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
  • It also has amazing skin hydrating properties
  • In higher concentration (10% and up) it improves skin firmness, thickness and wrinkles
  • Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
  • Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
Read all the geeky details about Lactic Acid here >>

Also-called: Carrot Root Oil | What-it-does: antioxidant, emollient

The oil-soluble extract coming from the edible, orange part of the carrot. It is created by macerating the carrot root in a carrier oil such as sunflower or olive oil, and the resulting thing (base oil + carrot root extract) is often called carrot oil or carrot root oil. (Not to be confused with carrot seed oil, that can be fixed or essential and comes from the seeds.)

The root extract is known for containing the orange pigment beta-carotene, aka provitamin A. It is a famous molecule for being a potent antioxidant, suntan accelerator and having skin-regenerative abilities. Carrot oil also contains vitamin E and some fatty acids that give the oil further antioxidant and barrier repairing properties. 

Salicylic Acid - superstar
Also-called: BHA | What-it-does: exfoliant, anti-acne, soothing, preservative
  • It's one of the gold standard ingredients for treating problem skin
  • It can exfoliate skin both on the surface and in the pores
  • It's a potent anti-inflammatory agent
  • It's more effective for treating blackheads than acne
  • For acne combine it with antibacterial agents like benzoyl peroxide or azelaic acid
Read all the geeky details about Salicylic Acid here >>

You may also want to take a look at...

what‑it‑does emollient
The famous Vaseline or Petroleum Jelly. Just like mineral oil, it is also a by-product of refining crude oil, aka petroleum, and it is also a mixture of hydrocarbons but with bigger (C18-90+) carbon chain length.The unique thing about petrolatum is that it is the most effective occlusive agent known today. [more]
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
The thing in the pee that is also a natural moisturizing factor (NMF) with mild keratolytic and strong skin moisturizing superpowers. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
A plant extract that comes from wheat germ. Used as skin- and hair conditioner and skin protectant.
what‑it‑does emollient | viscosity controlling
irritancy, com. 2, 2
A fatty (the good, non-drying kind of) alcohol that makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier).
what‑it‑does soothing | skin brightening
You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. [more]
what‑it‑does emollient | emulsifying | surfactant/cleansing
irritancy, com. 0, 0-1
what‑it‑does emollient | emulsifying
irritancy, com. 0, 1-2
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
what‑it‑does soothing | antioxidant | antimicrobial/antibacterial
Plantain Leaf Extract that has's used traditionally to speed up abscess, and the healing of pimples and incisions. Modern studies confirm that the plant has potent anti-inflammatory and soothing properties. [more]
what‑it‑does soothing | antioxidant | perfuming
Marigold extract - contains flavonoids that give the plant anti-inflammatory and antioxidant properties. [more]
what‑it‑does emollient | solvent
irritancy, com. 0, 0-2
A clear, oily liquid that comes from refining crude oil. Even though it is a highly controversial ingredient, the scientific consensus is that it is a safe, non-irritating and effective emollient and moisturizer working mainly by occlusivity. [more]
what‑it‑does exfoliant | moisturizer/humectant | buffering
A superstar AHA that not only exfoliates skin but is also a very good moisturizer. In higher concentration (10% and up) it can even improve skin firmness, thickness, and wrinkles. [more]
what‑it‑does antioxidant | emollient
The oil-soluble extract coming from the edible, orange part of the carrot. It is created by macerating the carrot root in a carrier oil such as sunflower or olive oil, and the resulting thing (base oil + carrot root extract) is often called carrot oil or carrot root oil. [more]
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores and it's a potent anti-inflammatory agent. [more]